Cor Vasa 2018, 60(5):e448-e451 | DOI: 10.1016/j.crvasa.2017.06.010

Iatrogenic life-threatening condition in a patient with multiple rare disorders

Martyna Zaleska^a, Olga Możeńska^a, Mariola Laszuk^a, Piotr Suwalski^b,c, Dariusz Artur Kosior^d,*

^a Department of Cardiology and Hypertension, Central Research Hospital, The Ministry of the Interior, Wołoska 137, 02-507 Warsaw, Mazovia, Poland

^b Department of Cardiac Surgery, Central Research Hospital, The Ministry of the Interior, Wołoska 137, 02-507 Warsaw, Mazovia, Poland

^c Faculty of Health Sciences, Pulaski University, Malczewskiego 29, 26-600 Radom, Mazovia, Poland

^d Department of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Mazovia, Poland

Andersen-Tawil syndrome (long QT syndrome 7) is a rare inherited disorder, characterized by periodic paralysis, long QT, ventricular arrhythmias and skeletal abnormalities.
A 52-year-old female with a history of long QT syndrome, ICD implantation (secondary prevention of cardiac arrest) and systemic vasculitis was admitted due to an electrical storm caused by endocarditis. She was admitted again short after discharge due to multi-organ failure, which was caused probably by withdrawal of steroids and VKA. Characteristic dysmorphic features resulted in Andersen-Tawil syndrome suspicion.
If patients have one rare disorder they should not be excluded from further diagnostics, and very detailed outpatient care.

Keywords: Andersen-Tawil syndrome; Anticoagulant treatment; Congenital disease; Infectious endocarditis; Long QT syndrome; Multi-organ failure; Valve replacement

Received: January 28, 2017; Revised: June 19, 2017; Accepted: June 21, 2017; Published: October 1, 2018  Show citation