Od interny ke kardiologii, od kardiologie ke kardiovaskulární medicíně

Josef Veselka

Cor Vasa 2010, 52(7-8):392  

Balloon aortic valvuloplasty in high-risk patients with aortic stenosis

Jiří Fiedler, Kateřina Linhartová, Petr Hájek, Martin Malý, David Zemánek, Radka Adlová, Josef Veselka

Cor Vasa 2010, 52(7-8):413-417 | DOI: 10.33678/cor.2010.113  

Aim: To evaluate the outcome of balloon aortic valvuloplasty (BAV) in high-risk patients and severely symptomatic patients with calcified aortic stenosis.Method: Our group of patients included 34 individuals with a mean age of 80.8 ± 6.0 years who, because of their ineligibility for surgical aortic valve replacement (AVR) had 35 BAV procedures for progressive symptomatology in NYHA Classes III and IV. A total of eight procedures were performed using two-balloon catheters, and 27 procedures using single balloon catheters, with subsequent division of patients into corresponding subgroups (2B and 1B). While, in one case, the procedure was complemented...

The risk of pseudoaneurysm formation after elective angiography - an analysis of data of 498 consecutive patients

Martin Malý, Marek Šramko, Petra Zimolová, Pavel Stanka, Petr Hájek, David Zemánek, Lucie Martinkovičová, David Tesař, Josef Veselka

Cor Vasa 2010, 52(7-8):418-422 | DOI: 10.33678/cor.2010.114  

Aim: We analyzed the data of a series of 498 consecutive patients undergoing transfemoral elective angiography. The aims of our study were (a) to determine the incidence of pseudoaneurysms post-catheterization in our centre, (b) to analyze the profile of patients examined because of this complication.Patients and methods: Data of a total of 498 patients with a mean age of 65 ± 12 years and mean body mas index (BMI) of 28.4 ± 4.8 were analyzed. Seventy percent of patients were men (n = 347). Sixty-nine percent of patients (n = 343) had a history of coronary heart disease; 78% (n = 389) arterial hypertension; 36% of patients (n = 178)...

Cardiac resynchronisation in congenital heart disease

Jan Janoušek

Cor Vasa 2010, 52(7-8):424-430 | DOI: 10.33678/cor.2010.115  

Use of intravascular ultrasound in procedures involving the left main coronary artery

David Zemánek, Petr Hájek, Josef Veselka

Cor Vasa 2010, 52(7-8):431-436 | DOI: 10.33678/cor.2010.116  

Intravascular ultrasound (IVUS) is a method which has no alternative in catheter-based procedures and in the management of left main coronary artery stenosis. Proper assessment of the ultrasound finding is critical for selecting the most appropriate therapeutic option ensuring optimal outcomes. The paper is an overview of current concepts regarding the use of this method in interventional cardiology and this particular indication.

Peripheral artery disease: what is the best approach? The diagnostic and therapeutic algorithm for clinical practice

Petra Zimolová

Cor Vasa 2010, 52(7-8):437-440 | DOI: 10.33678/cor.2010.117  

Though a major cause of morbidity in the developed countries, peripheral arterial disease (PAD) belongs to conditions not receiving adequate attention in terms of its prevention, diagnosis, and treatment. A thorough history, proper timing and interpretation of results of examination combined with selection of appropriate therapy may significantly reduce the overall risk of cardiovascular events. At the same time, PAD is a marker of coronary and cerebral atherosclerosis.

Ventricular arrhythmias and sudden death in hypertrophic cardiomyopathy

Václav Durdil

Cor Vasa 2010, 52(7-8):441-446 | DOI: 10.33678/cor.2010.118  

Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary heart disease. Clinical features of the disease include ventricular arrhythmias. The pathogenesis of ventricular arrhythmias in HCM is multifactorial, with less severe forms of ventricular ectopy and non-sustained ventricular tachycardia being the most common finding. A proportion of patients is at increased risk of sudden death secondary to sustained ventricular arrhythmia or ventricular fibrillation. The mainstay of care of HCM patients is identification of these groups at risk and subsequent prevention of sudden death using the implantable cardioverter-defibrillator (ICD). Those with...

Timing and selection of the type of revascularization procedure in acute coronary syndrome without ST-segment elevation with multivessel coronary artery disease

Petr Hájek

Cor Vasa 2010, 52(7-8):447-452 | DOI: 10.33678/cor.2010.119  

Most patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) are treated with success by early percutaneous coronary intervention (PCI). In patients with multivessel coronary artery disease, selection of proper timing and type of revascularization procedure may prove to be difficult. Critical considerations in this context include the patient's clinical status, their risk profile, nature, and extent of coronary involvement. The pivotal role in this process is played by the interventional cardiologist assessing the findings on the coronary arteries. Any attempted treatment of the culprit lesion may significantly affect the type of...

