Centrum pro výzkum, diagnostiku a léčbu arteriální hypertenze ve Všeobecné fakultní nemocnici v Praze

Jiří Widimský jr.

Cor Vasa 2011, 53(8-9):415-417  

Midterm results of mitral valve repair done on patients with ischemic mitral regurgitation and nonischemic mitral regurgitation

Štefan Lukačín, František Sabol, Ingrid Schusterová, Jana Jevčáková, Helena Vargová, Marián Martinček, Ján Luczy, Martin Beňa, Martin Studenčan, Michal Hulman

Cor Vasa 2011, 53(8-9):470-480 | DOI: 10.33678/cor.2011.117  

Objective: First, to compare early and midterm results of mitral valve repair in patients with ischemic mitral regurgitation (IMR) and nonischemic mitral regurgitation (NIMR). Second, to compare the incidence and effect of comorbidities on early and midterm mortality rates.Methods: A total of 82 patients undergoing mitral valve repair was divided into two groups based on mitral regurgitation etiology. The IMR group included 51 (62.2%) patients and the NIMR group included 31 (37.8%) patients. Diabetes mellitus (DM) was present in 21 cases (41.2% - IMR group) and 4 cases (12.9% - NIMR group); chronic renal insufficiency (CRI) was present in 11 cases...

Non-cardiac causes of cardiac troponin I elevation in the České Budějovice Hospital

Michal Šnorek, Miroslav Verner, František Toušek, Ladislav Pešl

Cor Vasa 2011, 53(8-9):481-485 | DOI: 10.33678/cor.2011.118  

Introduction: Cardiac troponin assessment is an integral part of the evaluation of acute coronary syndromes. These markers of cardiac necrosis can be positive even in the presence of fixed coronary atherosclerotic lesion or in patients with normal findings on the coronary arteries. Many pathological cardiac and non-cardiac conditions may be responsible. Erroneous interpretation of laboratory findings can result in non-indicated intervention on coronary arteries and in harming the patient.Aim: To analyze the causes of cardiac troponin I elevation in the České Budějovice Hospital outside the departments of cardiology and cardiac surgery, to define...

Two years of cooperation between Regional Cardiology Centre and the Centre for Pulmonary Hypertension: results

Daniel Foldyna, Pavel Jansa, Tomáš Snížek, Zdeněk Klimsa

Cor Vasa 2011, 53(8-9):486-489 | DOI: 10.33678/cor.2011.119  

Introduction: Pulmonary hypertension (PH) is a syndrome characterized by increased mean pulmonary artery pressure. It occurs as a part of many different heart and lung conditions but also as a consequence of primary disorder of pulmonary vessels. The prognosis of chronic PH is extraordinarily poor and, without timely treatment, the illness rapidly progresses to right-sided heart failure and death. We present a series of patients with PH resulting from two years of cooperation between our Regional Cardiology Centre and the Centre for Pulmonary Hypertension at the General Faculty Hospital, Prague. This series documents in part the epidemiologic situation...

Large artery properties in arterial hypertension

Ján Rosa, Jiří Widimský jr.

Cor Vasa 2011, 53(8-9):418-422 | DOI: 10.33678/cor.2011.107  

Large artery properties, specifically pulse wave velocity, are important predictors of cardiovascular morbidity and mortality in patients with hypertension, diabetes, end-stage renal disease and in general population as well. Non-invasive arterial stiffness assessment has already been implemented to current European and Czech guidelines for the management of arterial hypertension. The aim of this review is to summarize current knowledge of arterial stiffness, its importance and assessment possibilities.

Management of resistant hypertension

Robert Holaj

Cor Vasa 2011, 53(8-9):423-428 | DOI: 10.33678/cor.2011.108  

Antihypertensive drugs which are effective to decrease blood pressure below values of 140/90 mmHg in all patients with arterial hypertension are still unknown. This review article summarizes some proved diagnostic and therapeutic procedures used in care for patients with resistant hypertension. Combined antihypertensive treatment including aldosterone receptor blocker spironolactone seems to be promising therapeutic approach. At first, non-compliance and secondary hypertension must be excluded. In case of failure of all pharmacotherapy, non-pharmaceutical approaches, such as implantable devices or renal sympathetic denervation, should be considered.

How to assess non-compliance with the pharmacotherapy in severe resistant hypertension?

Branislav Štrauch, Lukáš Chytil, Ivana Kurcová, Ondřej Petrák, Tomáš Zelinka, Ján Rosa, Zuzana Šomlóová, Robert Holaj, Jiří Widimský

Cor Vasa 2011, 53(8-9):429-432 | DOI: 10.33678/cor.2011.109  

Resistant arterial hypertension is defined by impossibility to normalize blood pressure to normal limits (140/90 mmHg) using at least combination of three antihypertensive drugs including a thiazide diuretic. Exclusion of potentially reversible secondary hypertension is needed in patients with resistant hypertension. Partial or total non-compliance of patients with regularly intake antihypertensive drugs is, besides white coat phenomenon, a frequent form of pseudoresistance to the treatment. There are many factors which contribute to the level of adherence, including the characteristics of the patients, prescribed medication and rarely prescribing...

