Editorial

Miloš Táborský

Cor Vasa 2011, 53(6-7):315  

Continuous positive airway pressure ventilation therapy in obstructive sleep apnea syndrome in context with heart frequency autonomic regulation

Jan Galuszka, Milada Hobzová, Kateřina Langová, Miloš Táborský, Ivana Buriánková, Soňa Panáková

Cor Vasa 2011, 53(6-7):314-317 | DOI: 10.33678/cor.2011.078  

Aim: Prospective evaluation of heart rate variability parameters in patients with obstructive sleep apnea syndrome treated with continuous positive airway pressure.Patients and methods: Patients with OSAS treated in the Department of Respiratory Diseases University Hospital Olomouc in the 2007-2008 period. CPAP treated group of 100 patients was compared to non-CPAP group of 20 patients. The following parameters of heart rate variability during supine-standing-supine test were evaluated: LF/HF ratio, MSSD (ms2). Two evaluations were performed: the first one at the time of OSAS diagnosis and the second one on CPAP therapy several months later.Results:...

Radiation exposure of operator during coronary angiography and coronary intervention: comparison of left radial and femoral accesses

Roman Štípal, Jiří Ostřanský, David Richter, Martin Sluka, Marcela Škvařilová, Martin Zaoral, Miloš Táborský

Cor Vasa 2011, 53(6-7):318-321 | DOI: 10.33678/cor.2011.080  

Aim: To compare the radiation dose equivalent during selective coronary angiography (SCA) and SCA followed by percutaneous coronary intervention (PCI) by left radial (LRA) and femoral (FA) accesses.Methods: 380 consecutive patients, 66.6 ± 10.5 years old, 68.9% of men, BMI 29.4 ± 5.0, were examined. By LRA 70.2% (50% SCA and 20.2% PCI), by FA 29.8% (14% SCA and 15.8% PCI) procedures were performed. During each procedure, LRA vs. FA comparisons of radiation time and radiation dose were registered.Results: There was no diference in selective coronary angiography group between LRA vs. FA concerning gender, age, BMI and radiation...

Our experience with percutaneous aortic valve implantation (TAVI)

Jiří Ostřanský, Martin Sluka, Marek Richter, Martin Hutyra, Kateřina Maderová, Vladimír Lonský, Roman Štípal, David Richter, Miloš Táborský

Cor Vasa 2011, 53(6-7):322-327 | DOI: 10.33678/cor.2011.081  

Introduction: Although surgical aortic valve replacement is a gold standard for the treatment of severe aortic valve stenosis, transcatheter aortic valve implantation (TAVI) is an established method in high surgical risk patients with clearly proved effectiveness and safety. Our first experience with this method is described.Methods: During 2010, the aortic valve implantation using CoreValve Revalving 18F system was performed in 6 patients; the selection of the patients and the course of the procedure are described. Among 39 examined patients the mean age was 82 years, mean value of logistic EuroSCORE 29.9%, indexed aortic valve area 0.33 cm2/m2...

The effect of a biocompatible coated cardiopulmonary bypass system on fibrinogen levels as determined by the TEG Functional Fibrinogen method - preliminary results

Ivo Fluger, Kateřina Maderová, Martin Šimek, Roman Hájek, Vladimír Lonský, Jana Zapletalová

Cor Vasa 2011, 53(6-7):328-332 | DOI: 10.33678/cor.2011.082  

When cardiopulmonary bypass (CPB) is used, the blood comes into contact with foreign surfaces. It causes an activation of numerous cascade and cell systems, including coagulation. To diminish this impact, various types of biocompatible coated surfaces have been developed. We studied the effect of heparin-coated CPB systems on the level and function of fibrinogen as measured by TEG, compared with non-coated systems. No statistically significant differences between both groups were revealed by comparing paired data.

Endoscopic vein harvesting for coronary artery bypass grafting. Five-year single centre experience

Martin Šimek, Marek Gwozdziewicz, Pavel Marcián, Kateřina Langová, Petr Šantavý, Andrea Steriovský, Ivo Fluger, Vladimír Lonský

Cor Vasa 2011, 53(6-7):333-339 | DOI: 10.33678/cor.2011.083  

Aim: To determine the outcome of endoscopic vein harvesting for CABG and impact of growing experience with method on its performance.Methods: From September 2005 to September 2010, endoscopic vein harvesting was carried out in the group of 400 elective patients.Demographic, perioperative, and outcome data was followed-up prospectively to assess impact of growing experience on the results of the method. Furthermore, univariable analysis focused on impact of wound-healing complication risk factors was added.Results: Mean age was 68.9 ± 8.5 years, men dominated over women (69 vs. 31%), and mean BMI reached 31.1 ± 4.1. The mean...

