Cor Vasa 2005, 46(10):391-394
IQOLAN II (International Quality Of Life assessment of patients with Angina pectoris on Nitrate therapy) in the Czech Republic
- Kardiologie, Praha, Česká republika
The three-month IQOLAN II survey included patients with different degrees of severity of chronic coronary heart disease on long-term nitrate therapy in two divided daily doses. This technique of nitrate administration was replaced by therapy with Cardiket 120, a retard isosorbide dinitrate formula containing 120 mg of active the substance (SchwarzPharma) used once daily.
IQOLAN II documented the expected beneficial effect on clinical manifestations of coronary heart disease. The quality of life aspect will no doubt give us a more global perception of patients with chronic coronary heart disease. The wellbeing of the patient is dependent on many subjective criteria; the present survey includes a list of priority values associated with once-daily nitrate resulting in improved performance and overall functional activity.
In the absence of evidence from large clinical trials, this outcome lends support to the strategy of nitrate therapy.
Keywords: Nitrate; Coronary heart disease; Angina pectoris; Quality of life
Published: October 1, 2005 Show citation