Cor Vasa 2025, 67(Suppl.3):41-46 | DOI: 10.33678/cor.2025.077

Double-vessel disease of acute myocardial infarction in a 27-year-old young female: a case report

Okky Wahyu Firmansyah^{a, b}, Christian Pramudita Budianto^{a, b}, Pandit Bagus Tri Saputra^{a, b}, Faizal Ablansah Anandita^{a, b}

^a Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

^b Department of Cardiology and Vascular Medicine, Faculty of Medicine, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia

Acute myocardial infarction (AMI) is an uncommon occurrence in young people. Furthermore, females suffering from AMI reported much lower rates due to poor symptom recognition, less defined "atypical" chest pain, and some normal angiographic findings. However, recent studies have highlighted an increase in the incidence of AMI in younger patients with single-vessel disease, which is the most prevalent angiographic feature. To date, AMI in young females has received less study, especially in cases of double-vessel disease. The present case study aims to contribute to the existing body of knowledge by offering a detailed analysis of a young female patient who has experienced an AMI and has been diagnosed with double-vessel disease. A 27-year-old Indonesian female was transferred to our hospital with a syncope presentation, preceded by acute chest pain. An electrocardiogram shows ST elevation in anterior leads (V₃-V₆) and inferior leads. From lab examination, the patient has hypertriglyceridemia (262 mg/dL) and abnormal plasma glucose (516 mg/dL), with the possibility of type 2 diabetes mellitus. Coronary angiogram results revealed double-vessel occlusions at the middle right circumflex artery (RCA) at 99% and the proximal-middle left anterior descending coronary artery (LAD) at 70%. Percutaneous coronary intervention (PCI) was conducted at RCA as the most critical occlusion site. Type 2 diabetes was the contributing risk factor for the patient. History taking of family and personal diseases is important to comprehend the cause of AMI occurrence at an early age.

Keywords: Acute myocardial infarction, Double-vessel disease, Female, Diabetes, Obstructive CAD

Received: June 22, 2024; Revised: February 28, 2025; Accepted: July 6, 2025; Prepublished online: June 2, 2012; Published: September 1, 2025  Show citation