Cor Vasa 2015, 57(3):e176-e180 | DOI: 10.1016/j.crvasa.2015.03.007
Clinical impact of left atrial appendage resection versus preservation during surgical ablation of atrial fibrillation
- a Kardiochirurgické oddělení, Nemocnice České Budějovice, a. s., České Budějovice, Česká republika
- b Zdravotně sociální fakulta, Jihočeská univerzita, České Budějovice, Česká republika
Introduction: Resection of left atrial appendage (LAA) during surgical ablation of atrial fibrillation may decrease the incidence of postoperative cerebrovascular events and increase the induction and maintenance of sinus rhythm (SR). This study evaluates the effect of LAA resection after the surgical ablation of atrial fibrillation.
Materials and methods: A retrospective analysis was made of 599 patients who underwent surgical myocardial revascularization and/or valve surgery with concomitant surgical ablation of atrial fibrillation. The LAA was resected in 140 patients and preserved in 459 patients. Postoperative, 1-month and 1-year results were compared between the groups in terms of TIA/CVA, maintenance of sinus rhythm, pacemaker dependence and mortality.
Results: The patients who underwent LAA resection were older, had more frequent persistent AF and underwent more frequently biatrial ablation set. In this group, longer times of extracorporeal circulation and longer cross-clamp times were observed. During the follow-up period, the resection group has shown lower incidence of TIA/CVA and the overall mortality was also lower in this group of patients.
Conclusion: The resection group in our study has shown the trend toward lower incidence of TIA/CVA and statistically significant decrease of overall mortality. This finding can support routine LAA resection during surgical ablation of atrial fibrillation.
Keywords: Atrial fibrillation; Cerebrovascular event; LAA preservation; LAA resection
Received: January 25, 2015; Revised: March 5, 2015; Accepted: March 6, 2015; Published: June 1, 2015 Show citation
ACS | AIP | APA | ASA | Harvard | Chicago | Chicago Notes | IEEE | ISO690 | MLA | NLM | Turabian | Vancouver |
References
- M. Nakamura, H. Niinuma, M. Chiba, et al., Effect of the Maze procedure for atrial fibrillation on atrial and brain natriuretic peptide, American Journal of Cardiology 79 (1997) 966-970.
Go to original source...
Go to PubMed...
- M.B. Zimmerman, E.H. Blaine, E.M. Stricker, Water intake in hypovolemic sheep: effects of crushing the left atrial appendage, Science 211 (1981) 489-491.
Go to original source...
Go to PubMed...
- P. Massoudy, S. Beblo, P. Raschke, et al., Influence of intact left atrial appendage on hemodynamic parameters of isolated Guinea pig heart, European Journal of Medical Research 3 (1998) 470-474.
Go to PubMed...
- B.D. Hoit, M. Gabel, Influence of left ventricular dysfunction on the role of atrial contraction, Journal of the American College of Cardiology 36 (2000) 1713-1719.
Go to original source...
Go to PubMed...
- T. Tabata, T. Oki, N. Fukuda, et al., Influence of aging on left atrial appendage flow velocity patterns in normal subjects, Journal of the American Society of Echocardiography 9 (1996) 274-280.
Go to original source...
Go to PubMed...
- M. Bilge, B. Eryonucu, N. Guler, et al., Transesophageal echocardiography assessment of left atrial appendage function in untreated systemic hypertensive patients in sinus rhythm, Journal of the American Society of Echocardiography 13 (2000) 271-276.
Go to original source...
Go to PubMed...
- J.L. Blackshear, J.A. Odell, Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation, Annals of Thoracic Surgery 61 (1996) 755-759.
Go to original source...
Go to PubMed...
- A.J. Camm, G.I.H. Lip, R. De Caterina, et al., 2012 focused update of the ESC Guidelines for the management of atrial fibrillation, European Heart Journal 33 (2012) 2719-2747.
Go to original source...
Go to PubMed...
