Legislativa zakazující kouření ve všech uzavřených prostorách a pracovištích a výskyt akutních koronárních syndromů ve Skotsku

Jiří Widimský

Cor Vasa 2008, 50(10):364-365  

Primární hyperaldosteronismus: epidemie, anebo jen častá příčina sekundární hypertenze?

Jiří Widimský jr.

Cor Vasa 2008, 50(10):366-367  

The efficacy and safety of combination therapy with atorvastatin and tacrolimus in heart transplant recipients

Blanka Skalická, Ivan Málek, Yevheniya Vymětalová, Lenka Hošková, Mariana Podzimková, Josef Kautzner

Cor Vasa 2008, 50(10):368-372 | DOI: 10.33678/cor.2008.134  

Background: HMG-CoA inhibitors are a common part of standard drug regimen after orthotopic heart transplantation (OHTx). On the other hand, they are potentially dangerous as they could interact with cyclosporin A (CsA). The aim of this study was to evaluate the efficacy and safety of combination therapy with atorvastatin and tacrolimus (TAC) in heart transplant recipients.Methods: We followed a group of 31 OHTx patients with repeatedly documented plasma levels of total cholesterol above 5.5 mmol/L while on fluvastatin therapy. CsA was the main immunosuppressive drug. The patients were subsequently switched to a combination of TAC and atorvastatin...

Prognostic value of stress myocardial perfusion and left ventricular function imaging using single--photon emission tomography

Milan Kamínek, Iva Metelková, Miroslava Budíková, Eliška Sovová, Jan Lukl, Hana Študentová

Cor Vasa 2008, 50(10):373-377 | DOI: 10.33678/cor.2008.135  

Aim: The aim of this study was to assess the potential for risk stratification using quantitative perfusion and left ventri-cular function parameters provided by gated SPECT imaging.Methods: The study population comprised 402 patients who underwent stress SPECT followed by coronary angiography: 284 men, mean age 61 ± 10 years, 102 after previous myocardial infarction (MI), 182 after revascularization. A summed difference score (SDS), poststress and rest left ventricular ejection fraction (LVEF) and transient ischemic dilatation (TID) ratio were obtained through the use of 4D-MSPECT software. Postischemic left ventricular stunning was defined...

Evaluation of left ventricular function in patients treated for malignancy in childhood

Pavla Balcárková, Lubomír Elbl, Zuzana Nováková, Hana Hrstková, Jiří Vítovec, Jana Šťastná, Klára Krontorádová

Cor Vasa 2008, 50(10):378-384 | DOI: 10.33678/cor.2008.136  

Aim of study: To assess changes in left ventricular function in asymptomatic patients treated for malignancy in childhood.Methods: The study included 33 patients aged 16.7 ± 1.7 years examined 11.9 ± 2.4 years after the completion of anthra-cycline chemotherapy (A), and 13 patients aged 16.3 ± 2.0 years examined 9.5 ± 2.9 years after completed chemotherapy without antracyclines (NonA). A control group (K) included 64 healthy adolescents aged 16.8 ± 1.2 years. All adolescents were examined using echocardiography with blood pressure measurement. All values were compared between the subgroups.Results: When comparing...

Heart failure and atrial fibrillation

Růžena Lábrová, Jindřich Špinar

Cor Vasa 2008, 50(10):385-392 | DOI: 10.33678/cor.2008.137  

Heart failure and atrial fibrillation are often referred to as the epidemics of the 21st century. They are conditions characterized by an appreciably increasing incidence with increasing age - the typical patient is over 70 years old. The prerequisite for successful drug therapy of both conditions is effective oral anticoagulation and an individualized choice between rhythm versus rate control in an effort to prevent sudden cardiac death or progression of heart failure. Optimal therapy of heart failure should control symptoms and prevent the onset of new atrial fibrillation. The question whether to control rhythm or rate in the treatment of atrial...

Some aspects of the effect of the marathon race on the cardiovascular system

Josef Veselka

Cor Vasa 2008, 50(10):393-395 | DOI: 10.33678/cor.2008.138  

Multiple studies have documented transient cardiac dysfunction and provided biochemical evidence of cardiac injury (release of biomarkers) after finishing a marathon race. This case report describes a 43-year-old amateur marathon runner who finished a marathon race and subsequent echocardiographic examination revealed mild left ventricular diastolic dysfunction. Discussion is focused on the transient myocardial dysfunction and release of biomarkers after the completion of a marathon race.

Heart retransplantation for undiagnosed severe acute cellular rejection

Helena Bedáňová, Jan Černý, Erik Petrikovits, Pavel Studeník, Olga Janíčková, Jiří Ondrášek, Petr Němec, Lenka Špinarová, Alžběta Sirotková

Cor Vasa 2008, 50(10):396-398 | DOI: 10.33678/cor.2008.139  

Given the imbalance between the offer of and demand for donor hearts, heart retransplantation is a controversial "procedure"; on the other hand, retransplantation is often the only therapeutic option in the presence of heart graft failure. We report the case of a patient in whom even repeat endomyocardial biopsies failed to identify severe acute cellular rejection as the cause of heart graft failure.

Right heart failure as the first presentation of a malignancy

Iva Kociánová, Zuzana Moťovská, Blanka Rosová

Cor Vasa 2008, 50(10):399-402 | DOI: 10.33678/cor.2008.140  

This case report raises the question whether abdominal ultrasound belongs to standard diagnostic methods in patients with right heart failure of unknown etiology.A 79-year-old man was admitted to hospital because of progressive dyspnea and symptoms of right heart failure. Echocardiography demonstrated preserved left ventricular systolic function and pulmonary hypertension. The patient died on day 9 of hospitalization of fulminant right heart failure. Autopsy revealed papillary renal cell carcinoma in the right kidney. Microscopic examination of the lungs discovered disseminated tumor emboli within the small branches of the pulmonary artery. Pulmonary...

Jiří Widimský a kolektiv: Hypertenze

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2008, 50(10):K193  

Akutní proximální aortální disekce penetrující do levé síně, řešená urgentní Bentallovou operací

Marián Benčat, Martin Hutyra, Vladimír Lonský, Jan Václavík, Josef Novotný, Jan Lukl

Cor Vasa 2008, 50(10):403-404 | DOI: 10.33678/cor.2008.141  

Zpráva o účasti na Evropském kardiologickém kongresu ve dnech 30. 8.-3. 9. 2008

MUDr. Gabriela Dostálová

Cor Vasa 2008, 50(10):K189  

Na okraj výročního kongresu ESC

Jaroslav Hořejší

Cor Vasa 2008, 50(10):K182-188  

Roman Čerbák pětasedmdesátiletý

Cor Vasa 2008, 50(10):K190-191  

O ctižádostech předsedů III

Roman Čerbák

Cor Vasa 2008, 50(10):K180-181  

Vyšetření pulsu - zanedbaná možnost evidence

MUDr. Pavel Jerie

Cor Vasa 2008, 50(10):K194  

Kalendář odborných akcí

Cor Vasa 2008, 50(10):K195