Cor Vasa 2023, 65(3):514-524 | DOI: 10.33678/cor.2022.105

(Current role of mechanical thrombectomy in the treatment of acute ischemic stroke)

Jan Křeček^a, Boris Kožnar^a, Jakub Sulženko^a, Zdenko Stelmach^a, Petr Widimský^a, Ivana Štětkářová^b, Tomáš Peisker^b, Peter Vaško^b, Petr Mikulenka^b, David Lauer^b, Dušan Kučera

^a Kardiologická klinika, 3. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Královské Vinohrady, Praha

^b Neurologická klinika, 3. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Královské Vinohrady, Praha

Ischemic stroke is a severe condition with a high mortality and a serious risk of permanent functional dis- ability. The treatment of acute ischemic stroke has undergone a number of major changes in recent years - from systemic thrombolysis to the wide range of current mechanical thrombectomy modalities. Studies such as MR CLEAN, ESCAPE, EXTEND-IA, SWIFT PRIME and others have demonstrated improved outcomes in patients with large vessel occlusion when mechanical thrombectomy was used compared with best medical treatment including systemic thrombolysis. These results have completely changed the treatment paradigm. Currently, a wide variety of endovascular tools are available for mechanical thrombectomy and new ones are still under development. This paper aims to summarize the current options for the treatment of ischemic stroke by mechanical thrombectomy and to outline other therapy aspects of this disease.

Keywords: Acute ischemic stroke, Direct aspiration, Mechanical thrombectomy, Stent-retriever, Systemic thrombolysis

Received: September 16, 2022; Revised: September 16, 2022; Accepted: September 28, 2022; Published: June 20, 2023  Show citation