Analysis of arterial hypertension pharmacotherapy in patients with obstructive sleep apnea syndrome

Milan Sova, Eliška Sovová, Milada Hobzová, Karel Urbánek, Jana Zapletalová, Monika Kamasová, Denisa Barinová, Barbora Gottfriedová, Irena Kuca, Vítězslav Kolek

Cor Vasa 2015, 57(3):e157-e162 | DOI: 10.1016/j.crvasa.2015.03.011  

Introduction: Obstructive sleep apnea (OSA) is often connected with arterial hypertension and it could also be a cause of secondary hypertension. Treatment of arterial hypertension and optimal blood pressure level are important for prevention of cardiovascular complications. It is not well known how to treat patients with OSA and arterial hypertension. Also many patients with OSA suffer from metabolic syndrome which worsens their prognosis.Aim: The aim of our study was to assess arterial hypertension compensation in patients with metabolic syndrome and moderate to severe OSA and to analyze used pharmacotherapy.Materials and methods: 85 hypertensive...

The determinants of blood pressure response to exercise

Vladimír Tuka, Ján Rosa, Marika Dědinová, Martin Matoulek

Cor Vasa 2015, 57(3):e163-e167 | DOI: 10.1016/j.crvasa.2015.03.010  

Introduction: There is currently no consensus on the definition of normal BP (blood pressure) increase during exercise and thus of the exaggerated BP response to exercise. The aim of the present study was a description of the relationship between BP and work rate corrected by body weight on cycle ergometer. A secondary objective was to explore the possible components of this relationship.Materials and methods: An observational study with retrospective analysis of the BP data acquired during standard stress tests on cycle ergometer was performed. For the analysis each work rate was expressed corrected to the patient's body weight.Results: We...

Incidence and risk factors of delirium in patients after cardiac surgery: Modifiable and non-modifiable factors

František Sabol, Boris Bilý, Panagiotis Artemiou, Adrián Kolesár, Pavol Török, Miroslava Bilecová-Rabajdová, Peter Kolarčík, Ján Luczy

Cor Vasa 2015, 57(3):e168-e175 | DOI: 10.1016/j.crvasa.2015.01.004  

Background: Post cardiac surgery delirium is a severe complication. This study tried to evaluate the early postoperative delirium risk factors and to identify which of them can be modified in order to optimize perioperative management.Methods: It is a prospective observational study. Two hundred and fifty consecutive cardiac surgery patients took part in the study. Cardiac surgery, the anesthetic regiment and the postoperative management were standardized. The incidence and the risk factors of the postoperative delirium were analyzed by univariate and multivariate analysis. Delirium was assessed with screening scale - The Confusion Assessment Method...

Clinical impact of left atrial appendage resection versus preservation during surgical ablation of atrial fibrillation

Vojtěch Kurfirst, Bohuslav Kuta, Júlia Čanádyová, Aleš Mokráček

Cor Vasa 2015, 57(3):e176-e180 | DOI: 10.1016/j.crvasa.2015.03.007  

Introduction: Resection of left atrial appendage (LAA) during surgical ablation of atrial fibrillation may decrease the incidence of postoperative cerebrovascular events and increase the induction and maintenance of sinus rhythm (SR). This study evaluates the effect of LAA resection after the surgical ablation of atrial fibrillation.Materials and methods: A retrospective analysis was made of 599 patients who underwent surgical myocardial revascularization and/or valve surgery with concomitant surgical ablation of atrial fibrillation. The LAA was resected in 140 patients and preserved in 459 patients. Postoperative, 1-month and 1-year results were...

Endovascular management of coarctation of the aorta in adult patients

Jiří Novotný, Jan H. Peregrin

Cor Vasa 2015, 57(3):e181-e186 | DOI: 10.1016/j.crvasa.2015.03.008  

Background: Coarctation is a congenital heart defect with an incidence of 5-8%, more frequent in boys; however, the overwhelming majority of patients undergo surgery earlier as pediatric patients. Currently, the treatment of choice in adolescents and adults is endovascular management.Method: We used all three common catheter-based techniques: simple balloon dilatation, stent placement, and stent-graft placement. All treated patients underwent pre- and postprocedural CT angiography.Group of patients: Between 2004 and 2014, we treated a total of 10 patients with coarctation. They included seven men and three women, with a mean age of 41.1 (21-59)...

Cadmium-zinc-telluride SPECT scanners - New perspectives in nuclear cardiology

Vladimír Kincl, Adéla Drozdová, Jiří Vašina, Roman Panovský, Milan Kamínek

Cor Vasa 2015, 57(3):e214-e218 | DOI: 10.1016/j.crvasa.2015.01.001  

Nuclear cardiology is one of the most important non-invasive imaging methods in cardiac imaging. It makes possible primarily functional assessment of the heart with quantification of perfusion and systolic function. Development of new types of scanners for nuclear cardiology brings more possibilities in research and clinical practice. This paper describes a brief review of some applications of cadmium-zinc-telluride (CZT) scanners in comparison with conventional cameras.

Medical treatment of hypertrophic cardiomyopathy - What do we know about it today?

Pavel Gregor, Karol Čurila

Cor Vasa 2015, 57(3):e219-e224 | DOI: 10.1016/j.crvasa.2015.02.003  

Beta-blockers represent a cornerstone of the treatment of symptomatic hypertrophic cardiomyopathy - they are the first-line therapy for obstructive and non-obstructive forms. Sympathetic modulation leads to the deceleration of heart rate at rest and after exertion, and unconvincingly to the improvement of left ventricular diastolic function and obstruction. Medications include also nondihydropyridine calcium channel blockers without significant vasodilatory properties, i.e. verapamil and diltiazem. Other medications used are class IA antiarrhythmic drugs - disopyramide or cibenzoline, which can be administered to patients with obstructive forms when...

