Cor Vasa 2009, 51(5):360-364 | DOI: 10.33678/cor.2009.093

Use of trimetazidine in the treatment of cardiac ischemia

Jiří Krupička
Kardiochirurgické oddělení, Nemocnice Na Homolce, Praha, Česká republika

Trimetazidine improves the metabolism of the ischemic myocardium at the cellular level. In patients with stable angina, it reduces the frequency of anginal attacks and nitrate consumption while increasing exercise tolerance. Because of trimetazidine's additive action, it can be combined with advantage with other antianginal agents. As the agent has no effects on hemodynamic parameters, undesirable effects are negligible. Regarding other indications, no decisions can be made until data from large trials have become available.

Keywords: Trimetazidine; Anti-ischemic action; Angina; Heart failure

Published: May 1, 2009  Show citation

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Krupička J. Use of trimetazidine in the treatment of cardiac ischemia. Cor Vasa. 2009;51(5):360-364. doi: 10.33678/cor.2009.093.
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