Cor Vasa 2011, 53(8-9):433-438 | DOI: 10.33678/cor.2011.110

Hypertensive emergencies and its management

Tomáš Janota
Centrum pro výzkum, diagnostiku a léčbu arteriální hypertenze, III. interní klinika, Všeobecná fakultní nemocnice a 1. lékařská fakulta Univerzity Karlovy, Praha, Česká republika

Studies of arterial hypertension are engaged especially in a long-term consequences of high blood pressure. Situations when high blood pressure is immediately life-threatening are relatively rare. That's why a proper management of these emergencies is quite difficult. Situations when a substantial sudden increase in blood pressure causes an acute damage of target organs, especially organs of a cardiovascular system, were traditionally called hypertensive crises. Hypertensive crises comprise serious emergencies and not so danger urgencies. The hypertensive emergencies are defined by manifestation of function impairment or even structure damage. However, other situations without apparent manifestation of organ impairment are also involved. Hypertensive urgencies are characterized especially by acute complaints due to high blood pressure. Malignant hypertension and accelerated hypertension with organ damage are also referred to as an urgent hypertensive situation. The latest European and American guidelines for the management of arterial hypertension thus specify just the term of hypertensive emergencies. Treatment of emergent situations is conducted under a permanent monitoring in an intensive care unit. Parenteral nitrates, urapidil, diuretics, angiotensin-converting enzyme inhibitors, calcium channel blockers, beta blockers, alfa blockers, fenoldopam and clonidine are used with respect to organ damage and accompanying diseases. Rate of blood pressure reduction and target values depend on the type of organ damages. An escalation of oral medication is used in the treatment of urgent situations. Treatment in an intensive care unit is usually not necessary. Parenteral medication is indicated only in case of failure of this approach or in any other special circumstances.

Keywords: Hypertensive crisis; Emergent hypertensive situation; Urgent hypertensive situation; Treatment

Published: August 1, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Janota T. Hypertensive emergencies and its management. Cor Vasa. 2011;53(8-9):433-438. doi: 10.33678/cor.2011.110.
Download citation

References

  1. Widimský J jr., Cífková R, Špinar J, et al. Doporučení diagnostických a léčebných postupů u arteriální hypertenze - verze 2007. Doporučení České společnosti pro hypertenzi. Cor Vasa 2008;50:K3-16.
  2. Hypertensive emergency and urgency. Herz 2004;29:354. Go to original source...
  3. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension and of the European Society of Cardiology. Guidelines Committee. 2007 guidelines for the management of arterial hypertension. J Hypertens 2007;25:1105-1187. Go to original source...
  4. Bender SR, Fong MW, Heitz S, Bisognano JD. Characteristics and management of patients presenting to the emergency department with hypertensive urgency. J Clin Hypertens 2006;8:12-18. Go to original source...
  5. Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee: Seventh report of the Joint National Committee on prevention, detection, evaluation, and the treatment of high blood pressure. Hypertension 2003;42:1206-1252. Go to original source... Go to PubMed...
  6. Gardner CJ, Lee K. Hypoperfusion syndrome: Insight into the pathophysiology and treatment of hypertensive encephalopathy. CNS Spectr 2007;12:35-42. Go to original source... Go to PubMed...
  7. Slama M, Modeliar SS. Hypertension in the intensive care unit. Curr Opin Cardiol 2006;21:279-287. Go to original source... Go to PubMed...
  8. Zampaglione B, Pascale C, Marchisio M, Cavallo-Perin P. Hypertensive urgencies and emergencies: Prevalence and clinical presentation. Hypertension 1996;27:144-147. Go to original source...
  9. Thygesen K, Albert JS, White HD on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction. Universal definition of myocardial infarction. Circulation 2007;116:2634-2653. Go to original source... Go to PubMed...
  10. Phung OJ, Baker WL, White CM, et al. Clevidipine: An intravenous dihydropyridine calcium-channel blocker for the treatment of acute hypertension. Formulary 2009;44:102-107.
  11. Fenves AZ, Ram CV. Drug treatment of hypertensive urgencies and emergencies. Semin Nephrol 25:2005;272-280. Go to original source... Go to PubMed...
  12. Elliott WJ. Clinical features in the management of selected hypertensive emergencies. Prog Cardiovasc Dis 2006;48:316-325. Go to original source... Go to PubMed...
  13. Devlin JW, Seta ML, Kanji S, Somerville AL. Fenoldopam versus nitroprusside for the treatment of hypertensive emergency. Ann Pharmacother 2004;38:755-759. Go to original source... Go to PubMed...
  14. Rehman SU, Basile JH, Vidt DG. Hypertensive emergencies and urgencies. In: Black HR, Elliott WJ (eds). Hypertension - a companion to Braunwald's heart disease. Philadelphia: Elsevier Saunders 2007;517-524. Go to original source...
  15. Perez MI, Musini VM. Pharmacological interventions for hypertensive emergencies: a Cochrane systematic review. J Hum Hypertens 2008;22:596-607. Go to original source... Go to PubMed...
  16. Varon J. Diagnosis and management of labile blood pressure during acute cerebrovascular accidents and other hypertensive crises. Am J Emerg Med 2007;25:949-995. Go to original source... Go to PubMed...
  17. Cobanian AV, Bakfis BL, Blafl HR, et al. The Seventh Report of the John National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The JNC 7 Report. JAMA 2003;289:2560-2572. Go to original source...




Cor et Vasa

You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.