Cor et Vasa - Latest articles

The clinical and angiographic impact of intravascular ultrasound guided stenting of unprotected left main and proximal left anterior descending coronary artery. A prospective randomized controlled study in EgyptOriginal research articles

Noha Hassanin Hanboly, Yasser Mohamed Kamel Baghdady, Mostafa Mokhtar Mostafa, Assem Abdelaziz Fahmy Hashad, Yasser Ahmed Sadek

Cor Vasa 2023, 65(3):468-476 | DOI: 10.33678/cor.2022.101  

Background: Coronary angiography has some limitations in the proper assessment of coronary artery le- sions. Intravascular ultrasound (IVUS) before percutaneous coronary intervention (PCI) can identify significant stenosis, select the appropriate stent and detect complications. The study aimed to evaluate the impact of intravascular ultrasound on clinical and angiographic outcomes after revascularization by stenting for patients with unprotected left main (ULM) or proximal left anterior descending (LAD) coronary artery disease (CAD). Materials and methods: A prospective randomized controlled study that was carried on sixty patients presented with stable...

The impact of the cardiovascular risk factors on short-term in-hospital outcome of patients with COVID-19Original research articles

Noha Hassanin Hanboly, Sameh Wadie, Reda Hussain Diab, Mohamed Omar

Cor Vasa 2023, 65(3):461-467 | DOI: 10.33678/cor.2022.095  

Background: Coronavirus disease (COVID-19) has caused significant morbidity and mortality. COVID-19 is more than a respiratory illness, it had multiple systemic effects such as myocarditis, arrhythmias, and venous thromboembolism. Aim of the study: We aimed to study the frequency of cardiovascular risk factors in patients with COVID-19 and the impact of these risk factors on short-term in-hospital outcome of patients newly discovered with COVID-19. Materials and methods: Cross-sectional analytic study conducted in Egypt on 200 patients (mean age of 44.2±12.7 years old) with positive polymerase chain reaction for COVID-19 recruited from different...

(Endovascular treatment of abdominal aortic aneurysm with angulated neck)Original research articles

Khaled El Samman, Petr Šedivý, Helena Přindišová, Alena Šnajdrová

Cor Vasa 2023, 65(3):455-459 | DOI: 10.33678/cor.2023.017  

Aim: To evaluate the technical and clinical success of stent graft implantation in abdominal aortic aneurysm (AAA) with neck angulated more than 60 degrees. Methods: We retrospectively analyzed the outcomes of endovascular treatment of subrenal aortic aneurysm (EVAR) performed from 2013 to 2021 in patients with AAA neck angulation greater than 60 degrees. The cohort consists of 27 patients with neck angulation of 65-95 degrees. Results: In all 27 cases the stent graft (SG) was correctly implanted by the same endovascular team. Type I endoleak was present in 2 patients. In the first case, we managed the endoleak with proximal SG exten- sion, in the...

(Implantation of leadless pacemaker (LP) Micra - single center experience)Original research articles

Jan Boček, Markéta Segeťová, Jan Beneš, Hanka Wünschová, Kamil Sedláček, Věra Lánská, Josef Kautzner

Cor Vasa 2023, 65(3):447-453 | DOI: 10.33678/cor.2022.104  

Introduction: Since beginning of cardiac pacing, implanters have been facing problems related to the weakest part of pacing system - pacing leads. Historically, there were problems with lead insulation or coating; another problem is lead or fixating helix fracture.^1,2 Infection of cardiac implantable electronic devices (CIEDs) is also a significant issue.^3,4 As a reaction to these challenges, the concept of leadless pacing was developed. In this stimulation modality, miniature pacemaker is implanted directly into cavity of right

Jiří Šedý: Kritické myšleníBook reviews

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2023, 65(2):440  

Hana Skalická, Miloš Táborský a kolektiv: Ambulantní kardiologie v praxi Snadno a s přehledemBook reviews

Prof. MUDr. Michael Aschermann, DrSc.,

Cor Vasa 2023, 65(2):439  

(2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).Guidelines

Radek Pudil, Vilém Danzig, Jiří Veselý, Filip Málek, Miloš Táborský, Lubomír Elbl, Aleš Linhart, Hana Skalická

