Cor et Vasa, 2002 (vol. 43), issue 2

Original research articles

The value of pressure gradient measurement in iliac artery angioplasty

Jan H. Peregrin, Miloslav Roček, Dagmar Krajíčková, Jarmila Laštovičková, Jozef Kováč, Jiří Novotný, Boris Kožnar

Cor Vasa 2002, 43(2):56-60

Purpose:To identify the role of transstenotic pressure gradients in evaluating the outcome of percutaneous transluminal angioplasty (PTA) of iliac arteries. To determine the influence of pharmacological peripheral vasodilatation on the pressure gradient. To compare pressure gradients with angiographic stenosis evaluation. Material and methods:A total of 64 systolic transstenotic pressure gradients were evaluated in 37 patients (37 during angiographic examinations, 10 after PTA, and 20 after stent implantation). In 30 angiographic examinations, the gradient was measured at rest and after tolazoline-induced peripheral vasodilatation. Results:In...

Electroanatomical 3D mapping of the arrhythmogenic substrate and catheter- -based radiofrequency ablation of ventricular tachycardia using cooled catheters in patients after myocardial infarction-a pilot study

Petr Neužil, Miloš Táborský, Vivek Reddy, Lucie Šedivá, Roman Vopálka, Jan Petrů, Petr Niederle

Cor Vasa 2002, 43(2):62-71

Introduction:Ventricular tachycardia (VT) developing secondary to an ischemic arrhythmogenic substrate poses a substantial hemodynamic threat to most patients. Their morphology is multiple making "clinical tachycardia" difficult to define. As a result, the established and otherwise very effective mapping criteria applicable to an ongoing VT induced during an electrophysiological testing procedure often cannot be used. Method:The present study reports on the clinical use of electroanatomical three-dimensional (3D) mapping using a CARTOTM system involving the reconstruction of individual left ventricular maps (bipolar and unipolar...

Pre-transplant risk factors affecting early mortality following orthotopic heart transplantation

Helena Bedáňová, Jan Černý, Josef Nečas, Petr Němec, Jiří Ondrášek, Jaroslav Benedík, Marie Ošmerová, Olga Janíčková, Irena Kužmová

Cor Vasa 2002, 43(2):73-76

Aim:To identify the risk factors of early (30-day) mortality after orthotopic heart transplantation (OHT) with respect to the recipient and donor. Method:A retrospective study in 167 patients undergoing OHT, in particular a detailed analysis of data from patients dying within 30 days post-transplant (including their respective donors). Results:The identified risk factors of early mortality in deceased recipients included urgency status (p < 0.05), previous heart surgery (p < 0.001), increased pulmonary vascular resistance (p < 0.025), and an older mean age (p < 0.001). A low tissue compatibility...

Malignancies in patients after heart transplantation

Lenka Hošková, Ivan Málek, Mariana Podzimková, Vladimír Staněk, Jan Pirk, Martin Kment

Cor Vasa 2002, 43(2):77-80

Introduction:Malignancies occur 4-7 times more often in patients after heart transplantation than in the general population and tend to progress more rapidly. Long-term immunosuppressive therapy and recurrent infections make the immune system less capable of destroying potentially malignant cells. The study was designed to determine the incidence of tumors at different time intervals post-transplant and the pattern of tumor distribution. Methods:From 1984 through December 2000, a total of 419 heart transplant procedures (371 in men and 48 in women) were performed at the Institute for Clinical and Experimental Medicine. The...

Long-term development and current status of the smoking habits of the Czech population

Zdenka Škodová, Renata Cífková, Věra Adámková, Marie Jozífová, Věra Lánská, Eva Novozámská, Zdenka Petržílková, Markéta Plášková, Daniel Palouš, Ludmila Peterková, Markéta Micková-Galovcová, Martina Barátová

Cor Vasa 2002, 43(2):81-86

Aim:Tobacco smoking is a major risk factor of cancer and cardiovascular disease. Our study was designed to identify the current smoking habits of the population in nine districts of the Czech Republic, and to analyze, in six of these districts, the developmental trends in smoking prevalence in the 1985-2000/01 period by sex, age, and educational levels of the population. Study population and method:In 1985, 1988, and 1992, risk factor surveys were conducted in the districts of Benešov, Cheb, Chrudim, Jindřichův Hradec, Pardubice and Praha-východ; while the surveys in 1997/98 and 2000/01 included also the districts of Kroměříž,...

Case reports

Unusual location of the substrate of fascicular idiopathic left ventricular tachycardia

Miroslav J. Munclinger, Reventheran G. Pillay, Jai J. Patel, Abdul S. Mitha

Cor Vasa 2002, 43(2):87-90

A successful ablation of fascicular left ventricular tachycardia located on a false tendon in the left ventricle is presented. A high-frequency His-Purkinje potential was recorded along the fascicles as well as around the insertion and along the false tendon in sinus rhythm. The position of the mapping catheter was monitored by echocardiography. During tachycardia, early endocardial activation with an identical ECG pace map was recorded at the septum in the area of insertion, however, repeated attempts to ablate the tachycardia in this region failed. The earliest endocardial activation (V-QRS: -15 ms) preceded by a high- frequency Purkinje cell potential...

Temporary cyclosporin withdrawal in a patient after heart transplantation during chemotherapy for post-transplant lymphoproliferative disease

Mariana Podzimková, Ivan Málek, Petr Frídl, Tomáš Kozák

Cor Vasa 2002, 43(2):92-94

A patient undergoing orthotopic heart transplantation, performed in 1986, had post-transplant lymphoproliferative disease with two relapses. The disease became manifest in 1995, 9 years after surgery, with the first and second relapses occurring in 1999 and 2001, respectively. First-line therapy included CHOP combination therapy, to be replaced by the more aggressive Pro MACE Cyta BOM protocol after the first relapse. The second course of chemotherapy was associated with cyclosporin withdrawal. No signs of rejection were identified in any of the biopsy specimens obtained from the patient.

Short communication

Aortic valve replacement with a Shelhigh SuperStentless bioprosthesis

Tomáš Honěk, Jaroslav Špatenka, Pavel Šebesta, Josef Veselka, Jana Páleníčková, Tomáš Vymazal, Karel Cvachovec, Jaroslav Hlubocký, Milan Horn

Cor Vasa 2002, 43(2):96-98

Aortic valve replacement with a bioprosthesis is currently indicated in elderly individuals. Patients with a bioprosthesis do not require anticoagulation therapy. The advantages of stentless prostheses include a low transvalvular gradient, especially so in patients with a narrow aortic annulus, while the drawbacks include more complex implantation. A new model of prosthesis, the Shelhigh SuperStentless, allows standard safe single-layer implantation. The authors describe their favorable early results in 30 patients operated on for severe aortic stenosis.

Valve involvement during treatment with anorectic agents: echocardiographic follow-up

Hana Línková, Jiří Krupička, David Pohlreich, Kardiocentrum

Cor Vasa 2002, 43(2):99-100

Using echocardiography, valvular structural changes, demonstrated by other authors after long-term treatment, were assessed in a series of our 28 patients treated with serotoninergic anorectic agents. Major valvular regurgitation was not observed in any of our patients. This is most likely to be due to the generally lower dose of the anorectic and shorter duration of therapy compared with large groups evaluated in international studies.


Cor et Vasa

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