Cor Vasa 2015, 57(2):e127-e132 | DOI: 10.1016/j.crvasa.2015.02.005
Incidence of small abdominal aortic aneurysms rupture, impact of comorbidities and our experience with rupture risk prediction based on wall stress assessment
- a II. chirurgická klinika, Fakultní nemocnice u sv. Anny v Brně, Brno, Česká republika
- b Lékařská fakulta Masarykovy univerzity, Brno, Česká republika
- c Ústav mechaniky těles, mechatroniky a biomechaniky, Vysoké učení technické, Brno, Česká republika
- d I. interní kardioangiologická klinika, Mezinárodní centrum klinického výzkumu (ICRC), Fakultní nemocnice u sv. Anny v Brně, Brno, Česká republika
Aim: Abdominal aortic aneurysm rupture (AAA) threatens a patient's life, requiring an urgent open repair or endovascular surgery. If an asymptomatic AAA is found before a rupture the next steps are directed by its diameter - if it is less than 55 mm the patient is dispensarized, and if it is more a repair is indicated. According to literary sources 10-24% of ruptured AAA are less than 55 mm in diameter, thus a significant portion of dispensarized patients are threatened by a rupture. The objective of our study was to determine a portion of small ruptured AAA repaired in our center in the last four years and try to identify potential risk factor. The secondary goal was to show our experience with a modern method of rupture prediction, using CT scans to compute the wall stress of AAA and thus predict its rupture risk.
Methods: A retrospective study of documentation of patients with ruptured AAA in last four years. CT findings were used to measure maximal diameter of ruptured AAA and portion of small AAA was determined. Some other important information from patient's medical history were also compared in both groups and statistically evaluated.
Results: 41 patients underwent an open repair of ruptured AAA. Out of this number 7 ruptured AAA were small, which is equivalent to 17.1%.
Conclusion: This finding shows us the shortages of the present indication criteria based on an AAA diameter. In accordance to these criteria patients with small AAA are dispensarized and thus a significant part of them are in risk of rupture.
Keywords: Abdominal aortic aneurysm; Prediction; Rupture; Small AAA; Wall stress assessment
Received: January 19, 2015; Accepted: February 16, 2015; Published: April 1, 2015 Show citation
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References
- M. Gawenda, J. Brunkwall, Ruptured abdominal aortic aneurysm: the state of play, Deutsches Ärzteblatt International 109 (2012) 727-732.
Go to original source...
Go to PubMed...
- F.L. Moll, J.T. Powell, G. Fraedrich, et al., Management of abdominal aortic aneurysms clinical practice guidelines of the European Society for Vascular Surgery, European Journal of Vascular and Endovascular Surgery 41 (2011) S1-S58.
Go to original source...
Go to PubMed...
- S.C. Nicholls, J.B. Gardner, M.H. Meissner, H.K. Johansen, Rupture in small abdominal aortic aneurysms, Journal of Vascular Surgery 28 (1998) 884-888.
Go to original source...
- A.J. Hall, E.F. Busse, D.J. McCarville, J.J. Burgess, Aortic wall tension as a predictive factor for abdominal aortic aneurysm rupture: improving the selection of patients for abdominal aortic aneurysm repair, Annals of Vascular Surgery 14 (2000) 152-157.
Go to original source...
Go to PubMed...
- G. Geroulakos, A. Nicolaides, Infrarenal abdominal aortic aneurysms less than five centimetres in diameter: the surgeon's dilemma, European Journal of Vascular Surgery 6 (1992) 616-622.
Go to original source...
- F.A. Lederle, G.R. Johnson, S.E. Wilson, et al., Rupture rate of large abdominal aortic aneurysms in patients refusing or unfit for elective repair, JAMA: Journal of the American Medical Association 287 (2002) 2968-2972.
Go to original source...
- R.C. Darling, C.R. Messina, D.C. Brewster, L.W. Ottinger, Autopsy study of unoperated abdominal aortic aneurysms. The case for early resection, Circulation 56 (3 Suppl.) (1977) II161-II164.
- A.K. Venkatasubramaniam, M.J. Fagan, T. Mehta, et al., A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms, European Journal of Vascular and Endovascular Surgery 28 (2004) 168-176.
Go to original source...
- T.C. Gasser, M. Auer, F. Labruto, et al., Biomechanical rupture risk assessment of abdominal aortic aneurysms: model complexity versus predictability of finite element simulations, European Journal of Vascular and Endovascular Surgery 40 (2010) 176-185.
Go to original source...
Go to PubMed...
- O. Schouten, V.H. van Waning, M.D. Kertai, et al., Perioperative and long-term cardiovascular outcomes in patients undergoing endovascular treatment compared with open vascular surgery for abdominal aortic aneurysm or iliaco-femoro-popliteal bypass, American Journal of Cardiology 96 (2005) 861-866.
Go to original source...
Go to PubMed...
- J.T. Powell, A.R. Brady, L.C. Brown, et al., Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms, Lancet 352 (1998) 1649-1655.
Go to original source...
- K.C. Kent, R.M. Zwolak, N.N. Egorova, et al., Analysis of risk factors for abdominal aortic aneurysm in a cohort of more than 3 million individuals, Journal of Vascular Surgery 52 (2010) 539-548.
Go to original source...
Go to PubMed...
- A.B. Wilmink, C.R. Quick, Epidemiology and potential for prevention of abdominal aortic aneurysm, British Journal of Surgery 85 (1998) 155-162.
Go to original source...
Go to PubMed...
- L.C. Brown, J.T. Powell, Risk factors for aneurysm rupture in patients kept under ultrasound surveillance, Annals of Surgery 230 (1999) 289-296.
Go to original source...
- Participants UKSAT, Long-term outcomes of immediate repair compared with surveillance of small abdominal aortic aneurysms, New England Journal of Medicine 346 (2002) 1445-1452.
Go to original source...
Go to PubMed...
- J.T. Powell, S.M. Gotensparre, M.J. Sweeting, et al., Rupture rates of small abdominal aortic aneurysms: a systematic review of the literature, European Journal of Vascular and Endovascular Surgery 41 (2011) 2-10.
Go to original source...
Go to PubMed...
- C. Forsell, J. Swedenborg, J. Roy, T.C. Gasser, The quasi-static failure properties of the abdominal aortic aneurysm wall estimated by a mixed experimental-numerical approach, Annals of Biomedical Engineering 41 (2013) 1554-1566.
Go to original source...
Go to PubMed...
- T.M. McGloughlin, B.J. Doyle, New approaches to abdominal aortic aneurysm rupture risk assessment: engineering insights with clinical gain, Arteriosclerosis, Thrombosis, and Vascular Biology 30 (2010) 1687-1694.
Go to original source...
Go to PubMed...
- S. Polzer, T.C. Gasser, J. Bursa, et al., Importance of material model in wall stress prediction in abdominal aortic aneurysms, Medical Engineering and Physics 35 (2013) 1282-1289.
Go to original source...
Go to PubMed...
- G. Martufi, M. Auer, J. Roy, et al., Multidimensional growth measurements of abdominal aortic aneurysms, Journal of Vascular Surgery 58 (2013) 748-755.
Go to original source...
Go to PubMed...