Cor Vasa 2018, 60(4):e345-e351 | DOI: 10.1016/j.crvasa.2018.02.007
Residual SYNTAX score can predict short- and long-term outcomes in patients with STEMI
- a Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turecko
- b Department of Cardiology, Sakarya University Faculty of Medicine, Sakarya, Turecko
- c Department of Internal Medicine, Sakarya University Faculty of Medicine, Sakarya, Turecko
Objectives: The prognostic value of residual SYNTAX score (rSS) has been observed in different patient groups. However, its prognostic value has not been compared in patients with ST segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI).
Methods: A total of 208 patients meeting the eligibility criteria were included in the study. Complete revascularisation (CR) was defined as rSS = 0 and incomplete revascularisation (IR) was defined as rSS ≥ 1.
Results: Among the sample, 78 patients (33.3%) were included in the CR group and 130 patients (67.7%) in the IR group. One patient (1.3%) in the CR group and 8 patients (6.2%) in the IR group died by day 30 (p < 0.01). The incidence of stent thrombosis, recurrent myocardial infarction (MI) and target lesion revascularisation (TLR) was similar between the two groups. During follow-up (mean 28.8 ± 7.1 months), 2 patients (2.6%) from the CR group and 10 (7.7%) patients from the IR group died (p > 0.05). The incidence of recurrent MI (18.5% vs. 7.7%; p < 0.01) and major adverse cardiovascular events (MACE) (24.6% vs. 7.7%; p < 0.01) were significantly higher in the IR group.
Conclusion: rSS, which is an indirect marker of incomplete revascularisation, was independently correlated with recurrent MI and MACE after STEMI.
Keywords: Incomplete revascularisation; Primary percutaneous coronary intervention; Residual SYNTAX score; ST-elevation myocardial infarction
Received: April 24, 2017; Revised: February 22, 2018; Accepted: February 26, 2018; Published: August 1, 2018 Show citation
ACS | AIP | APA | ASA | Harvard | Chicago | Chicago Notes | IEEE | ISO690 | MLA | NLM | Turabian | Vancouver |
References
- E.C. Keeley, J.A. Boura, C.L. Grines, Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials, Lancet 361 (2003) 13-20.
Go to original source...
Go to PubMed...
- E.L. Hannan, C. Wu, G. Walford, et al., Incomplete revascularization in the era of drug-eluting stents: impact on adverse outcomes, JACC: Cardiovascular Interventions 2 (2009) 17-25.
Go to original source...
Go to PubMed...
- Y.H. Kim, D.W. Park, J.Y. Lee, et al., Impact of angiographic complete revascularization after drug-eluting stent implantation or coronary artery bypass graft surgery for multivessel coronary artery disease, Circulation 123 (2011) 2373-2381.
Go to original source...
Go to PubMed...
- E.L. Hannan, M. Racz, D.R. Holmes, et al., Impact of completeness of percutaneous coronary intervention revascularization on long-term outcomes in the stent era, Circulation 113 (2006) 2406-2412.
Go to original source...
Go to PubMed...
- T. Palmerini, P. Genereux, A. Caixeta, et al., Prognostic value of the SYNTAX score in patients with acute coronary syndromes undergoing percutaneous coronary intervention: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) trial, Journal of the American College of Cardiology 57 (2011) 2389-2397.
Go to original source...
Go to PubMed...
- M.J. Van den Brand, B.J. Rensing, M.A. Morel, et al., The effect of completeness of revascularization on event-free survival at one year in the ARTS trial, Journal of the American College of Cardiology 39 (2002) 559-564.
Go to original source...
Go to PubMed...
- G. Sianos, M. Morel, A. Kappetein, et al., The SYNTAX score: an angiographic tool grading the complexity of coronary artery disease, EuroIntervention 1 (2005) 219-227.
Go to PubMed...
- C. Girasis, S. Garg, L. Raber, et al., SYNTAX score and clinical syntaxscore as predictors of very long-term clinical outcomes in patients undergoing percutaneous coronary interventions: a substudy of SIRolimus-eluting stent compared with pacliTAXel-eluting stent for coronary revascularization (SIRTAX) trial, European Heart Journal 32 (2011) 3115-3127.
Go to original source...
Go to PubMed...
- M. Magro, S. Nauta, C. Simsek, et al., Value of the SYNTAX score in patients treated by primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: the MI SYNTAXscore study, American Heart Journal 161 (2011) 771-781.
Go to original source...
Go to PubMed...
- E. Lev, R. Kornowski, H. Vaknin, et al., Comparison of the predictive value of four different risk scores for outcomes of patients with ST elevation acute myocardial infarction undergoing primary percutaneous coronary intervention, American Journal of Cardiology 102 (2008) 6-11.
Go to original source...
Go to PubMed...
- S. Garg, G. Sarno, P.W. Serruys, et al., Prediction of 1-year clinical outcomes using the SYNTAX score in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous intervention, JACC: Cardiovascular Interventions 4 (2011) 66-75.
Go to original source...
Go to PubMed...
- S. Kul, O. Akgul, H. Uyarel, et al., High SYNTAX score predicts worse in-hospital clinical outcomes in patients undergoing primary angioplasty for acute myocardial infarction, Coronary Artery Disease 23 (2012) 542-548.
Go to original source...
Go to PubMed...
- P. Genereux, T. Palmerini, A. Caixeta, et al., Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery) score, Journal of the American College of Cardiology 59 (2012) 2165-2174.
Go to original source...
Go to PubMed...
- B. Xu, Y.J. Yang, Y.L. Han, et al., Validation of residual SYNTAX score with second-generation drug-eluting stents: one year results from the prospective multicenter SEEDS study, EuroIntervention 10 (2014) 65-73.
Go to original source...
Go to PubMed...
- G.N. Levine, E.R. Bates, J.C. Blankenship, et al., 2015 ACC/ AHA/SCAI focused update on primary percutaneous coronary intervention for patients with ST-elevation myocardial infarction: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction, Journal of the American College of Cardiology 67 (2016) 1235-1250.
Go to original source...
Go to PubMed...
- V. Aggarwal, S. Rajpathak, M. Singh, et al., Clinical outcomes based on completeness of revascularisation in patients undergoing percutaneous coronary intervention: a meta-analysis of multivessel coronary artery disease studies, EuroIntervention 7 (2012) 1095-1102.
Go to original source...
Go to PubMed...
- D.S. Wald, J.K. Morris, N.J. Wald, et al., Randomized trial of preventive angioplasty in myocardial infarction, New England Journal of Medicine 369 (2013) 1115-1123.
Go to original source...
Go to PubMed...
- A.H. Gershlick, J.N. Khan, D.J. Kelly, et al., Randomized trial of complete versus lesion only revascularization in patients undergoing primary percutaneous coronary intervention for STEMI and multivessel disease: the CvLPRIT trial, Journal of the American College of Cardiology 65 (2015) 963-972.
Go to original source...
Go to PubMed...
- M. Kowalewski, V. Schulze, S. Berti, et al., Complete revascularisation in ST-elevation myocardial infarction and multivessel disease: meta-analysis of randomized controlled trials, Heart 101 (2015) 1309-1317.
Go to original source...
Go to PubMed...