Cor Vasa 2013, 55(4):e324-e329 | DOI: 10.1016/j.crvasa.2013.06.010

Metabolic profile of patients after heart transplantation

Lenka Špinarová^a,b,*, Peter Lidinský^b, Petr Hude^a,b, Jan Krejčí^a,b, Hana Poloczková^a,b, Július Godava^a,b, Jiří Vítovec^a,b

^a I. interní kardioangiologická klinika, Fakultní nemocnice u sv. Anny v Brně, International Clinical Research Center, Brno, Česká republika

^b I. interní kardioangiologická klinika, Lékařská fakulta Masarykovy univerzity, Brno, Česká republika

Orthotopic heart transplantation improves life expectancy and quality of life in patients with severe heart failure. After transplantation, metabolic complications are frequent. They are caused particularly by immunosuppressive therapy. In our cohort of 315 patients, 52% had diabetes mellitus together with hyperlipoproteinemia, hyperlipoproteinemia without diabetes had 41% of patients, diabetes mellitus without hyperlipoproteinemia 3% of patients and none of these disorders only 4% of patients. Therapeutic options with respect to interactions with immunosuppressive therapy are discussed in this article.

Keywords: Diabetes mellitus; Heart transplantation; Hyperlipoproteinemia

Received: December 13, 2012; Revised: June 27, 2013; Accepted: June 27, 2013; Published: August 1, 2013  Show citation