Cor Vasa 2023, 65(2):350-434 | DOI: 10.33678/cor.2023.032  

Translation of the shortened document prepared by the Czech Society of Cardiology)Lyon AR, López-Fernández T, Couch LS, Asteggiano R, Aznar MC, Bergler-Klein J, Boriani G, Cardinale D, Cordoba R, Cosyns B, Cutter DJ, de Azambuja E, de Boer RA, Dent SF, Farmakis D, Gevaert SA, Gorog DA, Herrmann J, Lenihan D, Moslehi J, Moura B, Salinger SS, Stephens R, Suter TM, Szmit S, Tamargo J, Thavendiranathan P, Tocchetti CG, van der Meer P, van der Pal HJH; ESC Scientific Document Group.

(2022 ESC Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery.)Guidelines

Hana Skalická, Miloš Táborský

Cor Vasa 2023, 65(2):287-349 | DOI: 10.33678/cor.2023.034  

Translation of the shortened document prepared by the Czech Society of Cardiology)Halvorsen S, Mehilli J, Cassese S, Hall TS, Abdelhamid M, Barbato E, De Hert S, de Laval I, Geisler T, Hinterbuchner L, Ibanez B, Lenarczyk R, Mansmann UR, McGreavy P, Mueller C, Muneretto C, Niessner A, Potpara TS, Ristić A, Sade LE, Schirmer H, Schüpke S, Sillesen H, Skulstad H, Torracca L, Tutarel O, Van Der Meer P, Wojakowski W, Zacharowski K; ESC Scientific Document Group.

(2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Endorsed by the International Society for Heart and Lung Transplantation (ISHLT) and the European Reference Network on rare respiratory diseases (ERN-LUNG).Guidelines

Pavel Jansa, David Ambrož, Michael Aschermann, Marián Felšöci, Martin Hutyra, Radek Pudil, Jaroslav Lindner

Cor Vasa 2023, 65(2):236-286 | DOI: 10.33678/cor.2023.033  

Translation of the shortened document prepared by the Czech Society of Cardiology)Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M, Carlsen J, Coats AJS, Escribano-Subias P, Ferrari P, Ferreira DS, Ghofrani HA, Giannakoulas G, Kiely DG, Mayer E, Meszaros G, Nagavci B, Olsson KM, Pepke-Zaba J, Quint JK, Rådegran G, Simonneau G, Sitbon O, Tonia T, Toshner M, Vachiery JL, Vonk Noordegraaf A, Delcroix M, Rosenkranz S; ESC/ERS Scientific Document Group.

(2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death.)Guidelines

Petr Peichl, Alan Bulava, Ondřej Toman, Josef Kautzner

Cor Vasa 2023, 65(2):186-235 | DOI: 10.33678/cor.2023.023  

(Translation of the shortened document prepared by the Czech Society of Cardiology)Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA, Charron P, Corrado D, Dagres N, de Chillou C, Eckardt L, Friede T, Haugaa KH, Hocini M, Lambiase PD, Marijon E, Merino JL, Peichl P, Priori SG, Reichlin T, Schulz-Menger J, Sticherling C, Tzeis S, Verstrael A, Volterrani M; ESC Scientific Document Group.

(Multisystem inflammatory syndrome in adults in cardiology intensive care unit, brief summary and case report)Review articles

Martin Vojtíšek, Nedal Omran, Tereza Špornová, Pavel Červinka

Cor Vasa 2023, 65(2):181-185 | DOI: 10.33678/cor.2022.120  

Background: As a part of world-wide spreading COVID-19 disease pandemic, a life-threatening syndrome affecting predominantly young adults was discovered. This entity usually occurs within 4 weeks after the onset of SARS-CoV-2 infection. The disease is often associated with several organ involvements, including the heart. This newly emerging unit is known as multisystem inflammatory syndrome in adults (MIS-A). Case presentation: We describe a case of a 29-year-old patient with MIS-A with predominant cardiac involvement. At admission the patient experienced fever and signs of acute left-sided heart failure, which was thought to be associated with recent...