Surgical options of the left-ventricular lead implantation methods for cardiac resynchronization therapy

Petr Šantavý, Marián Fedorco, Vladimír Lonský

Cor Vasa 2011, 53(6-7):340-342 | DOI: 10.33678/cor.2011.084  

Cardiac resynchronization therapy is an option in patients with advanced congestive heart failure. Left ventricle lead implantation into place with latest mechanical activation is important for clinical success. Surgical implantation is a good choice in case of coronary sinus lead insertion failure. We demonstrate review of mini-invasive surgical left-ventricular lead implantation methods. We also present our group of 34 patients who underwent implantation through mini-thoracotomy access.

Use of spironolactone in the treatment of resistant arterial hypertension

Jan Václavík, Eva Kociánová, Miloš Táborský

Cor Vasa 2011, 53(6-7):343-347 | DOI: 10.33678/cor.2011.085  

Spironolactone is a mineralocorticoid receptor antagonist which lowers blood pressure. This review article summarizes the results of published trials of spironolactone in patients with resistant arterial hypertension. A number of small, uncontrolled trials showed a pronounced antihypertensive effect of small doses of spironolactone. In the randomized trials, including the recently published ASPIRANT trial, the magnitude of blood pressure fall in the spironolactone group compared to the placebo group was smaller and only systolic blood pressure was lowered significantly. We also discuss the laboratory predictors of blood pressure response to spironolactone...

Acute pulmonary embolism and patent foramen ovale - neglected risk association

Martin Hutyra, David Vindiš, Daniel Šaňák, Tomáš Skála

Cor Vasa 2011, 53(6-7):348-352 | DOI: 10.33678/cor.2011.086  

Patent foramen ovale (PFO) is a physiological variety characterized by the presence of a minimal shunt flow through the interatrial septum, with the incidence of 17-27% in a non-selected population. Acute pulmonary embolism is a relatively frequent heterogenic clinical entity with a variable clinical manifestation. Paradoxical embolization through PFO from the venous system is considered the basic pathogenetic mechanism. PFO morphology is one of the major risk determinants of this ischemic complication. Another possibility of embolization to brain circulation occurrence is in-situ thrombosis directly in the canal of PFO due to haemostasis or hypercoagulation.Bidirectional...

The J wave syndrome (the Osborn wave)

Petr Heinc, Tomáš Skála, Miloš Táborský

Cor Vasa 2011, 53(6-7):353-359 | DOI: 10.33678/cor.2011.087  

J wave syndrome is a complex of clinical features characterized by early repolarization, ST segment elevation and J wave - mediated by transient accentuation of the potassium outward current Ito. The risks of sudden cardiac death of these syndromes differ with respect to the magnitude and location of abnormal J wave manifestation and ST segment elevation. The congenital forms of J wave syndromes include early repolarization, which can be divided into three subtypes according to J wave location and the risk of arrhythmogenesis, and the Brugada syndrome. Acquired forms of J wave syndrome can occur due to some pathological conditions like hypothermia...

Lack of effect of cardiac resynchronization therapy in some patients - still unresolved problem

Miloš Táborský, Vlastimil Doupal

Cor Vasa 2011, 53(6-7):360-364 | DOI: 10.33678/cor.2011.088  

A variable percentage of patients with advanced heart failure and ventricular dyssynchrony treated with cardiac resynchronization therapy (CRT) do not benefit from this treatment (the so called non-responders). Efforts to select more eligible patients to maximize the use of human and financial resources have not been very successful. It may be better to define non-responders using a combination of several criteria, such as certain echocardiographic parameters, etiology of the underlying disease, detection of the size and location of the scar by magnetic resonance imaging and late enhancement, and many others, than setting a "universal" cut-off value....

Chemokine MCP-1 and atherosclerosis

Jana Petřková

Cor Vasa 2011, 53(6-7):365-368 | DOI: 10.33678/cor.2011.089  

Atherosclerosis has been defined as systemic, chronic inflammatory disease characterized by degenerative processes and extracellular accumulation of lipids.Inflammation is important pathogenetic mechanism of atherosclerosis whose clinical manifestations comprise diseases of distinct location. Chemotactic cytokines and their receptors play key role in atherogenesis. Expression and function of these molecules is influenced by variability (polymorphisms) in their encoding genes.Translational research in pathobiology of cardiovascular disorders aims at extending the current spectrum of laboratory parameters with new markers, which could help us...

