Cor et Vasa, 2010 (vol. 52), Suppl.

75 let kardiologie na Královských Vinohradech

Jana Málková, Zbyněk Straka, Pavel Gregor, Martin Herold, Martin Bernat, Miroslav Bulvas, Petr Widimský

Cor Vasa 2010, 52(Suppl.):7-11 | DOI: 10.33678/cor.2010.196

Arrhythmogenic left ventricular dysplasia

Petr Widimský, Rostislav Polášek

Cor Vasa 2010, 52(Suppl.):12-14 | DOI: 10.33678/cor.2010.197

Arrhythmogenic right ventricular dysplasia is a rare, but well-characterized disease with a high risk of sudden death. This case report describes an unusual case of a young woman with severe syncope due to the arhythmogenic dysplasia of the left ventricle or, possibly, interventricular septum.

Measuring of platelet activity and efficacy of antiplatelet therapy

Pavel Osmančík, Petra Paulů, Petr Toušek, František Bednář, Zuzana Moťovská, Petr Widimský

Cor Vasa 2010, 52(Suppl.):15-20 | DOI: 10.33678/cor.2010.198

The aim of this paper is an overview of current options for measuring platelet activity and efficacy of antiplatelet therapy. The second part of the paper offers examples based on the authors' own experience. Particular attention is given to measurement of the effect of ADP antagonists.

Treatment of ST elevation acute myocardial infarction in Europe

Petr Widimský, Jiří Knot

Cor Vasa 2010, 52(Suppl.):22-23 | DOI: 10.33678/cor.2010.199

The availability and mode of reperfusion therapy for ST elevation acute myocardial infarction (STEMI) vary largely among European countries. This review article brings recent published data including experience from the best practice countries.The mean annual incidence of hospital admission for any acute myocardial infarction in Europe is 1,934 patients/mil. pop., 796 of them are STEMI. Primary PCI is the dominant reperfusion strategy in two thirds of Europe, while one third of Europe is still using thrombolysis as the dominant reperfusion strategy. These "thrombolytic" countries leave 46% of STEMI patients without any reperfusion therapy while,...

Antithrombotic therapy in patients at risk for coronary stent thrombosis undergoing non-cardiac surgery

Zuzana Moťovská, Petr Widimský

Cor Vasa 2010, 52(Suppl.):25-30 | DOI: 10.33678/cor.2010.200

Percutaneous coronary interventions have become the most commonly performed coronary revascularization procedures. At the same time, the probability has been increased that patients with intracoronary stents will have to undergo surgery. We can project that, in the Czech Republic, one thousand patients undergo non-cardiac surgery within six months of stent implantation annually. Two serious consequences emerge from this situation: (i) stent thrombosis in relation to discontinuation of antiplatelet therapy, and (ii) major bleeding in relation to continuation of antiplatelet therapy. The best solution to overcome the risks resulting from surgery performed...

Percutaneous coronary intervention in a cheerful, one-hundred-year-old patient with acute coronary syndrome

Petr Widimský, Viktor Kočka

Cor Vasa 2010, 52(Suppl.):31-32 | DOI: 10.33678/cor.2010.201

The absence of an age limit as a PCI contraindication is illustrated in the case of a 100-year-old female patient with acute coronary syndrome, who gained benefit from interventional treatment.

Tachycardia-induced cardiomyopathy

Pavel Gregor

Cor Vasa 2010, 52(Suppl.):34-36 | DOI: 10.33678/cor.2010.202

The paper is an overview of various aspects of tachycardia-induced cardiomyopathy, examining its controversial history but, primarily, current concepts regarding its etiology, pathogenesis, clinical picture, diagnosis, and therapy. Special emphasis is placed on issues related to the differential diagnosis of this most particular clinical entity whose perception has changed substantially in recent years.

Exercise echocardiography in the diagnosis of heart valve disease

Hana Línková, Michaela Rýzlová, Tomáš Indruch, Robert Petr, Jiří Karásek

Cor Vasa 2010, 52(Suppl.):37-42 | DOI: 10.33678/cor.2010.203

This review article summarizes current perspectives regarding the use of exercise echocardiography in diagnosing heart valve disease, particularly in asymptomatic, already hemodynamically significant heart valve disease where these tests may help to make a decision regarding future therapeutic options and timely surgical management.The paper examines the potential uses of exercise testing in individual, most frequent types of heart valve disease in adult age.

Infections of cardiac implantable electronic devices and their prevention

Dalibor Heřman, Pavel Osmančík, Petr Štros, Jiří Kletenský, Stanislav Hrdlička, Martin Herold

Cor Vasa 2010, 52(Suppl.):44-47 | DOI: 10.33678/cor.2010.204

The last quarter of the past century has seen exponential growth in implantable electronic device use. The rate of infection after implantation of these devices is low, but clinically important. Appropriate diagnostic and therapeutic procedures are necessary for proper management of these complications.

