Cor Vasa 2013, 55(4):e377-e382 | DOI: 10.1016/j.crvasa.2013.06.004

Durable left ventricular assist devices - the minimum for referring cardiologists

Eva Goncalvesová
Oddelenie zlyhávania a transplantácie srdca, Národný ústav srdcových a cievnych chorôb, Bratislava, Slovensko

Growing population of advanced heart failure patients represents one of the major burdens for health care system. Heart transplantation is the gold standard for a severe HF but contraindications and lack of donors are ultimate hurdles for its widespread use. Heart replacement using durable mechanical circulatory support, e.g. continuous-flow left ventricular assist devices (LVAD), has grown fast in recent years. It is reasonable to assume that the number of LVAD implantations will continue to grow and will soon exceed the number of HTx. The review is intended to provide essential information on the results of clinical trials with continuous-flow left ventricular assist devices, indications and implantation timing. General and specific risks of LVAD surgery, short and long term courses are described, and risk assessment is outlined.

Keywords: Indication; Left ventricular assist device; Timing; Trial results

Received: April 22, 2013; Revised: June 19, 2013; Accepted: June 24, 2013; Published: August 1, 2013  Show citation

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Goncalvesová E. Durable left ventricular assist devices - the minimum for referring cardiologists. Cor Vasa. 2013;55(4):e377-382. doi: 10.1016/j.crvasa.2013.06.004.
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    References

