Cor Vasa 2018, 60(6):e622-e630 | DOI: 10.1016/j.crvasa.2018.03.004

Cardiac resynchronization therapy in the Czech Republic - Data from the EHRA CRT Survey II multicenter registry

Alan Bulava^a,b,c,*, Přemysl Hájek^a, Josef Kautzner^d, Petr Pařízek^e, Petr Neužil^f, Rostislav Polášek^g, Jan Večeřa^h, Pavel Osmančík^ch, Jan Chovančíkⁱ, Milena Kubíčková^j, David Šipula^k, Kenneth Dickstein^l, Cecilia Linde^m, Camilla Normandⁿ

^a Oddělení kardiologie, Kardiocentrum, Nemocnice České Budějovice, a.s., České Budějovice, Česká republika

^b Lékařská fakulta Univerzity Palackého, Olomouc, Česká republika

^c Zdravotně sociální fakulta Jihočeské univerzity v Českých Budějovicích, České Budějovice, Česká republika

^d Klinika kardiologie, Institut klinické a experimentální medicíny, Praha, Česká republika

^e I. interní kardioangiologická klinika, Fakultní nemocnice Hradec Králové, Hradec Králové, Česká republika

^f Kardiologické oddělení, Nemocnice Na Homolce, Praha, Česká republika

^g Kardiologické oddělení, Krajská nemocnice Liberec, Liberec, Česká republika

^h Kardiologické centrum AGEL, Pardubice, Česká republika

^ch III. interní klinika - kardiologická klinika, Fakultní nemocnice Královské Vinohrady, Praha, Česká republika

ⁱ Kardiologické oddělení, Nemocnice Podlesí, a.s., Třinec, Česká republika

^j Kardiologická klinika, Masarykova nemocnice v Ústí nad Labem, o. z. - Krajská zdravotní, a.s., Ústí nad Labem, Česká republika

^k Kardiovaskulární oddělení, Fakultní nemocnice Ostrava, Ostrava, Česká republika

^l Stavanger University Hospital, Stavanger, Norway a Institute of Internal Medicine, University of Bergen, Bergen, Norsko

^m Heart and Vessels Theme, Karolinska University Hospital a Karolinska Institutet Stockholm, Stockholm, Švédsko

ⁿ Stavanger University Hospital, Stavanger a Institute of Internal Medicine, University of Bergen, Bergen, Norsko

Introduction: Cardiac resynchronization therapy (CRT) has been proven to lower mortality and morbidity in selected patients with chronic congestive heart failure. The first prospective ESC (European Society of Cardiology) registry showed that indications for CRT were broadly extrapolated to groups of patients, who were not adequately represented in published randomized trials. Significant differences were also documented regarding implantation techniques between different regions and countries. The goal of this article is to explore the second international registry EHRA CRT II Survey and compare the data retrieved from this registry to common clinical practice in the Czech Republic.

Methods and results: Two ESC associations, the European Heart Rhythm Association (EHRA) and the Heart Failure Association (HFA) designed a second prospective survey to describe current clinical practice regarding CRT. The registry included data on 11,088 patients from 42 ESC member states (ESCMS). In the Czech Republic, 14 centers agreed to participate and finally, 10 actively enrolling centers contributed data from 931 patients (mean age 69.4 ± 9.9 years, 23% women). Mean procedural and X-ray times were significantly lower in the Czech Republic compared to the overall data. Biventricular cardioverter-defibrillators compared to biventricular pacemakers were implanted more often in the Czech Republic (OR 1.74, 95% CI 1.47-2.05, p < 0.0001). CRT devices were most often implanted by electrophysiologists (OR 6.18, 95% CI 4.56-8.37, p < 0.0001) and patients presented less often with a typical left bundle branch block ECG pattern (OR 0.54, 95% CI 0.47-0.62, p < 0.001), and more often with atrial fibrillation (OR 1.32, 95% CI 1.15-1.51, p < 0.001). Telemedical monitoring was used less in the Czech Republic compared to the rest of the ESCMS (OR 0.41, 95% CI 0.34-0.49, p < 0.0001).

Conclusion: The second CRT registry is a valuable source of information on current clinical practices, indications, and results regarding this invasive heart failure therapy. Comparisons of data derived from the Czech Republic with the other ESCMS data set showed that the Czech Republic is among the top 10 countries with respect to the number of procedures, implantation success, and low complication rates. However, use of telemonitoring systems is rather low compared to the European average. A significant number of patients were indicated for CRT based on indications not covered by the Class I of the current recommendations (i.e., those with the best evidence).

Keywords: Cardiac resynchronization therapy; Quality of care; Health care utilization; Registry; Demography

Received: January 20, 2018; Accepted: March 7, 2018; Published: December 1, 2018  Show citation