Cor et Vasa, 2002 (vol. 43), issue 3
Original research articles
Angina is a predictor of myocardial viability in low-ejection fraction patients undergoing percutaneous revascularization
Ewa Gaszewska-Żurek, Paweł Buszman, Michał Tendera
Cor Vasa 2002, 43(3):115-121
Introduction:In patients with regional myocardial contractility abnormalities, revascularization procedures should be preceded by their viability status assessment. In the present work, we investigated if angina may be an indicator of myocardial viability. Subjects and methods:In a group of 80 patients with baseline left ventricular ejection fraction (EF) Ł 40% who underwent PTCA, the following echocardiographic parameters were assessed before and after angioplasty: EF, wall motion index (WMI), asynergy area index (AAI) and contractility of revascularized segments. Patients were divided into group A - 29 pts with anginal symptoms...
What is the fate of adults with chronic cyanosis in congenital heart disease?
Jana Popelová, Jan Škovránek, Jan Marek, Petr Tax, Bohumil Hučín, Tomáš Honěk
Cor Vasa 2002, 43(3):122-127
Aim:The study was designed to establish the status and current potential for the treatment of a unique patient population surviving into adulthood with chronic cyanosis in congenital heart disease. Group of patients:We retrospectively evaluated 1,106 adults with congenital heart disease, examined at the Adult Congenital Heart Disease Counseling Center at the Department of Internal Medicine, Motol University Hospital, in the 1993-2001 period. Results:Overall, 77 (7 %) had cyanotic congenital heart disease with a resting O2 saturation below 90%. They were 40 women (52%) and 37 men with a mean age of 37 ±...
Fenofibrate therapy has a beneficial effect on LDL particle size
Petr Stávek, Rudolf Poledne
Cor Vasa 2002, 43(3):129-133
Aim of study:To establish whether micronized fenofibrate therapy in patients with mixed hyperlipoproteinemia in routine outpatient practice has an effect on LDL particle size. Methods:A group of patients included 229 individuals (168 men and 61 women) whose plasma samples (and personal medical history data) had been sent in for analysis from 45 outpatient offices of cardiologists and internists from all over the country. The number of patients indicated for fibrate therapy from each physician's office was 2-10. Of this number, 167 (73%) had had a myocardial infarction. The size of the main LDL fraction particles was determined...
A comparison of ultrasound findings of hemodynamically significant dialysis vascular access stenoses with angiography
Jan Malík, Marcela Slavíková, Jana Mašková, Jaromír Hradec
Cor Vasa 2002, 43(3):154-158
Introduction:Early diagnosis of hemodialysis vascular access stenosis is important for maintaining long-term shunt patency and function. Ultrasound is a non-invasive alternative to angiography in diagnosing stenoses. The aim of the study was to establish the sensitivity and specificity of ultrasound-based diagnosis of hemodynamically significant stenoses compared with digital subtraction angiography (DSA) as the gold standard. Patients and methods:The ultrasound and DSA findings in 49 patients were compared. The vascular bed of the afferent artery and efferent vein was divided into 7 segments with native shunts, and into 6...
Review articles
Neurogenic hypertension-current therapeutic options
Václav Masopust, David Netuka, Vladimír Beneš, František Charvát
Cor Vasa 2002, 43(3):139-142
Neurogenic hypertension is an often discussed topic. The aim of this article is not to explain the concept of neurogenic hypertension, but to show how to handle diagnostic and surgical problems associated with neurogenic hypertension. The current state of preparation for routine surgery for neurogenic hypertension is described. Our experience with surgery in the posterior fossa for functional disorders as well as for oncological and vascular reasons enables us to think about the risks to be faced when establishing surgery for neurogenic hypertension. The pathophysiology of neurogenic hypertension as well as the surgical approach to this disease are...
Aortic dissection-a less frequent cause of ischemic stroke. A case report and a review of the literature
Bohdan Křupka, Alice Hlobilková, Jan Galuszka, Vlastislava Tichá, Roman Herzig, Ivanka Vlachová
Cor Vasa 2002, 43(3):143-146
Ischemic stroke is the third most frequent cause of death in this country. A variety of conditions treated by internists and cardiologists manifest themselves by symptoms related to nervous system impairment. With aortic dissection, this is so in some 20-30% of cases, with ischemic stroke or hypoxic encephalopathy being the most frequent manifestations. The authors report the case of a 46-year-old man with a history of arterial hypertension, transferred to our department with symptoms of acute right-side supratentorial stroke. Subsequent examination (carotid duplex ultrasound, chest x-ray, transthoracic echocardiography and computed tomography with...
Short communication
Tissue factor, tissue factor pathway inhibitor, and soluble P-selectin levels in patients with acute coronary syndromes. A preliminary report
Jan Vojáček, Martin Malý, Vladimír Hraboš, Martin Mates, Petr Hájek, David Horák, Václav Durdil, Michal Semrád, Jan Kvasnička, Petr Salaj
Cor Vasa 2002, 43(3):148-151
Introduction:Tissue factor (TF) is expressed on monocytes entering the atherosclerotic plaque and is present in large amounts in the atherosclerotic plaque. After plaque rupture, it gets in contact with circulating blood and, when bound to activated factor VII (fVIIa), it triggers the coagulation cascade. The natural inactivator of the TF/fVIIa complex is the complex of tissue factor pathway inhibitor (TFPI) with factor Xa (fXa). Besides, TF becomes expressed on the surface of circulating monocytes as a result of their activation. Group of patients:The study was designed to compare the levels of TF, TFPI, soluble P-selectin...