    1. S.D. Russell, L.W. Miller, F.D. Pagani, Advanced heart failure: a call to action, Congestive Heart Failure 14 (2008) 316-321. Go to original source... Go to PubMed...
    2. J.V. McMurray, S. Adamopoulos, S.D. Anker, et al., ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012, European Heart Journal 33 (2012) 1787-1847. Go to original source... Go to PubMed...
    3. J.K Kirklin, D.C. Naftel, R.L. Kormos, et al., The Fourth INTERMACS Annual Report: 4,000 implants and counting, Journal of Heart and Lung Transplantation 31 (2012) 117-126. Go to original source... Go to PubMed...
    4. E.A. Rose, A.C. Gelijns, A.J. Moskowitz, et al., Long-term use of a left ventricular assist device for end-stage heart failure, The New England Journal of Medicine 345 (2001) 1435-1443. Go to original source... Go to PubMed...
    5. M.S. Slaughter, F.D. Pagani, J.G. Rogers, et al., HeartMate II Clinical Investigators, Clinical management of continuous-flow left ventricular assist devices in advanced heart failure, Journal of Heart and Lung Transplantation 29 (4 Suppl) (2010) S1-S39. Go to original source... Go to PubMed...
    6. L.W. Miller, F.D. Pagani, S.D. Russell, et al., Use of a continuous-flow device in patients awaiting heart transplantation, The New England Journal of Medicine 357 (2007) 885-896. Go to original source... Go to PubMed...
    7. F.D. Pagani, L.W. Miller, S.D. Russell, et al., HeartMate II Investigators, Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device, Journal of the American College of Cardiology 54 (2009) 312-321. Go to original source... Go to PubMed...
    8. M.S. Slaughter, J.G. Rogers, C.A. Milano, et al., HeartMate II Investigators, Advanced heart failure treated with continuous-flow left ventricular assist device, The New England Journal of Medicine 361 (2009) 2241-2251. Go to original source... Go to PubMed...
    9. R.C. Starling, Y. Naka, A.J. Boyle, et al., Results of the post-U.S. Food and Drug Administration-approval study with a continuous flow left ventricular assist device as a bridge to heart transplantation: a prospective study using the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support), Journal of the American College of Cardiology 57 (19) (2011) 1890-1898. Go to original source... Go to PubMed...
    10. R. John, Y. Naka, N.G. Smedira, et al., Continuous flow left ventricular assist device outcomes in commercial use compared with the prior clinical trial, Annals of Thoracic Surgery 92 (2011) 1406-1413. Go to original source... Go to PubMed...
    11. S.J. Park, C.A. Milano, A.J. Tatooles, et al., HeartMate II Clinical Investigators, Outcomes in advanced heart failure patients with left ventricular assist devices for destination therapy, Circulation: Heart Failure 5 (2012) 241-248. Go to original source... Go to PubMed...
    12. J. Lahpor, A. Khaghani, R. Hetzer, et al., European results with a continuous-flow ventricular assist device for advanced heart-failure patients, European Journal of Cardio-Thoracic Surgery 37 (2010) 357-361. Go to original source... Go to PubMed...
    13. M. Strüber, K. Sander, J. Lahpor, et al., HeartMate II left ventricular assist device; early European experience, European Journal of Cardio-Thoracic Surgery 34 (2008) 289-294. Go to original source... Go to PubMed...
    14. K.D. Aaronson, M.S. Slaughter, L.W. Miller, et al., HeartWare Ventricular Assist Device (HVAD) Bridge to Transplant ADVANCE Trial Investigators, Use of an intrapericardial, continuous-flow, centrifugal pump in patients awaiting heart transplantation, Circulation 125 (2012) 3191-3200. Go to original source... Go to PubMed...
    15. M. Strueber, G. O'Driscoll, P. Jansz, et al., HeartWare Investigators, Multicenter evaluation of an intrapericardial left ventricular assist system, Journal of the American College of Cardiology 57 (2011) 1375-1382. Go to original source... Go to PubMed...
    16. G.M. Wieselthaler, G. O'Driscoll, P. Jansz, et al., HVAD Clinical Investigators, Initial clinical experience with a novel left ventricular assist device with a magnetically levitated rotor in a multi-institutional trial, Journal of Heart and Lung Transplantation 29 (11) (2010) 1218-1225. Go to original source... Go to PubMed...
    17. M. Morshuis, A. El-Banayosy, L. Arusoglu, et al., European experience of DuraHeart magnetically levitated centrifugal left ventricular assist system, European Journal of Cardio-Thoracic Surgery 35 (2009) 1020-1027. Go to original source... Go to PubMed...
    18. J.G. Rogers, K.D. Aaronson, A.J. Boyle, et al., Continuous flow left ventricular assist device improves functional capacity and quality of life of advanced heart failure patients, Journal of the American College of Cardiology 55 (2010) 1826-1834. Go to original source... Go to PubMed...
    19. K. Lietz, J.W. Long, A.G. Kfoury, et al., Outcomes of left ventricular assist device implantation as destination therapy in the post-REMATCH era: implications for patient selection, Circulation 116 (2007) 497-505. Go to original source... Go to PubMed...
    20. J.C. Matthews, F.D. Pagani, J.W. Haft, et al., Model for end stage liver disease score predicts left ventricular assist device operative transfusion requirements, morbidity, and mortality, Circulation 12 (2010) 214-220. Go to original source... Go to PubMed...
    21. J.A. Yang, T.S. Kato, B.P. Shulman, et al., Liver dysfunction as a predictor of outcomes in patients with advanced heart failure requiring ventricular assist device support: Use of the Model of End-stage Liver Disease (MELD) and MELD eXcluding INR (MELD-XI) scoring system, Journal of Heart and Lung Transplantation 31 (6) (2012) 601-610. Go to original source... Go to PubMed...
    22. J.C. Matthews, T.M. Koelling, F.D. Pagani, et al., The right ventricular failure risk score a pre-operative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates, Journal of the American College of Cardiology 51 (2008) 2163-2172. Go to original source... Go to PubMed...
    23. J.R. Fitzpatrick 3rd, J.R. Frederick, V.M. Hsu, et al., Risk score derived from pre-operative data analysis predicts the need for biventricular mechanical circulatory support, Journal of Heart and Lung Transplantation 27 (2008) 1286-1292. Go to original source... Go to PubMed...
    24. R.L. Kormos, J.J. Teuteberg, F.D. Pagani, et al., HeartMate II Clinical Investigators, Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes, Journal of Thoracic and Cardiovascular Surgery 139 (2010) 1316-1324. Go to original source... Go to PubMed...
    25. W.L. Holman, R.L. Kormos, D.C. Naftel, et al., Predictors of death and transplant in patients with a mechanical circulatory support device: a multiinstitutional study, Journal of Heart and Lung Transplantation 28 (2009) 44-50. Go to original source... Go to PubMed...
    26. Y. Topilsky, J.K. Oh, D.K. Shah, et al., Echocardiographic predictors of adverse outcomes after continuous left ventricular assist device implantation, JACC Cardiovascular Imaging 4 (2011) 211-222. Go to original source... Go to PubMed...
    27. S.G. Drakos, L. Janicki, B.D. Horne, et al., Risk factors predictive of right ventricular failure after left ventricular assist device implantation, American Journal of Cardiology 105 (2010) 1030-1035. Go to original source... Go to PubMed...
    28. S. Puwanant, K.K. Hamilton, C.T. Klodell, et al., Tricuspid annular motion as a predictor of severe right ventricular failure after left ventricular assist device implantation, Journal of Heart and Lung Transplantation 27 (2008) 1102-1107. Go to original source... Go to PubMed...
    29. E.V. Potapov, A. Stepanenko, M. Dandel, et al., Tricuspid incompetence and geometry of the right ventricle as predictors of right ventricular function after implantation of a left ventricular assist device, Journal of Heart and Lung Transplantation 27 (2008) 1275-1281. Go to original source... Go to PubMed...
    30. T.S. Kato, M. Farr, P.C. Schulze, et al., Usefulness of two-dimensional echocardiographic parameters of the left side of the heart to predict right ventricular failure after left ventricular assist device implantation, American Journal of Cardiology 109 (2012) 246-251. Go to original source... Go to PubMed...
    31. M. Kukucka, A. Stepanenko, E. Potapov, et al., Right-to-left ventricular end-diastolic diameter ratio and prediction of right ventricular failure with continuous-flow left ventricular assist devices, Journal of Heart and Lung Transplantation 30 (2011) 64-69. Go to original source... Go to PubMed...
    32. M. Pettinari, S. Jacobs, F. Rega, et al., Are right ventricular risk scores useful? European Journal of Cardio-Thoracic Surgery 42 (2012) 621-626. Go to original source... Go to PubMed...
    33. E. Goncalvesová, M. Hulman, I. Olejárová, et al., Initial experience with an implantable left ventricular assist device in the heart transplant programme of the National Institute of Cardiovascular Diseases, Kardiológia Cardiology 17 (2008) 101-108.

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