Cor et Vasa, 2009 (vol. 51), issue 6

Editorial

Význam C-reaktivního proteinu v prevenci kardiovaskulárních nemocí

Hana Rosolová

Cor Vasa 2009, 51(6):389-391

Original research articles

Left main coronary artery stenosis and its clinical picture

Jan Večeřa, Petr Vojtíšek, Ivo Varvařovský, Jan Matějka, Jiří Kvasnička

Cor Vasa 2009, 51(6):392-396 | DOI: 10.33678/cor.2009.102

Aim: The main objective of our study was to evaluate the clinical picture of patients with left main stenosis and their prognosis in our everyday practice.Material and methods: Ours was a retrospective observational study, with information derived from the medical records of patients having coronary angiography in Pardubice Regional Hospital in 2005. All patients had the left main coronary artery (LMCA) diameter determined using qualitative comparative analysis (QCA). Actual analysis was performed in patients with LMCA stenosis greater than 70% of the artery diameter. Data were obtained from clinical medical records (discharge reports, transfer...

The incidence of risk factors for coronary heart disease in children

Bohuslav Procházka, František Stožický

Cor Vasa 2009, 51(6):397-403 | DOI: 10.33678/cor.2009.103

Aim: The aim of our survey was to determine the current incidence of risk factors of coronary heart disease (CHD) and some related data for children in the Czech Republic, and to compare these data with figures reported by previous studies.Methods: This was a questionnaire-based prospective study organized by the Czech Society of General Practitioners for Children and Adolescents. Data were obtained during preventive checkups of children aged five and 13 years (when some questions related to CHD prevention in children are included according to the healthcare system rules and regulations) and, again, when 17 years old. Evaluated parameters included...

Sex differences in the perioperative and postoperative courses of treatment in adult patients undergoing stenotic aortic valve replacement

Josef Bešík, Jan Pirk, Ivan Netuka, Ondrej Szarszoi, Jiří Malý, Bohuslav Ošťádal

Cor Vasa 2009, 51(6):404-409 | DOI: 10.33678/cor.2009.104

Aim: To determine whether a higher resistance of the female hypertrophied myocardium to ischemic-reperfusion injury can be seen also in clinical medicine.Methods: We performed a retrospective analysis of perioperative and postoperative courses of treatment in hormonally active adult patients undergoing surgery for aortic replacement in our center from 1 January 1995 through 30 June 2004. All patients had aortic valve replacement from midline sternotomy. We were looking for any sex differences.Results: There was no intraoperative or in-hospital death. We did not find any sex differences in the length of hospital stay or the need for inotropic...

Review articles

The Fontan circulation: evolution of a concept

Zdenek Slavik

Cor Vasa 2009, 51(6):410-414 | DOI: 10.33678/cor.2009.105

The Fontan circulation is a specific haemodynamic concept developed and modified over the past 50 years to treat paediatric patients with complex congenital heart defects. The common denominator for these defects is usually a single dominant ventricle supporting both systemic and pulmonary circulation together with cyanosis since birth. Two main palliative cardiac surgical procedures (bidirectional superior cavopulmonary and total cavopulmonary anastomosis) are currently used to establish the Fontan circulation. Refinement of surgical techniques and improved understanding of perioperative and postoperative complications led to improvement in the survival...

The fate of patients surviving at 10 years after heart transplantation with a focus on the incidence of malignant disease

Lenka Špinarová, Petr Hude, Jan Krejčí, Hana Poloczková, Eva Ozábalová, Helena Bedáňová, Petr Němec, Jiří Ondrášek, Jan Černý, Jiří Vítovec

Cor Vasa 2009, 51(6):415-418 | DOI: 10.33678/cor.2009.106

This is a review of 10-year survival of heart transplant recipients at Brno-based centers (Department of Medicine/Cardiology/Angiology I and Center of Cardiovascular and Transplant Surgery) with a focus on the incidence of malignant disease. A total of 95 patients had heart transplantation in the 1993-1997 period. Of this number, 16 died early within six months.The analysis of 10-year survival included 79 patients. The 10-year survival rates of patients treated in 1993-1997 were 67%, 62%, 53%, 54%, and 74%, respectively. Causes of death were malignant disease in four cases (among these, three lymphomas), graft vasculopathy in five, sepsis in two,...

Modulating the levels of circulating BNP by therapeutic approaches for heart failure

Ivan Málek, Markéta Hegarová

Cor Vasa 2009, 51(6):419-424 | DOI: 10.33678/cor.2009.107

Medical therapy is one of the mainstays of treatment of heart failure. Agents that have been shown to be the most effective in this respect are those affecting major neurohormonal systems, i.e., angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), aldosterone antagonists, and beta-blockers.Although treatment of heart failure is governed by generally established rules derived from the outcomes of large trials, it should still be individualized and should be adjusted during the course of the disease depending on the current status. Another major consideration is the correct indication and timing of non-pharmacological...

Reviews

Antonín Mandovec: Kardiovaskulární choroby u žen

Cor Vasa 2009, 51(6):445-446

Images in cardiology

Magnetická rezonance stavu po infarktu myokardu u sedmiletého dítěte s reimplantací anomálního odstupu levé koronární tepny z plicnice

Theodor Adla, Lukáš Mikšík, Helena Bartáková, Viktor Tomek, Roman Gebauer, Miloslav Roček

Cor Vasa 2009, 51(6):427-428 | DOI: 10.33678/cor.2009.109

Reports

Zprávy ze XVII. výročního sjezdu České kardiologické společnosti, Brno, 10.-13. května 2009

Cor Vasa 2009, 51(6):432-440 | DOI: 10.33678/cor.2009.111

Nová dimenze kontroly krevního tlaku a kardiovaskulární prevence - symposium firmy Servier na XVII. výročním sjezdu ČKS

Cor Vasa 2009, 51(6):441-443 | DOI: 10.33678/cor.2009.112

Discussion

Treatment of depression and anxiety disorder after stroke or TIA

Milan Vrána, Radkin Honzák

Cor Vasa 2009, 51(6):425-426 | DOI: 10.33678/cor.2009.108

A proportion of patients after a stroke and transitory ischemic attack (TIA) experiences depression or anxiety. The aim of our study was to test treatment of depression/anxiety with the antidepressant paroxetine in these patients. We retrospectively evaluated outcomes in two subgroups of patients taken out from the basic series of the PrevenPar project. One subgroup included patients after a previous stroke, the other one embraced patients who had had TIA.One-year treatment with the antidepressant paroxetine at an average dose of 20 mg completely suppressed the symptoms of moderate to severe depression/anxiety. Subsets of patients free of symptoms...