Cor Vasa 2007, 49(5):192-194

Drug therapy of arterial hypertension in patients with significant aortic stenosis.

Kateřina Linhartová¹, Roman Čerbák², Jan Filipovský³, Gabriela Štěrbáková⁴

¹ Kardiovaskulární centrum, Fakultní nemocnice Motol, Praha

² Centrum kardiovaskulární a transplantační chirurgie, Brno

³ II. interní klinika

⁴ I. interní klinika, Lékařská fakulta Univerzity Karlovy v Plzni, Plzeň, Česká republika

Arterial hypertension affects 30-70% patients with aortic stenosis. There are no specific recommendations for drug treatment of this population of patients; to date, no consensus has been reached over vasodilator administration. The aim of our study was to determine the incidence of hypertension and the proportion of medically treated patients with aortic stenosis at the time of indication for surgery.
Data from a comprehensive examination of 225 patients (mean age 68 ± 9 years; 41% of women) with significant non-rheumatic calcified aortic stenosis (mean gradient 54 ± 17 mmHg) were analyzed. Arterial hypertension was present in 68% of patients; of these, 87% were on drug therapy. Vasodilator therapy was given to 54% hypertensives with aortic stenosis.
In our group, arterial hypertension was diagnosed in more than two thirds of patients with significant aortic stenosis; most of them were receiving drug therapy, vasodilators were common in the treatment of hypertension.

Keywords: Hypertension; Aortic stenosis; ACE inhibitors; Aortic valve calcification

Published: May 1, 2007  Show citation