Cor Vasa 2017, 59(5):e430-e435

Rapidly progressive heart failure in a patient with restrictive cardiomyopathy secondary to newly diagnosed multiple myeloma

Zuzana Jadvišová^*, Jiří Knot, Zuzana Moťovská

III. interní-kardiologická klinika, Kardiocentrum, 3. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Královské Vinohrady, Praha, Česká republika

Restrictive cardiomyopathy is a rare disease of the myocardium characterized by elevated filling pressures, limited left ventricular filling with usually normal systolic function. The most common cause in our geographic region is AL amyloidosis. This paper describes the case of a patient in whom multiple myeloma was diagnosed in an advanced stage of the disease, with organ damage and progressive heart failure, which was gradually reducing the quality of life and which despite the initiation of intensive treatment led to a patient's death.
This case proves that the disease gets little attention, is diagnosed late, and therefore it is important to remind this diagnosis. Early detection of the etiology of heart failure has a significant impact on the effectivity and success of treatment.

Keywords: AL amyloidosis; Heart failure; Multiple myeloma; Restrictive cardiomyopathy

Received: July 25, 2016; Revised: September 6, 2016; Accepted: September 15, 2016; Published: October 1, 2017  Show citation