Vyhlášení soutěže o nejlepší publikaci v roce 2023Informations

Michael Aschermann

Cor Vasa 2023, 65(1):6  

Czech Cardiovascular Research and Innovation Day 2022 - AbstractsAbstracts

Cor Vasa 2023, 65(1):141-172  

František Koukolík: DrbyBook reviews

Jan Petrášek

Cor Vasa 2023, 65(1):140  

Čestmír Číhalík: Kardiologie v průběhu stoletíBook reviews

Jan Petrášek

Cor Vasa 2023, 65(1):139  

Pan profesor MUDr. Jan Marek, Ph.D., FESC, slaví životní výročíPersonalia

Michael Aschermann

Cor Vasa 2023, 65(1):138  

Anomalous origin of the left circumflex artery from right sinus of Valsalva: a rare case but with great clinical relevanceCase reports

Cristina Poleggi, Davide Restelli, Alfredo Luongo, Federica Cocuzza, Francesca Campanella, Mennili Sara, Alessio Currò, Antonino Recupero, Michele Scarano

Cor Vasa 2023, 65(1):133-136 | DOI: 10.33678/cor.2022.063  

Anomalous origin of coronary artery (CA) is rare and does not generally lead to myocardial infarction. We report a case of a 61-year-old man presented with paroxysmal supraventricular tachycardia and atypical chest pain. After arrhythmia subsided, ECG showed T wave abnormalities and transient cardiac enzymes were found to be elevated. Coronary angiography demostrated an anomalous origin of the left circumflex artery (LCx) from the right sinus of Valsalva but no obstructive atherosclerotic coronary lesions. The possible relation between the congenital coronary anomaly and the clinical manifestations of the patient is discussed.

Beware of the Unexpected: Acute Coronary Thrombosis Following the Mildly Symptomatic COVID-19 Infection and Two Different Therapeutic OptionsCase reports

Murat Gul, Sinan Inci

Cor Vasa 2023, 65(1):129-132 | DOI: 10.33678/cor.2022.074  

COVID-19 infection was declared a pandemic in March 2020 and is responsible for high morbidity and mortality around the globe. Although the most common clinical presentation is respiratory, cardiac complications are common and create new challenges for healthcare. We discuss two mildly symptomatic outpatients with COVID-19 presenting with acute ST-elevation myocardial infarction (STEMI) and high coronary thrombus burden without atherosclerotic plaque. Our report describes two different therapeutic approaches that illustrate the challenges encountered in the management of disseminated coronary thrombosis in patients with STEMI and COVID-19. Clinicians...

(Cardiac tamponade as severe manifestation of angiosarcoma)Case reports

Daniel Baran, Tomáš Roubíček, Rostislav Polášek

Cor Vasa 2023, 65(1):125-128 | DOI: 10.33678/cor.2022.082  

Angiosarcoma of the heart is the most common primary malignant tumour of the heart. It is characterized by rapid and aggressive growth. It most commonly affects the right side of the heart. Cardiac imaging and histology are the most important tests leading to right diagnosis. The prognosis of angiosarcomas is very poor. The only potential curative intervention is a radical surgical resection. We describe a case of a 20-year-old man presenting with cardiac tamponade as a severe manifestation of angiosarcoma.

Post-myocardial infarction left ventricular intramyocardial dissecting hematomaCase reports

Adam Vejmělek, Petr Němec, Petr Fila

Cor Vasa 2023, 65(1):120-124 | DOI: 10.33678/cor.2022.089  

Background: Intramyocardial dissecting hematoma (IDH) is blood-filled cavitation in the cardiac wall that can occur as a complication of myocardial infarction, chest trauma, or percutaneous intervention. It can develop in the left ventricular free wall, the right ventricle, or the interventricular septum. Case report: The case report describes a patient with IDH as a rare complication of myocardial infarction. The patient was hospitalized for ongoing irritating cough three months after ST elevated myocardial infarction treated with percutaneous coronary intervention. The echocardiography showed the image of a pseudoaneu- rysm of the left ventricle....

