Cor Vasa 2015, 57(2):e63-e69 | DOI: 10.1016/j.crvasa.2015.02.013
Immediate coronary artery bypass graft surgery for acute coronary syndrome - Outcomes and trends over the past eight years
- a Kardiochirurgické centrum, Fakultní nemocnice Ostrava, Ostrava, Česká republika
- b Kardiologie, Městská nemocnice Ostrava, Ostrava, Česká republika
- c Kardiovaskulární oddělení, Fakultní nemocnice Ostrava, Ostrava, Česká republika
Background: Patients with acute coronary syndrome (ACS) who are indicated for an immediate cardiac procedure represent a high-risk population, burdened with an increased frequency of serious postoperative complications and higher mortality. In our study, we present the outcomes and trends within a group of patients who underwent a surgical procedure at our centre between 2006 and 2013.
Methods: We retrospectively analyzed data obtained from the National Registry of Cardiac Surgery for the period between 2006 and 2013; the patient population was further subdivided into two time periods, in order to facilitate the comparison: 2006-2009, n = 185; 2010-2013, n = 112. Furthermore, three groups were defined within each of the time periods, according to the main reason for performing the emergency surgery: unstable angina (UA), acute myocardial infarction (AMI) and cardiogenic shock (CS). Consequently, corresponding groups in both time periods were compared.
The main observed parameter was the postoperative mortality within 30 days from the procedure. Other analyzed attributes included the overall length of stay, length of ICU stay, ventilation time and the number of postoperative complications (reoperation due to bleeding, infectious complications of the sternotomy, renal failure requiring haemodialysis, multiple organ failure, stroke).
Results: Immediate surgical procedures represented on average 6.45% (4.7-9.2%) of the total number of surgeries performed at our centre per year between 2006 and 2013. The number of this type of surgery manifests a downward trend: 7.7% (2006-2009) vs. 5.2% (2010-2013). We also noted changes in the trends of the number of patients undergoing surgery due to UA: 40% (2006-2009) vs. 25% (2010-2013), AMI: 50% (2006-2009) vs. 55% (2010-2013) and CS: 11% (2006-2009) vs. 20% (2010-2013). The thirty-day mortality in the whole patient group was 15.49%: 12.4% (2006-2009) and 20.5% (2010-2013).
Conclusions: The analysis of our patient file shows a decreasing trend in the number of patients undergoing emergency surgery due to ACS in our centre in the course of the last eight years. Between 2010 and 2013, the proportional representation of patients undergoing surgery due to UA decreased, while the percentage of patients undergoing surgery due to AMI and CS increased. Within the population of patients with ACS, we were also able to determine an increased frequency of some risk factors and increased thirty-day mortality among patients undergoing surgery.
Keywords: Acute coronary syndrome; Coronary artery bypass grafting; Immediate surgery
Received: December 30, 2014; Revised: February 20, 2015; Accepted: February 20, 2015; Published: April 1, 2015 Show citation
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References
- J. Bělohlávek, Doporučený postup pro diagnostiku a léčbu akutních koronárních syndromů bez elevací ST úseků na EKG, Vnitřní lékařství 54 (Suppl. 1) (2008) 1S7-1S23 (Cor et Vasa 50 (Suppl) (2008) 1S7-1S23).
- M. Caceres, F. Esmailian, J.D. Moriguchi, et al., Mechanical circulatory support in cardiogenic shock following an acute myocardial infarction: a systematic review, Journal of Cardiac Surgery 29 (5) (2014) 743-751.
Go to original source...
Go to PubMed...
- R.V. Jeger, D. Radovanovic, P.R. Hunziker, et al., Ten-year trends in the incidence and treatment of cardiogenic shock, Annals of Internal Medicine 149 (9) (2008) 618-626.
Go to original source...
Go to PubMed...
- A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators, New England Journal of Medicine 335 (1996) 775-782.
- L. Dubey, S. Sharma, M. Gautam, et al., Cardiogenic shock complicating acute myocardial infarction - a review, Acta Cardiologica 66 (2011) 691-699.
Go to original source...
Go to PubMed...
- V. Menon, Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction: a report from the SHOCK Trial Registry. Should we emergently revascularize occluded coronaries in cardiogenic shock, Journal of the American College of Cardiology 36 (3 Suppl. A) (2000) 1110-1116.
Go to original source...
Go to PubMed...
- C.R. Thompson, C.E. Buller, L.A. Sleeper, et al., Cardiogenic shock due to acute severe mitral regurgitation complicating acute myocardial infarction: a report from the SHOCK Trial Registry. SHould we use emergently revascularize Occluded Coronaries in cardiogenic shocK?, Journal of the American College of Cardiology 36 (3 Suppl. A) (2000) 1104-1109.
Go to original source...
Go to PubMed...
- J. Slater, Cardiogenic shock due to cardiac free-wall rupture or tamponade after acute myocardial infarction: a report from the SHOCK Trial Registry. Should we emergently revascularize occluded coronaries for cardiogenic shock?, Journal of the American College of Cardiology 36 (3 Suppl A) (2000) 1117-1122.
Go to original source...
Go to PubMed...
- P. Sergeant, E. Blackstone, B. Meyns, Early and late outcome after CABG in patients with evolving myocardial infarction, European Journal of Cardio-Thoracic Surgery 11 (5) (1997) 848-856.
Go to original source...
Go to PubMed...
