Cor Vasa 2008, 50(3):104-108 | DOI: 10.33678/cor.2008.040

The cardiovascular risk profile in patients with co-existing coronary artery disease and aortic stenosis or sclerosis.

Kateřina Linhartová^1,2, Gabriela Štěrbáková², Roman Čerbák³

¹ Kardiovaskulární centrum dospělých Fakultní nemocnice v Motole, 1. lékařská fakulta Univerzity Karlovy, Praha

² I. interní klinika, Fakultní nemocnice Plzeň a Lékařská fakulta Univerzity Karlovy, Plzeň

³ Centrum kardiovaskulární a transplantační chirurgie, Brno, Česká republika

Aim:
To compare the cardiovascular risk in patients with significant coronary artery disease associated with aortic stenosis or sclerosis.

Method:
To compare the clinical, laboratory and angiographic data of consecutive patients with angiographically significant coronary artery disease associated with aortic stenosis (AS) (mean gradient ≥ 30 mmHg) or non-obstructive aortic sclerosis (mean gradient ≤ 10 mmHg).

Results:
A total of 127 patients with AS (85 males) and 101 patients with aortic sclerosis (76 males) were included into the study. Patients with AS were older (71 ± 7 vs. 66 ± 7 years; p < 0.001). The two groups did not differ significantly in the incidence of major cardiovascular risk factors: hyperlipidemia 78%, hypertension 83%, diabetes mellitus 37%, smoking 62%, LDL- a HDL-cholesterol levels, body mass index (28.9) or in the highly sensitive C-reactive protein levels. AS patients were shown to have more often multivessel coronary disease or left main trunk disease.

Conclusion:
Patients with coronary artery disease and AS are older compared with patients with associated aortic stenosis; both groups show a similar and most adverse cardiovascular risk profile.

Keywords: Aortic stenosis; Calcification; Coronary artery disease

Published: March 1, 2008  Show citation