Post‑infectious acute myocardial infarction following COVID‑19 infection in a young patientCase reports

Rodolfo Caminiti, Giampaolo Vetta, Antonio Parlavecchio, Michele Magnocavallo, Stefano Postorino, Scipione Carerj, Francesco Antonio Benedetto

Cor Vasa 2023, 65(1):116-119 | DOI: 10.33678/cor.2022.064  

It is now widely known that COVID-19 can also cause various extrapulmonary manifestations. Possible mechanisms of cardiovascular damage include direct myocardial damage due to hypercoagulability caused by systemic inflammation, which may also lead to destabilisation of coronary plaques. We present a case of a 30-year-old young man following asymptomatic COVID-19 infection, who was admit- ted to the emergency room of the Grande Ospedale Metropolitano di Reggio Calabria, Italy, with typical chest pain. The patient had no cardiovascular disease, cardiovascular risk factors including no family history of cardiovascular disease. Urgent coronary angiography...

Surgical management of ascending aorta pseudoaneurysm in a patient with COVID-19Case reports

Sandra Rečičárová, Peter Ivák, Jan Pirk

Cor Vasa 2023, 65(1):113-115 | DOI: 10.33678/cor.2022.060  

Pseudoaneurysm of the thoracic aorta is a rare condition associated with high mortality. We present a case of a patient who developed a huge pseudoaneurysm 10 years after the Bentall procedure and one aortocoronary bypass while simultaneously being COVID-19 positive. After treating pneumonia, the surgery was successfully performed with suturing two defects in the aortic conduit. It is a unique case report where the patient survived two life-threatening conditions.

(Catheterizational Closure of a Persistent Botallo's Duct in a Patient After Endovascular Treatment of Aortic Dissection Type B)Case reports

Jan Švejda, Ladislav Pešl, Jiří Haniš, Aleš Mokráček

Cor Vasa 2023, 65(1):107-112 | DOI: 10.33678/cor.2022.051  

In patients diagnosed with an acute aortic dissection type B according to the Stanford classification, thoracic endovascular repair (TEVAR) is the primary recommended treatment in cases with a complicated course. The purpose of implanting a stent graft is to close the entry point of the dissection, thus hopefully causing a thrombus to fill the false lumen throughout the whole stent graft, stabilizing the thoracic aortic wall. In our case report, the thrombus unfortunately did not form, the reason being continuous flow through the false lumen due to an undiagnosed persisting Botallo's duct. The solution to this complication was closing the persisting...

(Pseudoaneurysm of radial artery as a complication of selective coronary catheterization)Case reports

Josef Laštůvka, Martin Porzer, Marian Branny, Leoš Pleva, Jan Mrózek, Pavel Kukla, Tomáš Grézl

Cor Vasa 2023, 65(1):104-106 | DOI: 10.33678/cor.2022.042  

Selective coronary angiography is a routine examination with a low risk of serious complications.¹ In recent years, with regards to minimizing the risk of local complications and comfort of the patient, the transradial access has been used as the dominant approach. Among the local complications of this approach the most frequent are spasm, radial artery occlusion (ORA), and non-occlusive damage. In rare cases, it is a vessel perforation, pseudoaneurysm, AV fistula, nerve damage, thromboembolization or major bleeding.^2,3 In our case study, we want to show an example where, after several years, a pseudoaneurysm of the radial artery...

Is the Atherogenic Index of Plasma (AIP) a Cardiovascular Disease Marker?Review articles

Lutfu Askin, Okan Tanriverdi

Cor Vasa 2023, 65(1):100-103 | DOI: 10.33678/cor.2022.085  

Numerous indicators have been used to diagnose and prognosticate cardiovascular disease (CVD). The atherogenic index of plasma (AIP) is a logarithmic conversion of triglyceride (TG) to high-density lipoprotein (HDL) molar concentrations. The close association between AIP and the size of lipoprotein particles may account for its excellent predictive value. AIP may be computed simply using a typical lipid profile. It is a bet- ter predictor of lipoprotein particle size than that of individual lipids or the ratio of TG to HDL.

