Vazodilatační léčba aneb 20 let klinických studií srdečního selhání

Jiří Vítovec

Cor Vasa 2006, 48(11):373-375 | DOI: 10.33678/cor.2006.121  

The risk factor profile of patients undergoing cardiovascular surgery and their relatives

Alena Lorenzová, Hana Pospíšilová, Marek Šetina, Petr Stávek, Věra Lánská, Rudolf Poledne

Cor Vasa 2006, 48(11):379-383 | DOI: 10.33678/cor.2006.123  

Introduction:Pro-inflammatory status measured as elevated levels of high-sensitive CŚreactive protein (hsCRP) has been shown to be a risk factor for atherosclerosis progression, but the mechanisms contributing to its elevation are not clearly elucidated yet. In order to prove our theory that there is a strong genetic background regulating hsCRP concentration, we studied potential genetic and environmental effects in patients undergoing elective coronary revascularization (coronary artery bypass grafting, CABG), their spouses and offspring. Method:All consecutive male patients (n = 200) under 65 years of age admitted to the...

Using free plasma metanephrines in the diagnosis of pheochromocytoma

Jan Václavík, David Stejskal, Bořek Lačňák, Václav Hanák, Marie Lazárová, Libor Jedelský, Lenka Kadalová, Marie Janošová, Zdeněk Fryšák, Petr Vlček

Cor Vasa 2006, 48(11):384-387 | DOI: 10.33678/cor.2006.124  

Introduction:The critical step in diagnosing pheochromocytoma is biochemical evidence of hyperproduction of catecho-lamines or their metabolites. Methods:A cross-sectional multicenter study including 1,234 subjects assessed the diagnostic validity of determining plasma metanephrines in patients screened for resistant or markedly accelerated hypertension, paroxysmal hypertension, "flushes", adrenal incidentaloma or genetic predisposition to pheochromocytoma. Results:Pheochromocytoma was identified and verified by histology in 18 individuals (1.5%), with the diagnosis notconfirmed by long-term follow-up and...

NT-proBNP as a non-invasive marker of acute rejection in heart transplant recipients

Helena Bedáňová, Erik Petrikovits, Josef Nečas, Petr Pavlík, Pavel Studeník, Jiří Ondrášek, Jan Černý, Petr Breinek, Lenka Špinarová

Cor Vasa 2006, 48(11):388-390 | DOI: 10.33678/cor.2006.125  

Aim:The aim of our study was to determine whether NT-proBNP (N-terminal pro brain natriuretic peptide) could be used in clinical practice as a non-invasive marker of rejection after heart transplantation (HTx). Method:The study included 46 patients undergoing HTx, with the first four endomyocardial biopsy (EMB) samples of each assessed, giving a total of 184 samples and their respective NT-proBNP values. Excluded were patients with renal insufficiency, i.e., those with creatinine levels > 150 µmol/l on the day of biopsy. The remaining patients were divided into two groups. Group A comprised 116 biopsy samples (with...

Indications for coronary artery bypass grafting

Petr Widimský, Zbyněk Straka

Cor Vasa 2006, 48(11):392-398 | DOI: 10.33678/cor.2006.126  

This review article summarizes in detail the indications for coronary artery bypass grafting (CABG) based on clinical criteria, coronary angiography finding, left ventricular function, and operative risk estimate using various techniques. Utmost emphasis is placed on operative risk estimate using what is referred to as the EuroSCORE. The long-term outcomes of CABG are also addressed. The authors clearly identify conditions under which it is preferable to perform surgery or to institute conservative therapy. A short comparison of CABG and percutaneous coronary intervention (PCI) is included. The need is underlined for the physician making the indication...

Post-traumatic mediastinal cyst

Milan Hrdlička, Tomáš Brabec, Ladislav Kalas, Jan Černý

Cor Vasa 2006, 48(11):399-401 | DOI: 10.33678/cor.2006.127  

The differential diagnosis of chest pain is one of the most common problems faced by physicians of emergency medicalservice and outpatient departments of internal medicine and neurology.The paper is the case report of a 31-year-old man with a post-traumatic mediastinal cyst diagnosed at the Department of Medicine of the Brno-based Military Hospital and subsequently removed during scheduled on-pump surgery in the Cardiovascular and Transplant Surgery Center. Postoperative complications are also briefly mentioned.

Perikardiální konstrikce v zobrazení magnetickou rezonancí

Theodor Adla

Cor Vasa 2006, 48(11):376 | DOI: 10.33678/cor.2006.122  

Managing diastolic heart failure. Results of PEP-CHF

Jiří Widimský

Cor Vasa 2006, 48(11):403-407  

PEP-CHF (Perindopril in Elderly People with Chronic Heart Failure) was a one-year, randomised, double-blind study comparing the effects of the ACE inhibitor perindopril and placebo on mortality and morbitidy in elderly patients with chronic heart failure secondary to diastolic left ventricular dysfunction. This was the first study of chronic heart failure assessing diastolic left ventricular dysfunction by echocardiography. The study included 850 patients with a mean age of 76 years. It included cases of mild to moderate chronic heart failure, as most patients (74-77%) were classified in NYHA Class II/I, as also reflected by low overall mortality rates....

Katetrizační modifikace chlopenních vad srdce - zastavení po prvních krocích v nové etapě experimentální a klinické kardiologie

Cor Vasa 2006, 48(11):K204  

Světový kardiologický kongres Barcelona 2. 9.-6. 9. 2006

Cor Vasa 2006, 48(11):K207  

Zápis ze schůze výboru ČKS, konané dne 19. září 2006 v Brně

Cor Vasa 2006, 48(11):K209  

Zápis ze schůze výboru pracovní skupiny (PS) Srdeční selhání, 22. 9. 2006

Cor Vasa 2006, 48(11):K211  

Kalendář odborných akcí

Cor Vasa 2006, 48(11):K212