Cor Vasa 2004, 45(11):558-560
The potential for surgical treatment in patients with left ventricular ischemic dysfunction. The STICH study
- 1 Klinika kardiologie
- 2 Klinika kardiovaskulární chirurgie, Institut klinické a experimentální medicíny, Praha, Česká republika
The STICH study is a multicentric, international randomized study designed to test, in patients with coronary heart disease and coronary involvement eligible for surgical revascularization and with left ventricular dysfunction (ejection fraction £ 35%), two hypotheses: 1. Whether coronary artery bypass grafting (CABG) with intensive drug therapy improve the long-term prognosis versus the conservative tactics; 2. Whether revascularization, combined with an antiremodeling procedure on the left ventricle, improves the prognosis as compared with simple revascularization. Patients without a critical finding on the coronary arteries and free of critical symptomatology are randomized into Group A to receive medical treatment or CABG if the left ventricle is not suitable for reconstruction. Patients eligible for left ventricular reconstruction (Group B) will be on medical treatment or undergo CABG only or CABG combined with left ventricular reconstruction. Patients with a critical finding or symptomatology are randomized into Group C scheduled either for CABG only or CABG combined with left ventricular reconstruction. Regular follow-up is scheduled for a period of four years.
Keywords: Heart failure surgery; Left ventricular reconstruction; Revascularization in left ventricular dysfunction
Published: November 1, 2004 Show citation