Cor Vasa 2014, 56(4):e311-e315 | DOI: 10.1016/j.crvasa.2014.06.002

Acute myocardial infarction, primary percutaneous coronary intervention and stent thrombosis in heart transplanted patient: Potential role of elevated coagulation factor VIII

Omar Gómez-Monterrosas^a, Diego Fernández^a, Salvatore Brugaletta^a, Giancarla Scalone^b, Ander Regueiro^a, Shuji Otsuki^a, Marta Farrero^a, Manel Sabaté^a,*

^a Cardiology Department, Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Spain

^b Catholic University of Sacred Heart, Rome, Italy

Elevated factor VIII levels have been established as thrombotic risk factor. In this case report, we describe a 51-year-old patient with a history of heart transplantation and acute myocardial infarction, treated by stent implantation who presented with sub-acute stent thrombosis. Elevated factor VIII levels were detected as most plausible cause of this thrombotic event. A review of the literature is also performed.

Keywords: Acute myocardial infarction; Elevated coagulation factor VIII; Heart transplantation; Primary percutaneous coronary intervention; Stent thrombosis

Received: April 13, 2014; Revised: June 4, 2014; Accepted: June 10, 2014; Published: August 1, 2014  Show citation