Hypertensive emergencies and its management

Tomáš Janota

Cor Vasa 2011, 53(8-9):433-438 | DOI: 10.33678/cor.2011.110  

Studies of arterial hypertension are engaged especially in a long-term consequences of high blood pressure. Situations when high blood pressure is immediately life-threatening are relatively rare. That's why a proper management of these emergencies is quite difficult. Situations when a substantial sudden increase in blood pressure causes an acute damage of target organs, especially organs of a cardiovascular system, were traditionally called hypertensive crises. Hypertensive crises comprise serious emergencies and not so danger urgencies. The hypertensive emergencies are defined by manifestation of function impairment or even structure damage. However,...

Secondary forms of hypertension, classification and common causes

Zuzana Šomlóová

Cor Vasa 2011, 53(8-9):439-443 | DOI: 10.33678/cor.2011.111  

Secondary hypertension occurs in 5-10% of patients with arterial hypertension. The most common causes are endocrine - particularly primary aldosteronism, renal (renal parenchymal and renovascular) hypertension, sleep apnea syndrome and hypertension in pregnancy. Patients with secondary hypertension often have very high blood pressure. With regard to the possibility of permanent cure / improved control of hypertension, it is useful for patients with suspected secondary form of hypertension to be examined in a specialized centre.

Primary hyperaldosteronism - the common and curable form of endocrine hypertension

Ondřej Petrák

Cor Vasa 2011, 53(8-9):444-448 | DOI: 10.33678/cor.2011.112  

Primary aldosteronism is one of the most common forms of endocrine hypertension which is caused by autonomous aldosterone overproduction. Aldosterone producing adenoma (Conn's syndrome) and bilateral adrenal hyperplasia (idiopathic aldosteronism) are the most frequent subtypes of primary aldosteronism. The highest prevalence of primary aldosteronism can be awaited in patients with moderate to severe arterial hypertension. Early recognition of the disease is important, as this condition may predispose to the increased mortality from cardiovascular disease, and is often reversible with target therapy. It is necessary to consider this diagnose and in...

Is target organ damage more frequent in primary aldosteronism than in essential hypertension?

Tomáš Indra, Robert Holaj

Cor Vasa 2011, 53(8-9):449-453 | DOI: 10.33678/cor.2011.113  

Primary aldosteronism represents one of the common causes of secondary hypertension. Contrary to former assumptions, recent studies proved not only much greater prevalence of the disease among hypertensive population, but also increased risk of cardiovascular and renal damage in comparison with essential hypertension. However, growing evidence constantly suggests, that the risk of cardiovascular and renal complications in primary aldosteronism could be significantly decreased by specific treatment, either surgical or medical. The possibility and good effectivity of this treatment shows the importance of early and correct diagnostics of primary aldosteronism...

Pheochromocytoma - tumor interesting also for cardiologists

Tomáš Zelinka, Hana Turková, Zdeněk Musil, MUDr. Jiří Widimský jr.

Cor Vasa 2011, 53(8-9):454-460 | DOI: 10.33678/cor.2011.114  

Pheochromocytomas and functional paragangliomas are catecholamine-producing tumors which present typical paroxysmal symptoms (headache, palpitations, sweating and hypertension). Biochemical testing for pheochromocytoma is performed by using measurement of metanephrines in either plasma or urine not only in subjects with clinical suspicion of pheochromocytoma but also in subjects with incidentally discovered adrenal mass or in subjects with genetic predisposition for pheochromocytoma and paraganglioma. To localize pheochromocytoma, computed tomography (less frequently magnetic resonance imaging) and functional imaging with [123I]-metaiodobenzylguanidine...

Arterial hypertension in pregnancy: Experience from outpatient clinic for cardiovascular diseases in pregnancy

Jiří Král

Cor Vasa 2011, 53(8-9):461-465 | DOI: 10.33678/cor.2011.115  

Hypertensive disorders in pregnancy consist of a spectrum of conditions, including preexisting hypertension, preeclampsia/eclampsia, preeclampsia superimposed on preexisting hypertension and gestational hypertension. Arterial hypertension in pregnancy is responsible for substantial maternal and fetal morbidity and mortality. The aim of our study was to determine type, prevalence and outcome of arterial hypertension in the cohort of pregnant women controled at a specialized outpatient clinic for cardiovascular diseases in pregnancy. This was a retrospective study of pregnant women examined from January 2006 to December 2009. Fifty-two women (13%) with...

