Cor Vasa 2013, 55(6):e487-e491 | DOI: 10.1016/j.crvasa.2013.07.005

The relationship between eosinophil and nondipper hypertension

Mustafa Kuzeytemiz, Mehmet Demir^*, Muhammed Şentürk

Kardiologická klinika, Bursa Yüksek İhtisas Education and Research Hospital, Bursa, Turecko

Aims: Nondipper hypertension is associated with increased cardiovascular morbidity and mortality. It is known that eosinophils play an important role in vasoconstriction and thrombosis. We aimed to compare the numbers of eosinophil counts of the patients with nondipper versus dipper hypertension.
Materials and method: This study included 70 hypertensive patients. Hypertensive patients were divided into two groups: 35 dipper patients (15 males, mean age 50.94 ± 11.13 years) and 35 nondipper patients (10 males, mean age 56.11 ± 11.05 years). Concurrent routine biochemical tests and eosinophil count on whole blood count were performed on these patients. These parameters were compared between groups.

Results: No statistically significant difference was found between two groups in terms of basic characteristics. Baseline characteristics of the study groups were comparable. Nondipper patients had a higher eosinophil and MPV value than dipper patients (148.86 ± 80 vs 304.57 ± 182 and 7.8 ± 0.12 vs 9.2 ± 0.2 fl, p < 0.001, respectively).

Conclusion: Eosinophil count and MPV value are higher in patients with nondipper hypertension when compared to the dippers.

Keywords: Eosinophil; Mean platelet volume; Nondipper hypertension; Thrombosis; Vasospasm

Received: July 1, 2013; Revised: July 13, 2013; Accepted: July 23, 2013; Published: December 1, 2013  Show citation