Pregnancy-associated plasma protein-A in the pathophysiology, diagnosis, and prognosis of coronary heart disease

Petr Hájek, Milan Macek

Cor Vasa 2010, 52(7-8):453-457 | DOI: 10.33678/cor.2010.120  

Pregnancy-associated plasma protein-A (PAPP-A) is a potential marker of the vulnerable plaque. Given its known pathophysiological properties, it can be theoretically used not only in the early diagnosis of acute coronary syndrome (ACS) and its prognosis but, also, in the risk stratification of patients with no signs of coronary disease. A critical factor in deciding whether PAPP-A determination becomes part of routine clinical practice or fall into oblivion as did a host of other originally promising markers will be whether various aspects of this quick and accurate technique of determination become widely available. However, even if not eventually...

The pulmonary catheter - to use or not to use?

David Alan, Jiří Vejvoda

Cor Vasa 2010, 52(7-8):458-460 | DOI: 10.33678/cor.2010.121  

The role of the pulmonary artery catheter (PAC) or the Swan-Ganz catheter in the monitoring and management of the critically ill patient has not yet been conclusively defined. Despite the initial excessive enthusiasm in the 1970s as well as efforts seeking a moratorium in the 1980s, and the recently completed multicenter, randomized studies, a beneficial effect on morbidity and mortality of its use in the above population of patients has not been clearly demonstrated to date. The aim of our study was to provide, using relevant publications and our own clinical experience, a rationale for PAC use in specific serious clinical circumstances.

Not all syncopes are the same or what ictal asystole is

Lucie Riedlbauchová, Hana Krijtová, Petr Marusič, Václav Durdil, Jan Janoušek, Josef Veselka

Cor Vasa 2010, 52(7-8):461-464 | DOI: 10.33678/cor.2010.122  

Syncope and epileptic seizure are frequent causes of transient loss of consciousness. In some cases, it may be somewhat difficult to distinguish one from the other despite the different pathophysiological mechanisms behind each entity. However, in some cases, an epileptic seizure may eventually result in a syncope secondary to the development of significant bradycardia/asystole induced by the epileptic activity. This phenomenon, referred to as ictal asystole, is a potentially dangerous entity as it seems it might be a cause of sudden death in epileptic patients. The aim of this case report describing two patients examined in our department and diagnosed...

Catheterization closure of patent ductus arteriosus with Amplatz ductal occluder of a new generation in an adult patient

Martin Malý, Kateřina Linhartová, Petr Hájek, Josef Veselka

Cor Vasa 2010, 52(7-8):467-469 | DOI: 10.33678/cor.2010.123  

Patent ductus arteriosus is a persistent communication from the time of the fetal circulation between the aorta and the pulmonary artery. Unoperated patients may present with left-to-right shunt, volume overload of the left heart structures, pulmonary hypertension and the risk of endarteritis. If the ductus is large, there is a risk of development of Eisenmenger's physiology. The treatment option in newborns is surgical ligation, in adults the option is almost exclusively catheter-based closure. Catheter-based closure is possible with the use of coils or the Amplatz ductal occluder. In our paper, we report the successful transfemoral closure of a patent...

Katetrizační implantace aortální chlopně - multimodální zobrazení

Kateřina Linhartová, Martin Malý, Theodor Adla, Josef Veselka

Cor Vasa 2010, 52(7-8):470-471 | DOI: 10.33678/cor.2010.124  

Pracovní skupina srdeční selhání na XVIII. výročním sjezdu ČKS 2010

Jiří Vítovec, Lenka Špinarová, Lenka Hošková, Ondřej Ludka, za Pracovní skupinu srdeční selhání

Cor Vasa 2010, 52(7-8):475-476 | DOI: 10.33678/cor.2010.127  

Mezinárodní konference Pulmonary Circulation pořádaná Českou kardiologickou společností pod záštitou European Society of Cardiology a European Respiratory Society

Prof. MUDr. Michael Aschermann, DrSc., FESC, FACC

Cor Vasa 2010, 52(7-8):477-478 | DOI: 10.33678/cor.2010.128  

Zápis ze schůze výboru ČKS konané dne 13. května 2010 v Brně; Zápis z valné hromady ČKS konané dne 16. května 2010 v Brně

Cor Vasa 2010, 52(7-8):480  

The diagnosis and treatment of the most common form of restrictive cardiomyopathy: cardiac amyloidosis

Kateřina Linhartová

Cor Vasa 2010, 52(7-8):393-396 | DOI: 10.33678/cor.2010.106  

The most common restrictive cardiomyopathy is light-chain (AL) amyloidosis with an estimated prevalence of 8-10/1 mil. pop. The clinical picture is a combination of non-specific general symptoms with presentations of heart failure. The principal diagnostic method is echocardiography showing myocardial wall thickening and increased stiffness leading to left ventricular diastolic dysfunction. The gold standard is histologic evidence of amyloid with its immunohistochemical or immuno-electron microscope typing. Treatment is performed in close collaboration with a department of hematology, or even there, and is designed to inhibit the formation of amyloidogenic...

