Cor Vasa 2007, 49(11):416-425 | DOI: 10.33678/cor.2007.144

The long QT syndrome

Tomáš Novotný
Interní kardiologická klinika, Fakultní nemocnice Brno, Brno, Česká republika

The long QT syndrome is characterized by QT interval prolongation and increased risk of malignant arrhythmias, which can cause syncope or even sudden death. A typical feature is absence of structural cardiac disease. The article summarizes the most recent information on the syndrome "from cell to bedside": pathophysiology at molecular and cellular levels, clinical diagnosis and the current recommended therapeutic approaches. The acquired long QT syndrome and other hereditary arrhythmic syndromes are also briefly mentioned. In conclusion, the contribution of long QT syndrome research to the issue of sudden cardiac death in the general population is emphasized.

Keywords: Gene; Ion channel; Sudden cardiac death; Long QT syndrome

Published: November 1, 2007  Show citation

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Novotný T. The long QT syndrome. Cor Vasa. 2007;49(11):416-425. doi: 10.33678/cor.2007.144.
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