- J.S. Healey, E. Crystal, A. Lamy, et al., Left Atrial Appendage Occlusion Study (LAAOS): results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke, American Heart Journal 150 (2005) 288-293.
Go to original source...
Go to PubMed...
- O. Onalan, E. Crystal, Left atrial appendage exclusion for stroke prevention in patients with nonrheumatic atrial fibrillation, Stroke 38 (2 Suppl.) (2007) 624-630.
Go to original source...
Go to PubMed...
- A.D. Nagpal, L. Torracca, A. Fumero, et al., Concurrent prophylactic left atrial appendage exclusion: results from a randomized controlled trial pilot study, European Journal of Cardiothoracic Surgery 36 (2009) 553-557.
Go to original source...
Go to PubMed...
- J.L. Cox, N. Ad, T. Palazzo, Impact of the maze procedure on the stroke rate in patients with atrial fibrillation, Journal of Thoracic and Cardiovascular Surgery 118 (1999) 833-840.
Go to original source...
Go to PubMed...
- W.J. Johnson, A.K. Ganjoo, C.D. Stone, The left atrial appendage: our most lethal human attachment: surgical implication, European Journal of Cardiothoracic Surgery 17 (2000) 718-722.
Go to original source...
Go to PubMed...
- S.H. Ostermayer, M. Reisman, P.H. Kramer, et al., Percutaneous left atrial appendage transcatheter occlusion (PLAATO) to prevent stroke in high-risk patients with nonrheumatic atrial fibrillation: results from the international multi-center feasibility trials, Journal of the American College of Cardiology 46 (2005) 9-14.
Go to original source...
Go to PubMed...
- H.T. Sie, W.P. Beukema, A.R. Misier, et al., Radiofrequency modified maze in patients with atrial fibrillation undergoing concomitant cardiac surgery, Journal of Thoracic and Cardiovascular Surgery 2 (2001) 249-256.
Go to original source...
Go to PubMed...
- J. Shirani, J. Alaeddini, Structural remodelling of the left atrial appendage in patients with chronic non-valvular atrial fibrillation: implications for thrombus formation, systemic embolism and assessment by TEE, Cardiovascular Pathology 9 (2000) 95-101.
Go to original source...
Go to PubMed...
- L. Di Biase, J.D. Burkhardt, P. Mohanty, et al., Left atrial appendage: an underrecognized trigger site for atrial fibrillation, Circulation 122 (2010) 109-118.
Go to original source...
Go to PubMed...
- Y. Takahashi, P. Sanders, M. Rotter, M. Haissaguerre, Disconnection of the left atrial appendage for elimination of foci maintaining atrial fibrillation, Journal of Cardiovascular Electrophysiology 16 (2005) 917-919.
Go to original source...
Go to PubMed...
- J. Šťásek, J. Biz, Z. Vavera, et al., Percutaneous exclusion of the left atrial appendage in prevention of systemic embolism, Cor et Vasa 54 (2012) e156-e161.
Go to original source...
- P. Kala, M. Aschermann, Novel methods in interventional cardiology and cardiac surgery, Cor et Vasa 54 (2012) e135-e136.
Go to original source...
- A.S. Kanderian, A.M. Gillinov, G. Pettersson, et al., Success of surgical left atrial appendage closure, Journal of the American College of Cardiology 52 (2008) 924-929.
Go to original source...
Go to PubMed...
- M.A. Gillinov, G. Pettersson, D.M. Cosgrove III, Stapled excision of the left atrial appendage, Journal of Thoracic and Cardiovascular Surgery 129 (2005) 679-680.
Go to original source...
Go to PubMed...
- E.S. Katz, T. Tsiamtsiouris, R.M. Applebaum, Surgical left atrial appendage ligation is frequently incomplete: a transesophageal echocardiographic study, Journal of the American College of Cardiology 36 (2000) 468-471.
Go to original source...
Go to PubMed...