Cor Vasa 2011, 53(12):717-721 | DOI: 10.33678/cor.2011.176

Development of tako-tsubo cardiomyopathy in a patient with hormonally active adrenal tumor - feochromocytome

Ivana Havlová1,*, Antonín Novák1, Jiří Herman1, Marian Bystroň1, Pavel Červinka1, Tomáš Zelinka2
1 K.Z., a.s. - Masarykova nemocnice v Ústí nad Labem, o.z., Klinika kardiologie, Ústí nad Labem
2 III. interní klinika - klinika endokrinologie a metabolismu, 1. lékařská fakulta Univerzity Karlovy a Všeobecné fakultní nemocnice, Praha, Česká republika

Tako-tsubo cardiomyopathy is characterized by transient left ventricular dysfunction connected with chest pain, ECG changes imitating acute myocardial infarction with cardiac markers elevation, without obstructive coronary artery disease, in consequence of stress situation. Exact cause of tako-tsubo cardiomyopathy remains unknown, although several patophysiological mechanisms have been proposed. Probable reason is a high level of catecholamines which causes a myocardial dysfunction. In our case report we describe a case of a 47-year-old female with tako-tsubo cardiomyopathy which was induced by catecholamine overproduction in association with pheochromocytoma of right adrenal gland.

Keywords: Tako-tsubo cardiomyopathy; Left ventricular dysfunction; Pheochromocytoma; Catecholamines; Toxic catecholamine cardiomyopathy

Published: December 1, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Havlová I, Novák A, Herman J, Bystroň M, Červinka P, Zelinka T. Development of tako-tsubo cardiomyopathy in a patient with hormonally active adrenal tumor - feochromocytome. Cor Vasa. 2011;53(12):717-721. doi: 10.33678/cor.2011.176.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Aschermann M, Aschermann O. Tako tsubo kardiomyopatie. Vnitřní Lék 2009;55:792-796.
    2. Obunai K, Schweitzer P. A case of takotsubo cardiomyopathy. Cardiol 2006;15:31-33.
    3. Vopelková J, Veselka J. Tako-tsubo syndrom - nový přírůstek do rodiny akutních stavů v kardiologii: aktuální sdělení. Vnitř Lék 2006;52:1066-1068. Go to PubMed...
    4. Bis J, Polanský P, Vojáček J, et al. Tako-tsubo kardiomyopatie. Interv Akut Kardiol 2006;5:227-230.
    5. Wittstein IA, Thieman DR, Lima JAC, et al. Neurohumoral features of myocardial stunning due to sudden emotional stress. NEJM 2005;352:539-548. Go to original source... Go to PubMed...
    6. Ueyama T. Emotional stress-induced tako-tsubo cardiomyopathy: animal model and molecular mechanism, Ann NY Acad Sci 2004;1018:437-444. Go to original source... Go to PubMed...
    7. Štrauch B, Zelinka T. Feochromocytom - klinické aspekty. Med Praxi 2009; 6:249-253.
    8. Zelinka T. Feochromocytom. Interní Med 2007;1:30-38.
    9. Laínez B, Ureña M, Álvarez V, et al. Iatrogenic tako-tsubo cardiomyopathy secondary to catecholamine administration. Rev Esp Cardiol 2009;62:1498-1499. Go to original source...
    10. Chia P, Foo D. Tako-tsubo cardiomyopathy precipitated by pheochromocytoma crisis. Cardiol J 2010;17:1-4. Go to original source... Go to PubMed...
    11. Rossi AP, Bing-You RG, Thomas LR. Recurrent takotsubo cardiomyopathy associated with pheochromocytoma. Endocr Pract 2009;15:560-562. Go to original source... Go to PubMed...
    12. Takizawa M, et al. A case of transient left ventricular ballooning with pheochromocytoma, supporting pathogenetic role of catecholamines in stress-induced cardiomyopathy or takotsubo cardiomyopathy. Int JCardiol 2007;114: E15-E17. Go to original source... Go to PubMed...
    13. Sutherland JA, Al Chekakie MO, Moran JF. Catecholamine-induced cardiomyopathy rapidly reversed with β-blocker therapy. Congest Heart Fail 2009;15:193-195. Go to original source... Go to PubMed...
    14. Silberbauer J, Hong P, Lloyd GW. Takotsubo cardiomyopathy (left ventricular ballooning syndrome) induced during dobutamine stress echocardiography. Eur J Echocardiogr 2008;9:136-138. Go to original source...
    15. Eric B, Tomich EB, Merchant E, et al. Takotsubo cardiomyopathy. http://emedicine.medscape.com/article/1513631-overview, Feb 2, 2011.
    16. Bybee KA, et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med 2004;141:858-865. Go to original source...
    17. Nanda S, Bhatt SP, Dale TH. Takotsubo cardiomyopathy: an insight into pathogenesis. Chest 2008;133:583-584. Go to original source... Go to PubMed...
    18. Jiang JP, Downing SE. Catecholamine cardiomyopathy: review and analysis of pathogenetic mechanisms. Yale J Biol Med 1990;63:581-591.
    19. Kassim TA, Clarke DD, Mai Q, et al. Catecholamine-induced cardiomyopathy. Endocr Practice 2008;14:1137-1149. Go to original source... Go to PubMed...

    Return to the content


    Cor et Vasa

    You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

    I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.


    No
    Yes