Cor Vasa 2013, 55(5):e449-e452 | DOI: 10.1016/j.crvasa.2013.01.001

Acute myocardial infarction type 2 secondary to the obstructive sleep apnea

Filip M. Szymanski*, Grzegorz Karpinski, Anna E. Platek, Krzysztof J. Filipiak
1st Department of Cardiology, Medical University of Warsaw, Varšava, Polsko

We report a case of a 54-year-old obese, loudly snoring male, who presented to the hospital with typical ischemic chest pain of early morning onset, and high blood pressure values. A standard 12-lead ECG performed on admission showed ST-segment elevation in leads II, III, aVF, V1 and ST segment depression in leads V2 to V4, but coronary angiography revealed no evidence of plaque rupture or erosion in an epicardial coronary vessel. Performed polysomnography confirmed severe obstructive sleep apnea (OSA). According to the universal definition of myocardial infarction the patient was diagnosed with acute ST-segment elevation myocardial infarction type 2, caused probably by sudden blood pressure rise secondary to apnea episode in the course of OSA. The patient was treated with continuous positive airway pressure device and suffered no further adverse cardiovascular event during 12 months of follow-up. The case highlights importance of further investigation of novel risk factors such as OSA, and possibly listing it as one of the causes of acute myocardial infarction type 2.

Keywords: Hypertension; Myocardial infarction; Obstructive sleep apnea; Risk factors

Received: December 11, 2012; Revised: December 29, 2012; Accepted: January 2, 2013; Published: October 1, 2013  Show citation

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Szymanski FM, Karpinski G, Platek AE, Filipiak KJ. Acute myocardial infarction type 2 secondary to the obstructive sleep apnea. Cor Vasa. 2013;55(5):e449-452. doi: 10.1016/j.crvasa.2013.01.001.
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References

  1. V.K. Somers, D.P. White, R. Amin, et al., Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing, Journal of the American College of Cardiology 52 (2008) 686-717. Go to original source... Go to PubMed...
  2. F.M. Szymanski, G. Karpinski, A. Hrynkiewicz-Szymanska, et al., Resistant hypertension in an obese patient with obvious obstructive sleep apnea and occult pheochromocytoma, Canadian Journal of Cardiology 397 (2012) 5-7. Go to original source... Go to PubMed...
  3. K. Thygesen, J.S. Alpert, A.S. Jaffe, et al., Third universal definition of myocardial infarction, European Heart Journal 33 (2012) 2551-2567. Go to original source... Go to PubMed...
  4. A. Hrynkiewicz-Szymanska, F.M. Szymanski, K.J. Filipiak, et al., Can obstructive sleep apnea be a cause of in-stent thrombosis?, Sleep and Breathing 15 (2011) 607-609. Go to original source... Go to PubMed...
  5. L. Saaby, T.S. Poulsen, S. Hosbond, et al., Relative occurrence and characteristics of type 1 versus type 2 myocardial infarction, European Heart Journal Supplements 33 (2012) 634. Go to original source...
  6. A.I. Larsen, P.D. Galbraith, W.A. Ghali, et al., Characteristics and outcomes of patients with acute myocardial infarction and angiographically normal coronary arteries, American Journal of Cardiology 95 (2005) 261-263. Go to original source... Go to PubMed...
  7. M.M Lui, D.C. Lam, M.S. Ip, Significance of endothelial dysfunction in sleep-related breathing disorder, Respirology 18 (2013) 39-46. Go to original source... Go to PubMed...
  8. F.H. Kuniyoshi, A. Garcia-Touchard, A.S. Gami, et al., Day-night variation of acute myocardial infarction in obstructive sleep apnea, Journal of the American College of Cardiology 52 (2008) 343-346. Go to original source... Go to PubMed...




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