Cor Vasa 2008, 50(2):55-59 | DOI: 10.33678/cor.2008.027

Reperfusion therapy in ST-segment elevation myocardial infarction - data from a pilot registry of myocardial infarction

Zdeněk Monhart^1,*, Václav Faltus^2,3, Hana Grünfeldová^3,4, Alena Kadlečková³, Dana Ryšavá⁵, Tomáš Velimský⁶, Lubomír Ballek⁷, Ján Hubač⁸, Petr Janský⁹, Jana Zvárová²

¹ Interní oddělení, Nemocnice Znojmo

² Centrum biomedicínckých informací, Praha

³ Ústav počítačových věd AV ČR, v. v. i., Praha

⁴ Interní oddělení, Nemocnice Čáslav

⁵ Interní oddělení, Nemocnice Kutná Hora

⁶ Interní oddělení, Nemocnice Písek

⁷ Interní oddělení, Nemocnice Jindřichův Hradec

⁸ Interní oddělení, Nemocnice Chrudim

⁹ Kardiovaskulární centrum, Fakultní nemocnice Motol, Praha, Česká republika

Aim:
To assess utilization of primary reperfusion therapy in patients with acute phase of ST-segment elevation myocardial infarction (STEMI) in the Czech Republic.

Methods:
A total of 744 consecutive patients with STEMI from years 2003-2006 were included in the study. Also, data on their demographics and reperfusion strategy were collected. An assessed clinical outcome was in-hospital mortality.

Results:
The mean age of STEMI patients was 66.9 ± 12.6 years. The vast majority were men (62.4%). A total of 68.6% STEMI patients received primary reperfusion treatment, 97.0% of them were referred for PPCI and 3.6% were treated with fibrinolytic therapy. Women and elderly patients were less likely to receive reperfusion therapy. The in-hospital mortality was 11.3% for all STEMI patients; 3.5% and 25.7% in the reperfused and non-reperfused groups, (p < 0.001). When adjusting for age, the effect of reperfusion therapy remained significant.

Conclusions:
In-hospital mortality was significantly reduced in a subgroup of patients who underwent primary reperfusion treatment (PPCI or fibrinolytic therapy). The PPCI represents the entirely prevalent form of reperfusion strategy in the Czech Republic.

Keywords: Myocardial infarction; Reperfusion therapy; Mortality

Published: February 1, 2008  Show citation