Cor Vasa 2010, 52(10):639-642 | DOI: 10.33678/cor.2010.163

Fractional flow reserve in the diagnosis of focal and diffuse stenosis of coronary artery

Krystyna Prymusová1,*, Petr Kala2, Martin Poloczek2, Petr Jeřábek2, Otokar Boček2, Miroslav Vytiska2, Petr Neugebauer2
1 Oddělení kardiologie, Kardiocentrum, Nemocnice Podlesí, a. s., Třinec
2 Interní kardiologická klinika, Fakultní nemocnice Brno, Brno, Česká republika

We present the case report of a patient with a history of acute ST elevation myocardial infarction (STEMI) of the left ventricular inferolateral wall, treated with percutaneous coronary intervention (PCI) of the obtuse marginal branch. Residual diffuse stenosis of the left anterior descending artery (LAD) was tested functionally with fractional flow reserve (FFR). The lesion was evaluated as significant and was partially treated with PCI using implantation of two drug-eluting stents. The functionally optimal outcome enabled partial revascularization with residual borderline distal stenosis of LAD. Functional testing of borderline coronary stenoses using FFR in a cathether laboratory renders decision making about effective treatment significantly easier.

Keywords: Coronary heart disease; Percutaneous coronary intervention; Myocardial fractional flow reserve

Published: October 1, 2010  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Prymusová K, Kala P, Poloczek M, Jeřábek P, Boček O, Vytiska M, Neugebauer P. Fractional flow reserve in the diagnosis of focal and diffuse stenosis of coronary artery. Cor Vasa. 2010;52(10):639-642. doi: 10.33678/cor.2010.163.
Download citation

References

  1. Boden WE, O'Rourke RA, Teo KK,et al; COURAGE Trial Research Group. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med 2007;356:1503-1516. Go to original source... Go to PubMed...
  2. Fisher LD, Judkins MP, Lesperance J. Reproducibility of coronary arteriographic reading in the coronary artery surgery study (CASS). Cathet Cardiovasc Diagn 1982;8:565-575. Go to original source... Go to PubMed...
  3. Hamilos M, Muller O, De Bruyne B. The left main coronary artery deserves more than a quick look. Interv Cardiol 2010;2:7-11. Go to original source...
  4. Mintz GS, Painter JA, Pichard AD, et al. Atherosclerosis in angiographically "normal" coronary artery reference segments: an intravascular ultrasound study with clinical correlations. J Am Coll Cardiol 1995;25:1479-1485. Go to original source... Go to PubMed...
  5. Hau KW. Routine pressure-derived fractional flow reserve guidance: Application of FFR. Invasive Cardiol 2006;18:240-245.
  6. De Bruyne B, Pijls NHJ, Barbato E, et al. Intracoronary and intravenous adenosine 5'-triphosphate, adenosine, papaverine, and contrast medium to assess fractional flow reserve in humans. Circulation 2003;107:1877-1883. Go to original source...
  7. Pijls NH, van Schaardenburgh P, Manoharan G, et al. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study. J Am Coll Cardiol 2007;49:2105-2111. Go to original source... Go to PubMed...
  8. Tonino PA, De Bruyne B, Pijls NH, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 2009;360:213-224. Go to original source... Go to PubMed...
  9. Kočka V. Funkční měření v katetrizační laboratoři - aneb je koronarografie vždy dokonalá? Cor Vasa 2009;51(Suppl. 1):26-30. Go to original source...
  10. Kala P. Frakční průtoková rezerva, šedá zóna a lékové stenty. Interv Akut Kardiol 2005;4:59.
  11. Mokhtar OA, Armero S, Bonello L. A pitfall of fractional flow reserve measurement. J Invasive Cardiol 2010;22:E110-E111. Go to PubMed...




Cor et Vasa

You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.