Cor Vasa 2004, 45(7):339-342
A follow-up of myocardial and pulmonary 123I MIBG accumulation. A contribution to study of graft denervation and sympathetic hyperactivation following heart transplantation
- 1 Klinika kardiologie
- 2 Radioizotopové pracoviště
- 3 Klinika kardiovaskulární chirurgie, Institut klinické a experimentální medicíny, Praha, Česká republika
A total of 34 patients following orthotopic heart transplantation were examined using 123I metaiodobenzyl guanidine (MIBG) scintigraphy. We found low rates of myocardial MIBG accumulation suggesting persistent sympathetic graft denervation. Pulmonary MIBG accumulation was increased, presumably due to sympathetic hyperactivation and pulmonary endothelial dysfunction. No association was demonstrated between scintigraphic findings and coronary graft lesions.
Keywords: Heart transplantation; Graft denervation; Methaiodobenzyl guanidine accumulation
Published: July 1, 2004 Show citation
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Málek I, Buncová M, Kocík M, Janek B, Pirk J. A follow-up of myocardial and pulmonary 123I MIBG accumulation. A contribution to study of graft denervation and sympathetic hyperactivation following heart transplantation. Cor Vasa. 2004;45(7):339-342.