Cor Vasa 2021, 63(Suppl. 1):6-14

The year in cardiovascular medicine 2020: arrhythmias

Harry J.G.M. Crijns1*, Frits Prinzen2, Pier D. Lambiase3, Prashanthan Sanders4, Josep Brugada5
1 Department of Cardiology and Cardiovascular Research Centre Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, The Netherlands;
2 Department of Physiology and Cardiovascular Research Centre Maastricht (CARIM), University of Maastricht, Maastricht, The Netherlands;
3 University College London & Barts Heart Centre, London, UK
4 Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia
5 Cardiovascular Institute, Hospital Clinic, Pediatric Arrhythmia Unit, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain

Summary of the progress in arrhythmias in 2020. RACE4 and ALL-IN indicated that integrated nurse-led care improves outcomes in AF patients.3,4 The same was reported for early rhythm control therapy15 and cryoablation as initial AF treatment.25,26 Subcutaneous ICD was non-inferior to classical transvenous ICD therapy in PRAETORIAN.54 One mechanistic study showed that autoantibodies against misexpressed actin, keratin, and connexin-43 proteins create a blood-borne biomarker profile enhancing diagnosis of Brugada syndrome.50 Another mechanistic study indicated that transseptal LV pacing yields similar improvement in contractility as His bundle pacing whilst being more easy to execute.44 In PRE--DETERMINE a simple-to-use ECG risk score improved risk prediction in patients with ischemic heart disease possibly enhancing appropriate ICD therapy in high risk patients.58 (Graphical Abstract – see in original.)

Keywords: Guidelines, Randomized trial, Integrated care, Life style, Atrial fibrillation, Ventricular arrhythmias, Implantable defibrillator, His/left bundle pacing, Cardiogenetics

Received: June 7, 2021; Accepted: June 7, 2021; Published: July 1, 2021  Show citation

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Crijns HJGM, Prinzen F, Lambiase PD, Sanders P, Brugada J. The year in cardiovascular medicine 2020: arrhythmias. Cor Vasa. 2021;63(Suppl. 1):6-14.

Reproduced from: Crijns HJGM, Prinzen F, Lambiase PD, Sanders P, Brugada J. The year in cardiovascular medicine 2020: arrhythmias. Eur Heart J. 2021 Feb 1;42(5):499–507. https://doi.org/10.1093/eurheartj/ehaa1091, by permission of Oxford University Press on behalf of the European Society of Cardiology.

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