Vascular access for hemodialysis: from renal hypertension to hemodynamics

Jaroslav Kudlička, Jan Malík

Cor Vasa 2011, 53(8-9):466-469 | DOI: 10.33678/cor.2011.116  

The creation of the dialysis vascular access has local and systemic hemodynamic effects. Decrease in the local vascular resistance leads to the acceleration of blood flow, which increases vascular wall shear stress. This ultimately leads to increased production of nitric oxide, dilatation of the feeding artery and increase of blood flow to the limb. High blood flow can cause decompensation of chronic congestive heart failure, less often hyperkinetic heart failure. The most common local complication is ischemia of the limb with the access. The lifespan of native fistulas and accesses with PTFE grafts is limited by the development of stenosis, which...

Unusual body in the pericardium

Tomáš Lazarák, Libor Hemžský, Petr Vojtíšek, Blanka Lacmanová, Vladimír Rozsíval, Ivo Skalský, Tomáš Marek

Cor Vasa 2011, 53(8-9):490-492 | DOI: 10.33678/cor.2011.120  

Chronic expansive intrapericardial hematoma is rare. Sporadic cases following cardiac surgeries, chest traumas, pericardial traumas and percutaneous coronary interventions (PCI) are described in the literature. We present a case report of a 64-year-old man with expansive pericardial hematoma and clinical presentation suggestive of constrictive pericarditis. Three years prior to the diagnosis of chronic pericardial hematoma, the patient had underwent aortocoronary bypass surgery, followed by repeated PCIs. The hematoma was removed surgically. One year after its extirpation, the hematoma recurred and reoperation was necessary. The patient has been free...

Cardiogenic shock as a cause of death in a patient with Churg-Strauss syndrome

Marcel Heczko, Zuzana Gattnarová

Cor Vasa 2011, 53(8-9):493-495 | DOI: 10.33678/cor.2011.121  

Churg-Strauss syndrome, also known as allergic granulomatosis, is a rare systemic disorder characterized by the following triad: bronchial asthma, hypereosinophilia with extravascular eosinophilic granulomas and vasculitis of small- and middle-sized vessels, leading to their necrosis. The vasculitis predominantly affects pulmonary, skin and peripheral nerve vessels but also heart, gastrointestinal tract, kidney or central nervous system. Corticosteroids are the cornerstone of therapy. If untreated, the condition is fatal. Early institution of therapy improves the prognosis considerably.

A case of recurrent of tako-tsubo cardiomyopathy

Jiří Fismol, Igor Nykl, Martin Pleva, Kamil Zeman, Martin Kolek, Marian Branny

Cor Vasa 2011, 53(8-9):496-500 | DOI: 10.33678/cor.2011.122  

Tako-tsubo cardiomyopathy (also called stress or apical balooning cardiomyopathy) is the disease known in cardiology only about twenty years, and as for etiopathogenesis it is quite mysterious. It looks like acute coronary syndrome and this diagnosis is the reason for admitting to cardiocentres. It accounts for around 1% cases among patients with acute coronary syndrome and thus it is thought to be the rarely occurring disease. Recurrences of this illness were described only sporadically. We introduce the case of a woman with recurrence of tako-tsubo cardiomyopathy despite the long-lasting treatment with beta blocker.

Sekundární infarkt myokardu při kontuzi RIA u pacienta po resuscitaci s pomocí systému LUCAS

Vladimír Tuka, Stanislav Šimek, Miroslav Kůdela

Cor Vasa 2011, 53(8-9):501-503 | DOI: 10.33678/cor.2011.123  

Šíření renálního karcinomu dolní dutou žilou do pravostranných srdečních oddílů

Ludmila Jarolímová

Cor Vasa 2011, 53(8-9):503-504 | DOI: 10.33678/cor.2011.124  

European Heart Failure 2011

MUDr. Filip Málek, Ph.D.

Cor Vasa 2011, 53(8-9):509-510 | DOI: 10.33678/cor.2011.127  

Zápis ze schůze výboru ČKS konané dne 31. 5. 2011 v Praze

P. Widimský, I. Pavézková

Cor Vasa 2011, 53(8-9):511-512  

Psát, či nepsat?

Dr. Med. Pavel Jerie

Cor Vasa 2011, 53(8-9):506  

Výbor České kardiologické společnosti, o.s., vyhlašuje výběrové řízení na místo šéfredaktora časopisu

Cor Vasa 2011, 53(8-9):414  

Patnáct let od vzniku Kardiocentra a deset let od vzniku Kardiologické kliniky 3. lékařské fakulty UK a Fakultní nemocnice Královské Vinohrady

Cor Vasa 2011, 53(8-9):507-508