Cor Vasa 2003, 44(11):565-566

Myocardial injury and full reversibility - will we identify the responsible gene and will it serve us?

Jan Šochman
Klinika kardiologie, Institut klinické a experimentální medicíny, Praha, Česká republika

As a dogma in cardiology, it is still believed that severely damaged myocardial structures in adult humans will not get repaired naturally. There have been attempts at modified regeneration using transformed and implanted stem or embryonic cells. However, a piece of evidence from the animal kingdom suggests the potential for full regeneration: a new mutation of the mitotic Mps 1 kinase responsible for complete replacement of absent myocardial structures. This is an exciting finding that provides support to concepts based on the replacement of lost tissue, lost structures, and lost function.

Keywords: Repair; Myocardial regeneration; Mitotic Mps 1 kinase; Myocardial infarction

Published: November 1, 2003  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Šochman J. Myocardial injury and full reversibility - will we identify the responsible gene and will it serve us? Cor Vasa. 2003;44(11):565-566.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)

    • Return to the content


    Cor et Vasa

    You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

    I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.


    No
    Yes