Fibrinolytic inhibitors in cardiac surgery - a view from the end of the first decade of the new millennium

Tomáš Vaněk, Ján Špegár, Jana Šnircová

Cor Vasa 2010, 52(Suppl.):48-51 | DOI: 10.33678/cor.2010.205

Preventive application of fibrinolytic inhibitors in cardiac surgery has been used to reduce perioperative blood loss and transfusion requirements since the 1980s. The article describes the history of introducing aprotinin into practice and deals with the circumstances leading to its recent withdrawal from the pharmaceutical market. It briefly summarizes the current view on synthetic lysine analogs both in cardiac surgery and other fields of surgery.

Aspirin resistance after coronary artery bypass grafting

František Bednář, Pavel Osmančík, Tomáš Vaněk, Petr Widimský

Cor Vasa 2010, 52(Suppl.):52-58 | DOI: 10.33678/cor.2010.206

Aspirin administration after surgical myocardial revascularization improves not only early patency, particularly that of the venous grafts but, also, and more importantly, it significantly improves clinical postoperative outcomes.Several recent papers have consistently reported an inadequate inhibitory effect of aspirin on platelet function in the early postoperative period, giving rise to what is now referred to as acquired aspirin insufficiency (resistance). The paper is an extensive overview of current concepts regarding the issue including its pathogenesis, diagnosis, and clinical relevance. The paper includes a list of the authors' own publications...

Carotid stenting in patients at high risk for endarterectomy

Miroslav Bulvas, Zuzana Sommerová, Renata Urbanová, Pavel Kraml, Filip Roháč, Tomáš Indruch

Cor Vasa 2010, 52(Suppl.):59-64 | DOI: 10.33678/cor.2010.207

Aim: The aim of the study was to evaluate technical success, safety and restenosis rate of carotid artery stenting in patients at high risk for carotid endarterectomy.Methods: Between October 1995 and December 2009, a total of 505 patients (541 carotid artery lesions) underwent carotid stenting. At least one risk factor for surgery (serious concomitant disease, contralateral carotid occlusion, restenosis after endarterectomy, neck radiotherapy, high stenosis location) was present in every patient. One hundred and seven stenoses (39%) were symptomatic. Thirty three balloon-expandable and 509 self-expandable stents were implanted.Results: Technical...

The endoscopic MAZE procedure - minimally invasive surgical treatment of isolated atrial fibrillation

Zbyněk Straka, Petr Budera, Pavel Osmančík, Martin Herold, Petr Brůček, Tomáš Vaněk

Cor Vasa 2010, 52(Suppl.):66-69 | DOI: 10.33678/cor.2010.208

Aim: The MAZE procedure belongs to the most effective options in the management of atrial fibrillation. Given its technical complexity and the need for extracorporeal circulation, it has been performed almost exclusively as a procedure combined with heart valve surgery or bypass to date. This paper presents our initial experience with the endoscopic MAZE procedure for isolated atrial fibrillation.Method: Two 10-mm and one 5-mm ports were inserted into the right hemithorax. The pericardium was incised longitudinally above the course of the phrenic nerve. Blunt trimming of the point whereby the vena cava superior passes through the pericardium was...

Transcatheter aortic valve implantation (TAVI) using the CoreValve prosthesis - initial experience in Královské Vinohrady University Hospital, advantages and pitfalls of the new method

Viktor Kočka, Petr Widimský, Petr Toušek, Pavel Červinka, František Bednář, Hana Línková, Michaela Rýzlová, Marek Laboš, Jaroslav Ulman, Karel Jirásek, Zbyněk Straka

Cor Vasa 2010, 52(Suppl.):70-75 | DOI: 10.33678/cor.2010.209

Introduction: Aortic stenosis is the most common type of valvular heart disease in adulthood and transcatheter aortic valve implantation (TAVI) is a new, evolving alternative to standard surgical aortic valve replacement, suitable for high surgical risk patients. We present our initial experience with this method.Method: The third generation of a self expanding CoreValve Revalving 18 Fr. valve is made up of a nitinol frame and a bioprosthetic valve from the porcine pericardium. We describe the course of the procedure step by step. From April 2009 to January 2010, we performed the TAVI procedure in 17 patients with severe symptomatic aortic stenoses....

Echocardiography in intensive care

Jaroslav Ulman

Cor Vasa 2010, 52(Suppl.):76-84 | DOI: 10.33678/cor.2010.210

This is a review article addressing the current position and potential of echocardiography in intensive medicine, focusing primarily on non-invasive hemodynamic examination.

The incidence of right bundle branch block in acute myocardial infarction

Filip Roháč, Jiří Knot, Alena Lorencová, Petr Widimský

Cor Vasa 2010, 52(Suppl.):85-87 | DOI: 10.33678/cor.2010.211

This study is based on information in a registry including data of patients with acute myocardial infarction (AMI) and hospitalized in our heart center together with another seven heart centers in the Czech Republic and abroad. The paper is the first to present part of the results of an analysis of data obtained from the patients. Using a group of patients with AMI, we have determined the current incidence of bundle branch block in this subpopulation. Patients' characteristics and mortality including in-hospital course and mortality were compared.