Summary of the 2014 ESC Guidelines on non-cardiac surgery: Cardiovascular assessment and management. Prepared by the Czech Society of Cardiology

Hana Skalická, Zuzana Moťovská, František Toušek

Cor Vasa 2015, 57(3):e190-e213 | DOI: 10.1016/j.crvasa.2015.02.008  

Repair of a partial anomalous venous return from the left lung in a patient after atrial septal defect closure

Vilém Rohn, David Janák, Jan Horák

Cor Vasa 2015, 57(3):e225-e227 | DOI: 10.1016/j.crvasa.2014.08.003  

We report a case of a successful surgical treatment of congenital heart defect in a 47-year-old man who experienced an atrial septal defect closure seven years ago. Nevertheless even after the operation he still suffered from increasing shortness of breath, which reached grade NYHA III last year. This state was caused by a partial anomalous venous return (PAPVR) from the left lung to the left brachiocephalic vein. This fact was overlooked during the first operation. Surgical treatment of newly diagnosed, at the time undifferentiated concomitant cardiac defect in the field of previous surgery requires a comprehensive assessment of the patient's condition...

Persistent left superior vena cava, absent right superior vena cava and coronary-bronchial fistula: The good, the bad and the ugly (case report and review of literature)

Jiří Plášek, Tomáš Veiser, David Šipula, Miroslav Homza

Cor Vasa 2015, 57(3):e228-e233 | DOI: 10.1016/j.crvasa.2014.11.001  

A 62-year-old Caucasian male presented with syncope during casual daily activity without preceding prodromes. During ECG Holter monitoring, we observed numerous asystolic pauses lasting >4 s due to sino-atrial blockade and sinus bradycardia. During pacemaker implantation, persistent left superior vena cava with agenesis of the right superior vena cava was diagnosed. Unproblematic placement of atrial lead was followed by challenging placement of the right ventricular lead. Anterior position with a sharp angulation to the right ventricular wall was achieved with excellent stimulation parameters. Transesophageal echocardiography confirmed the diagnosis...

Cardiotoxicity of yew

Ondřej Piskač, Jan Stříbrný, Hana Rakovcová, Martin Malý

Cor Vasa 2015, 57(3):e234-e238 | DOI: 10.1016/j.crvasa.2014.11.003  

The Common Yew (Taxus baccata) is an ornamental tree. The taxine alkaloids that are contained in yew berries, needles or bark are poisonous. The lethal dose for an adult is reported to be 50 g of yew needles. Patients who ingest a lethal dose frequently die due to cardiogenic shock, in spite of resuscitation efforts. Although no specific therapy exists, in some patients the asystole phase can be overcome by instituting extracorporeal membrane oxygen therapy (ECMO). Therapeutic procedures reported in the literature are only referred to in published case reports and it is not self-evident whether they have been effective or whether the patient had ingested...

An update of the expert consensus statement of the Czech Hypertension Society on renal denervation in resistant hypertension

Jan Filipovský, Václav Monhart, Jiří Widimský jr.

Cor Vasa 2015, 57(3):e187-e189 | DOI: 10.1016/j.crvasa.2015.01.003  

In the spring of 2012, the Czech Society of Cardiology and Czech Hypertension Society issued a joint expert consensus statement on catheter-based renal denervation (RDN) in the Czech Republic. On the basis of new information from the SYMPLICITY HTN-3, PRAGUE-15 and other studies, there is no reason to introduce RDN into clinical practice. New modalities for RDN, such as radiofrequency ablation, are investigated.

49. výroční sjezd Association for European Paediatric and Congenital Cardiology v Praze

Prof. MUDr. Jan Janoušek, Ph.D.

Cor Vasa 2015, 57(3):362 | DOI: 10.33678/cor.2015.033  

Rivaroxaban: napříč spektrem indikací a profilů pacientů

Zuzana Zafarová

Cor Vasa 2015, 57(3):363-365 | DOI: 10.33678/cor.2015.034  

Katetrizační a miniinvazivní zákroky na aortální a mitrální chlopni

MUDr. Zuzana Zafarová

Cor Vasa 2015, 57(3):367-369 | DOI: 10.33678/cor.2015.035  

Dabigatran v praxi - celosvětové setkání odborníků věnované antikoagulační léčbě

Cor Vasa 2015, 57(3):370-373 | DOI: 10.33678/cor.2015.036  

Účinnost a bezpečnost inhibitoru proprotein konvertázy subtilisin/kexin typu 9 alirocumabu u nemocných s vysokým kardiovaskulárním rizikem: studie ODYSSEY COMBO I

Michal Vrablík

Cor Vasa 2015, 57(3):377-380  

Zápis ze schůze výboru ČKS konané 13. ledna 2015 v Brně

P. Widimský, L. Klímová

Cor Vasa 2015, 57(3):382-383  

Moje vzpomínky na začátky Dětského kardiocentra v Praze

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2015, 57(3):374  

Urgentní medicína v klinické praxi lékaře

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2015, 57(3):375  

Zemřel prof. MUDr. Miloš Štejfa, DrSc., FESC (28. 5. 1929-20. 5. 2015)

Jiří Vítovec, Lenka Špinarová, Jindřich Špinar

Cor Vasa 2015, 57(3):384  

Editorial Board

Editorial board

Cor Vasa 2015, 57(3):i | DOI: 10.1016/S0010-8650(15)00057-0