The role of real-time 3D echocardiography in atrial structure assessment

Dan Marek

Cor Vasa 2011, 53(6-7):369-374 | DOI: 10.33678/cor.2011.090  

Three-dimensional echocardiography was developed from the post-war one-dimensional ultrasound imaging to the current routinely used method just during the last several years. Real-time 3D echocardiography has become standard high-end machine equipment. There is a vast amount of publications on its asset emerging in the literature. This article describes the role of 3D echocardiography in atrial pathology assessment - the detection of left atrial appendage thrombi or other intraatrial masses or description of septal defects, and the role of 3D echo in guiding intracardiac interventions. State-of-the-art summary and comments on own results and experience...

Right ventricular septal pacing

Tomáš Minařík, Miloš Táborský

Cor Vasa 2011, 53(6-7):375-380 | DOI: 10.33678/cor.2011.091  

Long-term right ventricular apical pacing produces asynchronous ventricular activation and contraction and is associated with left ventricular dysfunction. Right ventricular septal pacing compared to right ventricular apical pacing allows more physiological ventricular activation. The paper is an overview of studies comparing alternative right ventricular pacing sites and summarizes the anatomy of right ventricular septum and the techniques of right ventricular septal lead positioning.

Psychosocial factors as potential risk factors for sudden cardiac death

Eliška Sovová, Kateřina Ivanová, Jana Ondrušková, Dalibor Pastucha

Cor Vasa 2011, 53(6-7):381-384 | DOI: 10.33678/cor.2011.092  

Cardiovascular diseases continue to be the leading cause of death in the Czech Republic. Sudden cardiac death is defined as death from natural causes occurring within one hour of the onset of symptoms. Efforts to reduce rates of sudden cardiac death require the identification of patients with risk factors for sudden cardiac death. These can be divided into pathophysiological and psychosocial factors (i.e., lifestyle ones). Psychosocial and socioeconomic factors play a major role in the incidence of sudden cardiac death and survival rates. The factors can be subdivided into depressive disorders, anxiety disorders, anger and hostility, personality characteristics,...

Paradoxical embolism into coronary arteries - unusual cause of acute myocardial infarction

Martin Sluka, Jiří Ostřanský, David Richter, Miloš Táborský

Cor Vasa 2011, 53(6-7):385-388 | DOI: 10.33678/cor.2011.093  

Paradoxical embolism is very unusual cause of acute myocardial infarction. It is usually found in young patients and its incidence is unknown. Only less than 15 reports on this issue were published. Authors describe three cases from own professional experience during last five years.

Complete cardiosurgical implantation of biventricular defibrillator - an interdisciplinary cooperation of a cardiosurgeon and an arrhythmologist

Martin Kaláb, Marián Fedorco, Vilém Bruk, Miloš Táborský, Vladimír Lonský

Cor Vasa 2011, 53(6-7):389-392 | DOI: 10.33678/cor.2011.094  

We report the case of a patient indicated for cardiac resynchronization therapy. Previous implantations and postoperative complications made an intravasal access contraindicated. Thus, complete epicardiac implantation of electrodes was performed surgically through sternotomy, and a biventricular defibrillator was placed in the abdominal wall. AO osteosynthesis of sternum was then applied in the treatment of mechanical sternal dehiscence.

"Mozaika kardiovaskulárních onemocnění aneb Co nám ve farmakoterapii chybělo." Symposium firmy ABBOTT na výročním sjezdu České kardiologické společnosti

Jindřich Špinar

Cor Vasa 2011, 53(6-7):397-400 | DOI: 10.33678/cor.2011.098  

Srdeční frekvence a prognóza nemocných s chronickým srdečním selháním

Cor Vasa 2011, 53(6-7):401-403 | DOI: 10.33678/cor.2011.099  

Zápis ze schůze výboru ČKS konané dne 5. 4. 2011 v Brně

I. Pavézková, Michael Aschermann

Cor Vasa 2011, 53(6-7):407  

Zápis ze schůze výboru ČKS konané dne 4. 5. 2011 v Brně

P. Widimský, I. Pavézková

Cor Vasa 2011, 53(6-7):408  

Má každý pacient nárok být operován od chirurga, který to nejlépe umí?

Prof. MUDr. Jan Černý, CSc.

Cor Vasa 2011, 53(6-7):394-395  

Jako sedm statečných...

Doc. MUDr. Eliška Sovová, Ph.D., MBA

Cor Vasa 2011, 53(6-7):395  

K životnímu jubileu prof. MUDr. Lenky Špinarové, Ph.D., FESC

Prof. MUDr. Jiří Vítovec, CSc., FESC

Cor Vasa 2011, 53(6-7):396  

Blokátory kalciových kanálů v léčbě arteriální hypertenze

Cor Vasa 2011, 53(6-7):404-406  

4. ročník Rokitanského dne v Hradci Králové

Prof. MUDr. Radek Pudil, Ph.D.

Cor Vasa 2011, 53(6-7):406