Tachycardia-induced cardiomyopathy

Lucie Riedlbauchová

Cor Vasa 2010, 52(7-8):397-398 | DOI: 10.33678/cor.2010.107  

Tachycardia-induced cardiomyopathy is characterized by the presence of systolic ventricular dysfunction and dilatation with clinical presentation of heart failure in patients with chronic tachyarrhythmias. A typical feature of the disease is partial or full reversibility of functional and structural alterations upon adequate therapy. A practical approach to the management of the tachycardia-induced cardiomyopathy includes 1) control of the tachyarrhythmia as the main pathophysiological factor behind the development and progression of the disease, and 2) management of heart failure. Most importantly, every effort should be made to restore a normal heart rate.

The genetics of cardiomyopathies

Pavol Tomašov

Cor Vasa 2010, 52(7-8):399-402 | DOI: 10.33678/cor.2010.108  

Cardiomyopathies make up a heterogeneous group of diseases with structural or functional myocardial impairment in the absence of an ischemic or hemodynamic insult capable of inducing this impairment. As a considerable proportion of cardiomyopathies is genetically mediated, they tend to occur more often in family members. The heritability of cardiomyopathy exhibits large genotype and phenotype variability and often incomplete penetrance. New concepts in the field of genetics of cardiomyopathies have helped to partly clarify the etiopathogenesis of these diseases and have become part of new classification systems of myocardial diseases. The most important...

Diagnosis and treatment of left ventricular non-compaction cardiomyopathy

Jiří Fiedler

Cor Vasa 2010, 52(7-8):403-404 | DOI: 10.33678/cor.2010.109  

Left ventricular non-compaction (LVNC) cardiomyopathy is a heterogeneous and relatively rare group of heart disease with the dominant feature being marked non-compactness of the myocardial luminal layer of some left ventricular segments. Its diagnosis is established by echocardiography, with the finding dominated by abnormal, appreciably prominent trabecularization of the left ventricular myocardium, particularly left ventricular postero-lateral segments with deep recessions. Treatment is governed by the same rules as with dilated cardiomyopathy.

Arrhythmogenic right ventricular cardiomyopathy

Jan Krejčí

Cor Vasa 2010, 52(7-8):405-408 | DOI: 10.33678/cor.2010.110  

Arrhythmogenic right ventricular cardiomyopathy is a genetically-linked condition characterized by loss of the myocardium, particularly that of the right ventricle, to be replaced by adipose and fibrous tissue. The clinical picture is dominated by arrhythmias, with most patients dying suddenly. The diagnosis is based on search for the presence of major and minor criteria. Principal methods of examination include electrocardiography, Holter ECG monitoring, echocardiography, magnetic resonance imaging and, possibly, other methods. The key therapeutic consideration is prevention of sudden death, that is, management of arrhythmias and, most importantly,...

The diagnosis and management of hypertrophic cardiomyopathy

Josef Veselka

Cor Vasa 2010, 52(7-8):409-410 | DOI: 10.33678/cor.2010.111  

Hypertrophic cardiomyopathy (HCM) is characterized by a thickened myocardium or increased cardiac mass in the absence of an underlying condition such as arterial hypertension or heart valve disease that may have caused this abnormity. About half to two thirds of HCM patients have intraventricular obstruction, most often subaortic one. The most common diagnostic tool is echocardiography. Pharmacotherapy is only initiated in symptomatic patients. Non-responders with obstructive forms of HCM may have myectomy or alcohol septal ablation. Patients with risk factors for sudden death have cardioverter-defibrillator devices implanted.

Dilated cardiomyopathy

David Zemánek

Cor Vasa 2010, 52(7-8):411-412 | DOI: 10.33678/cor.2010.112  

Dilated cardiomyopathy (DCM) is a relatively frequent myocardial disease. The paper provides a clear overview of the diagnostic methods used with this condition. The final part examines current options in the treatment of DCM including pharmacological and non-pharmacological therapy.

Alle Menschen werden Brüder. Všichni lidé se stanou bratry

Prof. MUDr. Roman Čerbák, CSc.

Cor Vasa 2010, 52(7-8):473  

Jindřich Špinar padesátníkem

Prof. MUDr. Michael Aschermann, DrSc., FESC, FACC

Cor Vasa 2010, 52(7-8):474  

Kalendář odborných akcí

Cor Vasa 2010, 52(7-8):478  

Česká kardiologická společnost udělila zlatou medaili profesora Libenského

Prof. MUDr. Michael Aschermann, DrSc., FESC, FACC

Cor Vasa 2010, 52(7-8):479