Cor et Vasa, 2002 (vol. 43), issue 5
Original research articles
Clinical utility of catheter ablation for tachycardias from the sinus node region
Martin Fiala, Petr Heinc, Jan Lukl
Cor Vasa 2002, 43(5):213-218
Introduction:Tachycardias from the sinus node region represent a spectrum of arrhythmias with an unknown mechanism that may produce serious disabling symptoms. The clinical and electrophysiological characteristics, and results of catheter ablation of these tachycardias are reported. Patients and methods:Seven consecutive patients (6 females) aged 39.7 ± 13.9 (20-64) years underwent 10 ablation procedures for symptomatic, drug-resistant tachycardia from the sinus node region. Selective ablation of the tachycardia was the primary end-point of the procedure. Results:Different clinical and electrophysiological...
Primary coronary angioplasty as a routine treatment of acute myocardial infarction with ST elevation
Michael Želízko, Bronislav Janek, Jiří Kettner, Marek Hrnčárek, Vladimír Pořízka, Vladimír Karmazín, Jan Šochman
Cor Vasa 2002, 43(5):220-226
Introduction:Randomized studies in selected groups report an in-hospital mortality of 2-4% in patients with acute myocardial infarction (AMI) treated by primary transluminal coronary angioplasty (primary PTCA). The aim of our study was to determine the value of this method as a routine reperfusion strategy in the treatment of AMI with ST elevation in all admitted patients without any selection whatsoever. Methods:The group included 245 AMI patients (76% of men and 24% of women with a mean age of 60.4 years) treated by primary PTCA. Anterior, posterior, and lateral wall myocardial infarction was diagnosed in 45%, 40%, and 12%...
Managing internal carotid stenoses by stent implantation
Václav Procházka, Vladimír Čížek, Dušan Kučera, Karel Dvořák, Jan Rajner
Cor Vasa 2002, 43(5):227-232
Aim:To review the indications and outcome of percutaneous transluminal angioplasty (PTA) with stent implantation in patients with significant internal carotid artery stenoses. Method:Patients with the diagnosis of significant internal carotid artery stenoses established by ultrasound had additional assessments by brain panangiography, as well as neurological and other paraclinical examinations performed. Indicated patients had subsequent percutaneous transluminal angioplasty using a self-expandable stent. Starting in mid-2000, the procedure was combined with the use of a protective filter. All patients were monitored by a...
Cardiac injury in primary hyperaldosteronism and essential hypertension of identical severity
Tomáš Janota, Jiří Widimský jr, Tomáš Zelinka, Jaromír Hradec, Jiří Král, Pavel Horák, Eva Kábrtová, Tomáš Haas
Cor Vasa 2002, 43(5):234-242
Aim:To evaluate the clinical relevance of hormonal non-hemodynamic factors for the development of cardiac injury in primary hyperaldosteronism (PHA). To compare the reversibility of cardiac injury after adrenalectomy and spironolactone therapy. Methods:Twenty-three patients with aldosterone-producing adenoma (APA), 23 patients with idiopathic hyperaldosteronism (IHA), and 23 patients with essential hypertension (EH) of identical severity were examined by echocardiography. PHA patients were re-examined 2.5 years after adrenalectomy or spironolactone therapy. The subgroups did not differ significantly in terms of age, male/female...
Infected pacemaker extraction and alcoholic interventricular septal ablation in a female patient with obstructive hypertrophic cardiomyopathy
Petr Neužil, Pavel Formánek, Miloš Táborský
Cor Vasa 2002, 43(5):244-248
The present case report describes a female patient implanted a dual-chamber pacemaker because of left ventricular (LV) outflow tract obstruction in the presence of hypertrophic cardiomyopathy (HCMP). Despite cardiac pacing, the patient was significantly symptomatic, with exertional dyspnoe of NYHA Class II-III, occasional palpitations and exertional-related chest pain.Following pacemaker re-implantation because of battery energy running low, the patient developed bed sore showing signs of infection within the subcutaneous pocket accommodating the device. The patient was admitted to our department for transvenous extraction of both pacing leads....
New mutation in the KCNQ1 gene identified in a Czech patient with the LQT phenotype
Tomáš Novotný, Jitka Kadlecová, Renata Gaillyová, Bořivoj Semrád
Cor Vasa 2002, 43(5):250-252
Background:The long QT syndrome (LQTS) is a monogenic disorder characterized by prolongation of the QT interval on ECG and syncope or sudden death caused by polymorphic ventricular tachycardia (torsade de pointes). To date, six loci and five genes have been related to this syndrome. The most commonly affected are the KCNQ1 (11p15.5) and HERG (7q35-36) genes. Methods and results:KCNQ1 gene analysis (multiplex single strand conformational polymorphism and DNA sequence analysis - ABI Prism 310 sequencer) was performed in 12 families with the clinical diagnosis of LQTS. In two of them, mutations in the KCNQ1 gene were found. In...
Short communication
Acute myocardial infarction at Prague's coronary care units in 1980 and 2000
Jiří Spáčil, Jaromír Hradec
Cor Vasa 2002, 43(5):254-256
In the early 1980s and in the year 2000, we evaluated the incidence and mortality of acute myocardial infarction in Prague. Over the 20-year period, mortality at coronary care units decreased from 13.7% to 9.7%. In-hospital mortality in Prague dropped from 21.7% to 9.6%. In 2000, direct coronary angioplasty was performed in 51% of patients. The interval from the onset of symptoms to hospital admission remained unchanged over the above period and its median is about 5 hours.