Cor Vasa 2015, 57(4):e320-e322 | DOI: 10.1016/j.crvasa.2014.12.006

Can amyotrophic lateral sclerosis chronically elevate troponin T?

Lukáš Mach^a,b, Tomáš Konečný^a,b,*, Allan S. Jaffe^a,c, Eric J. Sorenson^d, Guy S. Reeder^a

^a Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA

^b Mezinárodní centrum klinického výzkumu, Fakultní nemocnice u sv. Anny v Brně, Brno, Česká republika

^c Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA

^d Neuromuscular Division, Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA

A 57-year-old woman with progressive amyotrophic lateral sclerosis (ALS) presented repeatedly with atypical chest pain over a period of 4 years. Her initially normal cardiac troponin T (cTnT) value became progressively elevated during subsequent visits in the absence of clinically overt heart disease, and in the absence of alternative explanations for cTnT elevation. In this one patient there appeared to be a relationship between her rising levels of cTnT and increasing severity of ALS.

Keywords: Amyotrophic lateral sclerosis; Troponin; Troponin T

Received: November 29, 2014; Revised: December 15, 2014; Accepted: December 16, 2014; Published: August 1, 2015  Show citation