Problémy s novými a novějšími hypolipidemiky

Jiří Widimský

Cor Vasa 2008, 50(6):232-234  

Časopisy evropských národních kardiologických společností

Cor Vasa 2008, 50(6):235-240  

Our initial experience with genetic testing of patients with hypertrophic cardiomyopathy: mutations of troponin T and troponin I genes

Karol Čurila, Martin Pěnička, Marek Minárik, Hana Línková, Lucie Benešová, Pavel Gregor

Cor Vasa 2008, 50(6):242-245 | DOI: 10.33678/cor.2008.080  

Introduction:Hypertrophic cardiomyopathy (HCM) is an autosomal hereditary dominant disorder caused by mutations in genes encoding cardiac sarcomeric proteins. Troponin T and troponin I make an important part of the heart muscle sarcomere and mutations in their genes are responsible for developing HCM. The frequency of these 2 genes is reported to be about 3-15%. Method:We studied the prevalence of mutations in troponin T and troponin I genes in 40 individuals with HCM on follow-up in the Heart Center of a Prague-based hospital. DNA samples were genetically tested using direct bidirectional sequencing of PCR products. Genetic...

Thrombolytic therapy in acute pulmonary embolism

Vladimír Dytrych, Jan Bělohlávek, Tomáš Kovárník, Pavel Jansa, Aleš Linhart, Michael Aschermann

Cor Vasa 2008, 50(6):246-253 | DOI: 10.33678/cor.2008.081  

Acute pulmonary embolism is a relatively frequent condition with a variable clinical course. The authors discuss in detail the current indications for thrombolytic therapy in patients with this condition and the relevance of risk stratification, which should play the pivotal role in future therapeutic decision-making.

Papillary muscle rupture with hemodynamically significant mitral regurgitation as a result of atypical acute myocardial infarction in a 31-year-old man

Jiří Samlík, Radim Brát, Tomáš Daněk, Jan Gloger

Cor Vasa 2008, 50(6):254-257 | DOI: 10.33678/cor.2008.082  

In our paper, we report the case of an atypical acute myocardial infarction in a young man with a rare complication-papillary muscle rupture with hemodynamically significant mitral regurgitation-requiring surgery (coronary artery bypass grafting and mitral valve repair). Soon after hospitalization, the patient developed bilateral bronchopneumonia associated with the adult respiratory distress syndrome requiring mechanical ventilation.

Nové možnosti léčby výdutí oblouku aorty hybridním přístupem

Jan Vojáček, Miroslav Lojík, Tomáš Daněk, Jan Dominik, Jan Harrer

Cor Vasa 2008, 50(6):241 | DOI: 10.33678/cor.2008.079  

Odborná konference ošetřovatelství v kardiologii, 5. dubna 2008, Praha

Cor Vasa 2008, 50(6):K95  

Zápis ze schůze výboru ČKS, konané dne 22. dubna 2008 v Praze

Cor Vasa 2008, 50(6):K96  

Management of chronic heart failure

Jiří Vítovec, Jindřich Špinar

Cor Vasa 2008, 50(6):259-267 | DOI: 10.33678/cor.2008.083  

The approach to the patient with cardiac insufficiency has changed markedly over the past decade. Current management is focused not only on modulating symptoms of dyspnea and fatigue but, primarily, on modulating the incidence and progression of heart failure and reducing mortality. Most therapeutic strategies today are based on the results of large randomized studies, which have demonstrated that the therapeutic approach in question is beneficial for the patient, either by extending their lives and/or improving their quality of life. In addition to the impressive advances made in drug therapy, the prognosis of patients has been largely affected by...

Zamyšlení nad časopisem České kardiologické společnosti

Cor Vasa 2008, 50(6):K92  

Profesor MUDr. Vladimír Staněk, CSc., FESC, 75 let

Cor Vasa 2008, 50(6):K93  

Profesor MUDr. Jan Pirk, DrSc., šedesátníkem

Cor Vasa 2008, 50(6):K94