Cor Vasa 2016, 58(5):e470-e473 | DOI: 10.1016/j.crvasa.2016.02.005

Chondrosarcoma resection followed by a branched crural revascularization of the right calf: Case report

Róbert Novotnýa,*, Jan Lessenskýb, Jan Hrubýa, Jaroslav Hlubockýa, Petr Mitáša, Jaroslav Lindnera
a II. chirurgická klinika kardiovaskulární chirurgie, Kardiovaskulární centrum, 1. lékařská fakulta Univerzity Karlovy a Všeobecná fakultní nemocnice v Praze, Praha, Česká republika
b Ortopedická klinika, Nemocnice Na Bulovce, Praha, Česká republika

Background: Chondrosarcoma is a malignant bone tumor accounting for 20% of all bone malignancies. We are presenting a case of a lower extremity recurrence of chondrosarcoma that encapsulated the anterior tibial artery and the fibular artery in a 35-year-old Caucasian male patient. The patient underwent a primary resection of a chondrosarcoma of the right lower extremity 3 years ago. The patient underwent regular MRI and CT check-ups of the affected lower extremity. The patient reported a hard palpable mass with intermittent pain attacks and occasional limb swelling on his right calf 3 years from the initial surgery. A CT scan revealed a new tumor arising from the tibial bone in the place of the original tumor resection.
Case presentation: After a CT angiography revealed the tumor's anatomical localization to the surrounding structures, we performed a surgical resection of the entire tumor with a safe margin of soft tissue and encapsulated crural arteries. Extra attention was paid to the preservation of the tibial nerve. The resected crural arteries were replaced with a branched crural reconstruction (popliteal-fibular, anterior tibial bypass). Due to the young age of the patient, the great saphenous vein was the first choice as a graft for the vascular reconstruction. After the tumor resection, the patient was instantly relieved from intermittent pain attack and limb swellings. Based on the preoperative evaluation of the tumor and its surrounding structures, the patient underwent a complete tumor resection with crural arteries reconstruction after which the patient retained full limb functionality. The branched crural arteries reconstruction that replaced the resected crural arteries remains patent up-to-date with no signs of stenosis, when checked by Doppler ultrasonography.

Conclusion: Wide resection is the only adequate surgical treatment of choice and has to be planned carefully.

Keywords: Arterial reconstruction; Branched bypass; Chondrosarcoma; Resection; Tibia

Received: January 31, 2016; Accepted: February 6, 2016; Published: October 1, 2016  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Novotný R, Lessenský J, Hrubý J, Hlubocký J, Mitáš P, Lindner J. Chondrosarcoma resection followed by a branched crural revascularization of the right calf: Case report. Cor Vasa. 2016;58(5):e470-473. doi: 10.1016/j.crvasa.2016.02.005.
Download citation

References

  1. L.R. Leddy, R.E. Holmes, Chondrosarcoma of bone, Cancer Treatment and Research 162 (2014) 117-130. Go to original source... Go to PubMed...
  2. C.D.M. Fletcher, K.K. Unni, F. Mertens (Eds.), World Health Organization, IARC Press, Lyon, France, 2002.
  3. F. Chang, G.Y. Liu, Q. Zhang, et al., Malawer limb salvage surgery for the treatment of scapular chondrosarcoma, World Journal of Surgical Oncology 12 (2014) 196. Go to original source... Go to PubMed...
  4. T.A. Damron, W.G. Ward, A. Stewart, Osteosarcoma, chondrosarcoma, and Ewing's sarcoma: National Cancer Data Base Report, Clinical Orthopaedics and Related Research 459 (2007) 40-47. Go to original source... Go to PubMed...
  5. H. Gelderblom, P.C. Hogendoorn, S.D. Dijkstra, et al., The clinical approach towards chondrosarcoma, Oncologist 13 (2008) 320-329. Go to original source... Go to PubMed...
  6. M.E. Pring, K.L. Weber, K.K. Unni, F.H. Sim, Chondrosarcoma of the pelvis. A review of sixty-four cases, Journal of Bone and Joint Surgery 83-A (2001) 1630-1642. Go to original source...
  7. M.U. Mermerkaya, S. Bekmez, F. Karaaslan, et al., Intralesional curettage and cementation for low-grade chondrosarcoma of long bones: retrospective study and literature review, World Journal of Surgical Oncology 12 (2014) 336. Go to original source... Go to PubMed...
  8. B. Chmielowski, N. Federman, W.D. Tap, Clinical trial end points for assessing efficacy of novel therapies for soft-tissue sarcomas, Expert Review of Anticancer Therapy 12 (2012) 1217-1228. Go to original source... Go to PubMed...
  9. A. Italiano, O. Mir, A. Cioffi, et al., Advanced chondrosarcomas: role of chemotherapy and survival, Annals of Oncology 24 (2013) 2916-2922. (Epub ahead of print) Go to original source... Go to PubMed...
  10. A.M. van Maldegem, H. Gelderblom, E. Palmerini, et al., Outcome of advanced, unresectable conventional central chondrosarcoma, Cancer 120 (2014) 3159-3164. (Epub ahead of print) Go to original source... Go to PubMed...
  11. N. Greco, T. Schott, X. Mu, et al., ALDH activity correlates with metastatic potential in primary sarcomas of bone, Journal of Cancer Therapy 5 (2014) 331-338. Go to original source... Go to PubMed...
  12. J.C. Chen, S.T. Yang, C.Y. Lin, et al., BMP-7 enhances cell migration and avb3 integrin expression via a c-Src-dependent pathway in human chondrosarcoma cells, PLOS ONE 9 (2014) e112636. Go to original source... Go to PubMed...
  13. M. Tonak, M. Becker, C. Graf, et al., HDAC inhibitor-loaded bone cement for advanced local treatment of osteosarcoma and chondrosarcoma, Anticancer Research 34 (2014) 6459-6466. Go to PubMed...
  14. F.M. Wodajo, J. Bickels, J. Wittig, M. Malawer, Complex reconstruction in the management of extremity sarcomas, Current Opinion in Oncology 15 (2003) 304-312. Go to original source... Go to PubMed...




Cor et Vasa

You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.