Cor et Vasa, 2003 (vol. 44), issue 11

Original research articles

A comparison of hypertension control and the risk profile of hypertensives in the general population and in a specialist center

Marie Jozífová, Renata Cífková, Zdenka Škodová, Eva Novozámská, Věra Adámková, Markéta Plášková, Ludmila Peterková, Věra Lánská, Rudolf Poledne

Cor Vasa 2003, 44(11):533-541

Arterial hypertension affects more than a third of the middle-aged Czech population, with effective hypertension control obtained in less than 20% of hypertensives. Aim:To compare hypertension control and the risk profile of drug-treated hypertensives of a population sample with those of a group of hypertensives treated at a specialist center, the Department of Preventive Cardiology (DPC) of the Institute for Clinical and Experimental Medicine (IKEM). Method:A 1% random population sample aged 25-64 years (1,684 men and 1,763 women; respondence rates of 63.8% and 64.8 %, respectively) was examined in nine districts of the...

The in-hospital course of acute myocardial infarction in the Czech Republic. A myocardial infarction registry in PRAGUE-1

František Bednář, Petr Widimský, Pavel Třeštík, Petr Povolný, David Vencour, Miroslava Patočková, Ondřej Čermák, Radovan Sís, Venuše Šmejkalová, lékaři nemocnic spolupracujících na studii PRAGUE-1

Cor Vasa 2003, 44(11):543-549

Aim of study:Analysis of the myocardial infarction registry of the PRAGUE-1 (PRimary Angioplasty in patients transferred from General community hospitals to specialized PCI Units with or without Emergency thrombolysis) study. Method:A retrospective analysis of the registry of all patients with myocardial infarction admitted, from June 1997 through March 1999, to 17 general community hospitals without a catheterization room and cooperating in PRAGUE-1. Results:Overall, 2,512 myocardial infarction (MI) patients with a mean age of 67 years, and men making up 58%, were admitted. Final diagnoses of Q-wave MI were...

Case reports

PTCA of left main occlusion in a patient in cardiogenic shock complicating anterior myocardial infarction. Two-year follow-up

Sławomir Dobrzycki, Przemysław Prokopczuk, Wacław Kochman, Bronisław Czech, Paweł Kralisz, Ewa Kucewicz-Czech, Grzegorz Juszczyk, Konrad Nowak

Cor Vasa 2003, 44(11):551-555

Cardiogenic shock is the most serious hemodynamic complication of acute myocardial infarction (AMI). Currently, it occurs in 5-10% of patients with AMI. Cardiogenic shock results in high mortality, ranging from 35% up to 100%, depending on the treatment used. Most often, it occurs in cases of acute occlusion of the left anterior descending artery (LAD) or the left main coronary artery (LMCA), leading to myocardial infarction that involves large areas of the left ventricle. Nevertheless, acute occlusion of the proximal part of a dominant right coronary artery or circumflex artery may also be the cause of this complication. This paper reports successful...

35 years after acute myocardial infarction in pregnancy

Iveta Šimková, Stanislav Cagáň

Cor Vasa 2003, 44(11):557-561

Acute myocardial infarction in pregnancy is very rare. Prognosis is poor in patients under the age of 35 years suffering a myocardial infarction in the third trimester, and delivering within 2 weeks of her infarction. We describe the case of a 57-year-old asymptomatic woman who developed a myocardial infarction during pregnancy 35 years ago. We analyze her acute as well as long-term follow-up. A review of the recent literature follows. Unique data regarding this topic and published in the Czech- and Slovak-language literature to date are also provided.

Short communication

Results of the INVEST study in the context of guidelines for the treatment of hypertension

Otto Mayer

Cor Vasa 2003, 44(11):562-564

It is still unclear whether the protective effect of antihypertensive treatment should be enhanced using more aggressive treatment strategies to achieve target values or, rather, using drugs, which control a broader spectrum of risk factors. Moreover, EUROASPIRE II demonstrated that half of patients with hypertension and coronary heart disease (CHD) are receiving unsatisfactory treatment. The recently published results of the INVEST study showed an equivalent protective effect in high-risk hypertensive patients with overt CHD using two different treatment strategies. The study, enrolling more than 22,000 patients, was designed to determine the number...

Myocardial injury and full reversibility - will we identify the responsible gene and will it serve us?

Jan Šochman

Cor Vasa 2003, 44(11):565-566

As a dogma in cardiology, it is still believed that severely damaged myocardial structures in adult humans will not get repaired naturally. There have been attempts at modified regeneration using transformed and implanted stem or embryonic cells. However, a piece of evidence from the animal kingdom suggests the potential for full regeneration: a new mutation of the mitotic Mps 1 kinase responsible for complete replacement of absent myocardial structures. This is an exciting finding that provides support to concepts based on the replacement of lost tissue, lost structures, and lost function.

Percutaneous bioprosthesis implantation into the aortic position

Ingrid Homolová, Josef Veselka

Cor Vasa 2003, 44(11):567-568

The authors inform on their initial literary experience with percutaneous biological valve prosthesis implantation into the aortic position. To date, this therapeutic option has been tested just in a few patients, yet it may represent an exciting trend and an alternative to surgery, which is the gold standard in these indications.


Cor et Vasa

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