Cor Vasa 2010, 52(Suppl.):52-58 | DOI: 10.33678/cor.2010.206

Aspirin resistance after coronary artery bypass grafting

František Bednář1,*, Pavel Osmančík1, Tomáš Vaněk2, Petr Widimský1
1 III. interní-kardiologická klinika
2 Kardiochirurgická klinika, Kardiocentrum, Fakultní nemocnice Královské Vinohrady a 3. lékařská fakulta Univerzity Karlovy, Praha, Česká republika

Aspirin administration after surgical myocardial revascularization improves not only early patency, particularly that of the venous grafts but, also, and more importantly, it significantly improves clinical postoperative outcomes.
Several recent papers have consistently reported an inadequate inhibitory effect of aspirin on platelet function in the early postoperative period, giving rise to what is now referred to as acquired aspirin insufficiency (resistance). The paper is an extensive overview of current concepts regarding the issue including its pathogenesis, diagnosis, and clinical relevance. The paper includes a list of the authors' own publications addressing the topic.

Keywords: Aspirin resistance; Coronary artery bypass surgery; Platelets

Published: December 1, 2010  Show citation

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Bednář F, Osmančík P, Vaněk T, Widimský P. Aspirin resistance after coronary artery bypass grafting. Cor Vasa. 2010;52(Suppl.):52-58. doi: 10.33678/cor.2010.206.
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