Cor Vasa 2011, 53(12):698-702 | DOI: 10.33678/cor.2011.173

Prognostic value of coronary artery calcium score in combination with cardiac stress sigle-photon emission tomography imaging in an asymptomatic population

Miroslava Budíková1, Milan Kamínek1,2,*, Eliška Sovová3, Markéta Kaletová3, Iva Metelková1, Lenka Henzlová1, Eva Buriánková1, Radim Formánek1
1 Klinika nukleární medicíny, Fakultní nemocnice Olomouc a Lékařská fakulta Univerzity Palackého, Olomouc
2 Mezinárodní centrum klinického výzkumu - Centrum molekulárního zobrazování, Fakultní nemocnice u sv. Anny, Brno
3 I. interní klinika, Fakultní nemocnice Olomouc, a Lékařská fakulta Univerzity Palackého, Olomouc Česká republika

Aim: The aim of this study was to investigate the prognostic value of coronary artery calcium (CAC) score in combination with cardiac stress sigle-photon emission tomography (SPECT) imaging in an asymptomatic population.

Methods: One hundred twenty-eight consecutive asymptomatic patients (79 men, mean age 54±10 years, 25 with diabetes) underwent stress cardiac gated SPECT imaging and CT assessment of CAC score. Perfusion summed stress and difference score (SSS and SDS, resp.), the left ventricular ejection fraction (LVEF) and end-diastolic/end-systolic volumes (EDV/ESV) were automatically calculated using 4D-MSPECT. Cardiac event was defined as either cardiac death, nonfatal myocardial infarction (MI), or conditions requiring coronary revascularization.

Results: During an average follow-up of 17±9 months, two patients had nonfatal MI, and revascularization was required in 8 patients. In the subgroup of 10 patients with cardiac events, the observed parameters was significantly worse than in patients without cardiac event concerning perfusion (SSS 10±12 vs. 1±0 and SDS 6±9 vs. 0±1, P

Keywords: Cardiac gated SPECT; Coronary artery calcium score (CAC); Risk stratification

Published: December 1, 2011  Show citation

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Budíková M, Kamínek M, Sovová E, Kaletová M, Metelková I, Henzlová L, et al.. Prognostic value of coronary artery calcium score in combination with cardiac stress sigle-photon emission tomography imaging in an asymptomatic population. Cor Vasa. 2011;53(12):698-702. doi: 10.33678/cor.2011.173.
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