- M. Hata, M. Shiono, A. Sezai, et al., Outcome of emergency conventional coronary surgery for acute coronary syndrome due to left main coronary disease, Annals of Thoracic and Cardiovascular Surgery 12 (2006) 28-31.
Go to PubMed...
- K. Alexiou, U. Kappert, A. Staroske, et al., Coronary surgery for acute coronary syndrome: which determinants of outcome remain?, Clinical Research in Cardiology 97 (2008) 601-608.
Go to original source...
Go to PubMed...
- E. Ferrari, N. Stalder, L.K. von Segesser, On-pump beating heart coronary surgery for high risk patients requiring emergency multiple coronary artery bypass grafting, Journal of Cardiothoracic Surgery [Internet] 3 (1) (2008), Available from: http://ezproxy.muni.cz/login?url=http://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,cookie,uid&db=edselc&AN=edselc.2-52.0-48249088059〈=cs&site=eds-live≻ope=site.
Go to original source...
Go to PubMed...
- A.J. Rastan, J.I. Eckenstein, B. Hentschel, et al., Emergency coronary artery bypass graft surgery for acute coronary syndrome: beating heart versus conventional cardioplegic cardiac arrest strategies, Circulation 114 (Suppl. 1) (2006) I477-I485.
Go to original source...
Go to PubMed...
- C. Hagl, N. Khaladj, S. Peterss, et al., Acute treatment of ST-segment-elevation myocardial infarction: is there a role for the cardiac surgeon?, Annals of Thoracic Surgery 88 (2009) 1786-1792.
Go to original source...
Go to PubMed...
- S.R. Mehta, Routine vs. selective invasive strategies in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials, JAMA 293 (2005) 2908-2917.
Go to original source...
Go to PubMed...
- R.H. Jones, E.L. Hannan, K.E. Hammermeister, et al., Identification of preoperative variables needed for risk adjustment of short-term mortality after coronary artery bypass graft surgery. The Working Group Panel on the Cooperative CABG Database Project, Journal of the American College of Cardiology 28 (1996) 1478-1487.
Go to original source...
Go to PubMed...
- B. Tomasco, A. Cappiello, R. Fiorilli, et al., Surgical revascularization for acute coronary insufficiency: analysis of risk factors for hospital mortality, Annals of Thoracic Surgery 64 (1997) 678-683.
Go to original source...
Go to PubMed...
- A.K. Darwazah, I. Islim, B. Hanbali, et al., Emergency coronary artery bypass surgery after failed percutaneous coronary intervention, Journal of Cardiovascular Surgery (Torino) 50 (2009) 795-800.
Go to PubMed...
- D.C. Lee, M.C. Oz, A.D. Weinberg, et al., Appropriate timing of surgical intervention after transmural acute myocardial infarction, Journal of Thoracic and Cardiovascular Surgery 125 (2003) 115-120.
Go to original source...
Go to PubMed...
- J.S. Hochman, L.A. Sleeper, J.G. Webb, et al., Early revascularization in acute myocardial infarction complicated by cardiogenic shock, New England Journal of Medicine 341 (1999) 625-634.
Go to original source...
Go to PubMed...
- A. Assmann, U. Boeken, P. Akhyari, A. Lichtenberg, Appropriate timing of coronary artery bypass grafting after acute myocardial infarction, Thoracic and Cardiovascular Surgeon 60 (2012) 446-451.
Go to original source...
Go to PubMed...
- N. Khaladj, D. Bobylev, S. Peterss, et al., Immediate surgical coronary revascularisation in patients presenting with acute myocardial infarction, Journal of Cardiothoracic Surgery 8 (2013) 167.
Go to original source...
Go to PubMed...
- A. Lamy, P.J. Devereaux, D. Prabhakaran, et al., Off-pump or on-pump coronary-artery bypass grafting at 30 days, New England Journal of Medicine 366 (2012) 1489-1497.
Go to original source...
Go to PubMed...
- A. Yamaguchi, T. Murayama, [Emergency coronary artery bypass grafting for acute coronary syndrome], Masui Japanese Journal of Anesthesiology 61 (2012) 932-942 [Article in Japanese].
- H. Nishi, T. Sakaguchi, S. Miyagawa, et al., Optimal coronary artery bypass grafting strategy for acute coronary syndrome, General Thoracic and Cardiovascular Surgery 62 (2014) 357-363.
Go to original source...
Go to PubMed...
- L. Harling, M. Moscarelli, E. Kidher, et al., The effect of off-pump coronary artery bypass on mortality after acute coronary syndrome: a meta-analysis, International Journal of Cardiology 169 (2013) 339-348.
Go to original source...
Go to PubMed...
- H. Thiele, G. Schuler, F.-J. Neumann, et al., Intraaortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock: design and rationale of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial, American Heart Journal 163 (2012) 938-945.
Go to original source...
Go to PubMed...
- M. Maganti, S.J. Brister, T.M. Yau, et al., Changing trends in emergency coronary bypass surgery, Journal of Thoracic and Cardiovascular Surgery 142 (2011) 816-822.
Go to original source...
Go to PubMed...
- M.H. Khan, B.J. Corbett, S.M. Hollenberg, Mechanical circulatory support in acute cardiogenic shock, F1000Prime Reports [Internet] 6 (2014), Available from: http://www.scopus.com/inward/record.url?eid=2-s2.0-84908255982∂nerID=40&md5=20800b84a7a8c81cc91a86b7a39db0d5.