Prosthetic valve thrombosis: literature review and two case reportsReview articles

Kotryna Druteikaitė, Simona Bėrontaitė, Gintarė Valterytė, Gediminas Jaruševičius

Cor Vasa 2023, 65(1):90-99 | DOI: 10.33678/cor.2022.054  

Prosthetic heart valve thrombosis is one of the most dangerous prosthetic valve complications. Proper monitoring and management of these patients help to prevent this complication. Fluoroscopy is advantageous in cases of thrombosis to assess the function of the prosthetic valve by measuring opening and closing angles. We describe two cases of aortic mechanical valve thrombosis with different mechanisms of thrombus formation. The first case was a 48-year-old woman admitted to the hospital because of shortness of breath during minimal exertion and significantly reduced exercise tolerance. Due to rheumatic heart disease the patient underwent aortic and...

Myocarditis in childrenReview articles

Kristina Rücklová, Jan David, Karel Koubský, Jan Pavlíček, Eva Klásková, Vojtěch Šedivý, Sylvia Krupičková, Hana Malcová, Jitka Komínová, Pavel Vít, Peter Kubuš

Cor Vasa 2023, 65(1):82-89 | DOI: 10.33678/cor.2022.096  

Myocarditis in children is a relatively rare disease which often presents a dilemma that has to be faced not only by paediatric cardiologists but also paediatricians. The diagnosis often remains clinically suspected or probable. Only recent advancements in cardiac magnetic resonance have enabled us to confirm the diagno- sis. However, it may not be readily available. Scientific statement of the American Heart Association on paediatric myocarditis was published in 2021 and provides useful support for treatment. Hence, this article is a result of published guidelines.

(Why to use fixed dose perindopril, bisoprolol combination in hypertonics with CHD?)Review articles

Ondřej Petrák

Cor Vasa 2023, 65(1):77-81 | DOI: 10.33678/cor.2023.004  

Cardiovascular disease is the leading cause of mortality worldwide. Arterial hypertension is one of the earliest risk factors of atherosclerosis and early intervention significantly reduces cardiovascular morbidity and mortality. We have to tailor the treatment to individual patients according to their hypertension subclass and their cardiovascular and metabolic risk profile. The fixed combination has a number of advantages, from better and faster achievement of blood pressure target values, through fewer side effects to improved adherence to treatment. The combination of a beta-blocker (bisoprolol) and an ACE inhibitor (perindopril) has complementary...

Inclisiran: new era of lipid-lowering therapy?Review articles

Jan Beneš

Cor Vasa 2023, 65(1):69-75 | DOI: 10.33678/cor.2022.043  

Dyslipidemia is the most frequent metabolic abnormality in western world population and a major risk factor for coronary artery disease (CAD) development. Dyslipidemia treatment is still insufficient and achieving target LDL-level infrequent. Statins are a cornerstone of dyslipidemia management. Although statins are one of the safest drugs on the market, statin therapy can be associated with muscle symptoms and increased risk of DM development. Statin discontinuation is frequent, often driven by negative media coverage. Inclisiran is a therapeutic oligonucleotide that employs RNA interference and inhibits the translation of PCSK9-mRNA leading to long-lasting...

Is the microRNA-221/222 Cluster Ushering in a New Age of Cardiovascular Diseases?Review articles

Lutfu Askin, Okan Tanriverdi

Cor Vasa 2023, 65(1):65-67 | DOI: 10.33678/cor.2022.050  

In addition to regulating gene expression, microRNAs (MiRs) regulate messenger RNA degradation and translation rates. MiRs have a high expression in the cardiovascular (CV) system, indicating an important role in vascular health. The atherosclerotic process has been related to miRs-221 and -222. MiRs-221/222 possess anti-stenotic activity. MiR-221/222 may potentially serve as a marker for myocardial remodeling. There is still a long way yet before miRs-221/222 can be recognized as a potential therapeutic target. Identification, validation, and understanding of the function of gene targets are all critical.