Cor Vasa 2011, 53(6-7):328-332 | DOI: 10.33678/cor.2011.082

The effect of a biocompatible coated cardiopulmonary bypass system on fibrinogen levels as determined by the TEG Functional Fibrinogen method - preliminary results

Ivo Fluger1,*, Kateřina Maderová1, Martin Šimek1, Roman Hájek1, Vladimír Lonský1, Jana Zapletalová2
1 Kardiochirurgická klinika, Fakultní nemocnice Olomouc a Lékařská fakulta Univerzity Palackého, Olomouc
2 Ústav lékařské biofyziky, Lékařská fakulta Univerzity Palackého, Olomouc, Česká republika

When cardiopulmonary bypass (CPB) is used, the blood comes into contact with foreign surfaces. It causes an activation of numerous cascade and cell systems, including coagulation. To diminish this impact, various types of biocompatible coated surfaces have been developed. We studied the effect of heparin-coated CPB systems on the level and function of fibrinogen as measured by TEG, compared with non-coated systems. No statistically significant differences between both groups were revealed by comparing paired data.

Keywords: Biocompatible surface; Functional fibrinogen; TEG; Coagulation; Cardiopulmonary bypass

Published: June 1, 2011  Show citation

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Fluger I, Maderová K, Šimek M, Hájek R, Lonský V, Zapletalová J. The effect of a biocompatible coated cardiopulmonary bypass system on fibrinogen levels as determined by the TEG Functional Fibrinogen method - preliminary results. Cor Vasa. 2011;53(6-7):328-332. doi: 10.33678/cor.2011.082.
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